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Ethylene Diamine Tetra Acetic Acid, Edetic Acid, Versene, Chelating Agent, EDTA, 60-00-4

Ethylene Diamine Tetra Acetic Acid, Edetic Acid, Versene, Chelating Agent, EDTA, 60-00-4

Basic Properties

  • Chemical Formula: C10H16N2O8

  • CAS Number: 60-00-4

  • Molecular Weight: 292.24 g/mol

  • Appearance: White crystalline powder

  • Solubility: Slightly soluble in water (about 0.5 g/L at 25 °C)

  • pH (1% solution): 4.0–5.0

  • Melting Point: 237 °C

  • Density: 0.86 g/cm³

  • Storage Conditions: 2–8 °C

Structural Characteristics

  • Belongs to the polyamino carboxylic acid group.

  • Contains multiple -COOH and -NH2 groups.

  • Strong ability to bind metal ions, forming stable complexes.

Applications

  • Water Treatment: Prevents scale formation by binding calcium and magnesium ions.

  • Detergents and Cleaning Agents: Improves cleaning efficiency by sequestering metal ions.

  • Cosmetics: Stabilizes formulations and prevents oxidation.

  • Food Industry: Preserves color, taste, and texture; extends shelf life.

  • Pharmaceuticals: Used as an anticoagulant in blood samples.

  • Agriculture: Enhances plant access to essential nutrients.

  • Textiles and Paper: Supports bleaching processes and prevents catalytic damage.

  • Electronics and Metal Plating: Assists in copper deposition for printed circuit boards.

  • Industrial Use: Applied in coal plants, oil platforms, and polymer production as a cleaning or stabilizing agent.

Other Names

  • Ethylenediaminetetraacetic Acid

  • Edetic Acid

  • Versene

  • Chelating Agent / Sequestering Agent

Major Types of EDTA and Their Uses

Type Chemical Form CAS Number Key Applications
EDTA (Free Acid) Ethylenediaminetetraacetic acid 60-00-4 Used in analytical chemistry, laboratory buffers, and as a base compound for preparing salts.
Disodium EDTA (Na2EDTA) Disodium dihydrogen ethylenediaminetetraacetate 139-33-3 Common in cosmetics, food preservation, and pharmaceuticals; stabilizes formulations and prevents oxidation.
Tetrasodium EDTA (Na4EDTA) Tetrasodium ethylenediaminetetraacetate 64-02-8 Widely used in detergents, cleaning agents, and water treatment due to higher solubility and alkaline nature.
Calcium Disodium EDTA (CaNa2EDTA) Calcium disodium ethylenediaminetetraacetate 62-33-9 Medical use in chelation therapy for heavy metal poisoning (e.g., lead).
DTPA (Diethylenetriaminepentaacetic Acid) Extended chelating agent related to EDTA 67-43-6 Used in nuclear medicine imaging and industrial cleaning where stronger chelation is required.
HEDTA (Hydroxyethyl-EDTA) Hydroxyethyl ethylenediaminetriacetic acid 140-01-2 Applied in agriculture and textile processing, especially for micronutrient delivery.

Key Application Areas

  • Water Treatment: Na4EDTA is preferred for preventing scale and binding Ca²⁺/Mg²⁺ ions.

  • Cosmetics & Personal Care: Na2EDTA stabilizes creams, shampoos, and lotions by preventing metal-catalyzed degradation.

  • Food Industry: Na2EDTA acts as a preservative, maintaining color and flavor stability.

  • Pharmaceuticals: CaNa2EDTA is used in chelation therapy for lead poisoning; Na2EDTA serves as an anticoagulant in blood samples.

  • Agriculture: HEDTA and EDTA salts improve micronutrient availability to plants.

  • Industrial Cleaning & Detergents: Na4EDTA enhances cleaning efficiency by sequestering metal ions.

  • Textiles & Paper: EDTA salts prevent catalytic damage during bleaching and improve brightness.

Risks and Considerations

  • Safety: EDTA salts are generally safe at regulated concentrations but can cause toxicity if misused, especially in medical applications.

  • Environmental Impact: EDTA is persistent in the environment; wastewater treatment plants must manage its disposal carefully.

  • Regulatory Limits: Food and pharmaceutical use is strictly controlled, with maximum allowable concentrations set by agencies like FDA and EFSA.

BASF PRODUCTS:

Chelating Agents

  • Trilon® BS Ethylenediaminetetra acetic acid (EDTA) Powder approx. 99 approx. 2.8 approx. 820
  • Trilon® BS Powder Powder approx. 99 approx. 2.5––
  • Trilon® BD Disodium salt of EDTA, dihydrate Powder ≥ 89 approx. 4.5 approx. 950
  • Trilon® B Liquid Tetrasodium salt of EDTA Liquid approx. 40 approx. 11.5–approx. 1.31
  • Trilon® B Powder Tetrasodium salt of EDTA, tetrahydrate Powder approx. 87 approx. 11.5 approx. 700
  • Trilon® BX Liquid Tetrasodium salt of EDTA, pure form Liquid approx. 40 approx. 11.5–approx. 1.28
  • Trilon® BX Powder Powder approx. 84 approx. 11.2 approx. 845
  • Trilon® D Liquid Trisodium salt of Hydroxyethyl ethylenediaminetriacetic acid (HEDTA) Liquid approx. 40 approx. 11.5–approx. 1.26
  • Trilon® M Liquid Trisodium salt of Methylglycine diacetic acid (MGDA) Liquid approx. 40 approx. 11.0–approx. 1.30
  • Trilon® M EcoBalanced Liquid approx. 40 approx. 11.0–approx. 1.30
  • Trilon® M Max EcoBalanced Gran Solid approx. 81 approx. 11.4 approx. 790

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