Magnesium Citrate, Trimagnesium Dicitrate, Magnesium Dicitrate, Trimagnesium Citrate Anhydrous, 3344-18-1

Magnesium Citrate, Trimagnesium Dicitrate, Magnesium Dicitrate, Trimagnesium Citrate Anhydrous, 3344-18-1

Magnesium Citrate (Trimagnesium Citrate)

Molecular Formula: C₁₂H₁₀Mg₃O₁₄ Molecular Weight: 451.12 g/mol CAS Number: 3344-18-1 Synonyms: Magnesium Dicitrate, Trimagnesium Citrate, Citric Acid Magnesium Salt, Trimagnesium Dicitrate

Physical and Chemical Properties

• Appearance: White powder

• Melting Point: 185 °C

• Density: Not clearly defined

• Solubility:

  • Poorly soluble in water

  • Readily soluble in dilute acids such as hydrochloric acid, nitric acid, and sulfuric acid

Biological and Pharmaceutical Profile

• Magnesium is one of the most abundant minerals in the human body.

• Magnesium citrate acts as an osmotic laxative agent with mild cathartic properties.

• It is widely used in pharmaceutical formulations as an inactive excipient or as a magnesium source.

• It stimulates nitric oxide synthesis, which enhances intestinal secretion.

• It also promotes the biosynthesis of platelet-activating factor, contributing to increased gastrointestinal activity.

• Due to these effects, it is commonly employed in laxative preparations.

Applications

• Pharmaceutical Industry: Active ingredient in laxatives, excipient in tablet formulations.

• Nutritional Supplements: Preferred magnesium source due to better absorption compared to other magnesium salts.

• Industrial Use: Magnesium plays a role in lightweight magnesium-aluminum alloy production.