Croscarmellose Sodium, Cross linked cellulose gum, 74811-65-7

Croscarmellose Sodium, Cross linked cellulose gum, 74811-65-7

CAS: 74811-65-7

Croscarmellose Sodium. This compound is a cross-linked polymer of carboxymethylcellulose sodium and is commonly used as a superdisintegrant in pharmaceutical formulations to improve drug dissolution and bioavailability

Here are some physical and chemical properties of croscarmellose sodium:

• Appearance: White or off-white, free-flowing powder

• Solubility: Practically insoluble in acetone, anhydrous ethanol, and toluene; swells rapidly in water to form a gel-like substance2

• pH Range: 5.0-7.03

• Melting Point: Greater than 205°C (decomposes)

• Density: Bulk density of 0.48 g/cm³3

• Odor: Odorless

Croscarmellose sodium is known by several other names, including:

• Cross-linked sodium carboxymethyl cellulose

• Cross-linked sodium CMC

• Cross-linked cellulose gum

• Croscarmellose

• Croscarmellose cellulose

• Croscarmellose sodium silicon dioxide

• Croscarmellose sodium USP

• Croscarmellose sodium BP

• Croscarmellose sodium EP

• Croscarmellose sodium NF

Croscarmellose sodium doesn't have widely recognized folk names. It's primarily known by its scientific and industry names, such as:

• Cross-linked sodium carboxymethyl cellulose

• Cross-linked cellulose gum

These names reflect its chemical structure and its use in various industries.

These names reflect its chemical structure and its use in various industries

Croscarmellose sodium is primarily used as a superdisintegrant in pharmaceutical formulations, promoting the rapid breakup of tablets and capsules in the gastrointestinal tract

Croscarmellose sodium is widely used in various industries due to its unique properties. Here are some common applications:

1. Pharmaceutical Industry: It is primarily used as a superdisintegrant in tablet formulations to enhance the dissolution and bioavailability of active pharmaceutical ingredients (APIs). This helps tablets break down quickly in the gastrointestinal tract.

2. Food Industry: It is used as an emulsifier and stabilizer in food products, where it is known by the E number E468. It helps improve the texture and stability of food items.

3. Cosmetics and Personal Care: It is used in cosmetics and personal care products as a thickening agent and stabilizer. It helps improve the consistency and shelf life of products like lotions, creams, and shampoos.

4. Agriculture: It is used in agricultural formulations as a dispersant and stabilizer for pesticides and herbicides, ensuring even distribution and effectiveness.