Lithium Acetate, Lithium Monoacetate, Lithium Ethanoate, Lithium Acetate Anhydrous, Lithium Acetate Dihydrate, 546-89-4, 6108-17-4

LITHIUM ACETATE (LiCH₃COO)

PRODUCT IDENTIFICATION INFORMATION

CHEMICAL STRUCTURE

    Lithium Acetate (LiCH₃COO)
    
         H   O
          \  ||
           C—C—O⁻ Li⁺
          / 
         H
    
    Lithium Acetate
    (Acetic Acid Lithium Salt)

Molecular Formula (Anhydrous): LiC₂H₃O₂ (LiCH₃COO)
Molecular Formula (Dihydrate): LiC₂H₃O₂·2H₂O
SMILES: [Li+].CC(=O)[O-]
InChI: InChI=1S/C2H4O2.Li/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1
Functional Groups: Acetate group (CH₃COO⁻), Lithium ion (Li⁺)

SECTION 1: CHEMICAL IDENTITY AND DEFINITION

SECTION 2: PHYSICAL AND CHEMICAL PROPERTIES

SECTION 3: CHEMICAL PROPERTIES AND REACTIVITY

SECTION 4: COMPARISON OF LITHIUM COMPOUNDS

SECTION 5: PRODUCTION METHODS

Method 1: Reaction of Lithium Carbonate with Acetic Acid (Most Common Method)

• Reaction: Li₂CO₃ + 2CH₃COOH → 2LiCH₃COO + H₂O + CO₂

• Description: Lithium carbonate is reacted with acetic acid; Lithium acetate, water, and carbon dioxide are formed; Evaporation and crystallization yield the product; Most common industrial production method

Method 2: Neutralization of Lithium Hydroxide with Acetic Acid

• Reaction: LiOH + CH₃COOH → LiCH₃COO + H₂O

• Description: Lithium hydroxide is neutralized with acetic acid; Lithium acetate and water are formed; Evaporation and crystallization yield the product

Method 3: Metathesis Reaction of Lithium Chloride with Sodium Acetate

• Reaction: LiCl + CH₃COONa → LiCH₃COO + NaCl

• Description: Lithium chloride is reacted with sodium acetate; Lithium acetate and sodium chloride are formed; Purification yields the product

Method 4: Direct Reaction of Lithium Metal with Acetic Acid

• Reaction: 2Li + 2CH₃COOH → 2LiCH₃COO + H₂

• Description: Lithium metal is reacted with acetic acid; Lithium acetate and hydrogen gas are formed; High-purity product is obtained (laboratory scale)

SECTION 6: FUNCTIONAL PROPERTIES AND MECHANISM OF ACTION

SECTION 7: MAIN APPLICATION AREAS

SECTION 8: QUALITY SPECIFICATIONS

Lithium Acetate Anhydrous (546-89-4) Specifications

Lithium Acetate Dihydrate (6108-17-4) Specifications

SECTION 9: TOXICOLOGICAL PROFILE

SECTION 10: GHS CLASSIFICATION AND LABELING

GHS Classification (Compliant with CLP and UN GHS):

Note: Lithium acetate generally has a low hazard classification.

Signal Word: WARNING

Hazard Pictograms: GHS07 (Exclamation Mark)

Hazard Statements (H-Codes):

SECTION 11: PRECAUTIONARY STATEMENTS (P-CODES)

SECTION 12: FIRST AID MEASURES

SECTION 13: FIREFIGHTING MEASURES

SECTION 14: STORAGE AND SHELF LIFE

SECTION 15: PACKAGING OPTIONS

SECTION 16: TRANSPORT INFORMATION

SECTION 17: REGULATORY STATUS

SECTION 18: OTHER NAMES AND SYNONYMS

SECTION 19: SUMMARY TABLE

SECTION 20: CRITICAL WARNINGS AND BEST PRACTICES

CRITICAL WARNINGS:

• Causes serious eye irritation (H319). Use eye protection.

• Causes mild skin irritation (H316). Avoid skin contact.

• May cause respiratory irritation (H335). Avoid inhalation of dust.

• Slightly hygroscopic. Protect from moisture.

• Non-combustible but decomposes at high temperatures.

• Dihydrate form dehydrates at 70°C. Controlled drying required to obtain anhydrous form.

BEST PRACTICE RECOMMENDATIONS:

• Biochemistry / Molecular Biology: Use as buffer in DNA and RNA gel electrophoresis; Preferred in agarose gel electrophoresis; Provides pH stabilization; Requires high purity.

• Genetic Engineering: Use for yeast cell transformation; Makes cell wall permeable for DNA transformation; Softens cell wall.

• Polymer Industry: Use in PVC stabilization; Thermal stabilizer; Additive in polymer processing.

• Battery Industry: Use as electrolyte additive in lithium-ion batteries; Thin film electrode production; Improves battery performance.

• Handling: Use in well-ventilated areas; Avoid dust generation; Wear protective gloves, safety goggles, and appropriate respiratory protection.

• Personal Protective Equipment: Protective gloves (nitrile, neoprene), safety goggles, protective clothing, NIOSH-approved dust mask.

• Hygiene: Wash hands thoroughly after handling; Do not eat, drink, or smoke when using.

• Storage: Store in tightly closed containers in dry conditions; Protect from moisture; Keep away from acids and oxidizing agents.

• Spill Response: Avoid dust generation; Vacuum or wet-sweep; Place in closed containers.

• Disposal: Dispose of in accordance with local, regional, and national regulations.

LEGAL DISCLAIMER:

The information provided in this document is based on our current knowledge and experience and is presented in good faith. However, as all conditions of use are beyond our control, this document does not constitute a binding specification or warranty. This Technical Data Sheet is for informational purposes only. Users are responsible for testing suitability for their own applications. For complete safety, storage, handling, transportation, waste, and regulatory compliance information, please refer to the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier.