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Xylo Oligo Saccharide, Xylooligosaccharide, XOS, 87-99-0

Xylo Oligo Saccharide, Xylooligosaccharide, XOS, 87-99-0

XYLO-OLIGOSACCHARIDES (XOS) 

Product Name: Xylo-Oligosaccharides
Common Name: XOS, Xylo-Oligosaccharide
CAS Number: 87-99-0
EC Number (EINECS): 201-788-0
Molecular Formula: C₅H₁₂O₅ (monomer)
Chemical Class: Prebiotic dietary fiber (oligosaccharide)
Source: Xylan fraction from plant fibers (corncob, bamboo, hardwoods, wheat bran, rice husks)

SECTION 1: PRODUCT IDENTIFICATION AND DEFINITION

Parameter Information
Product Name Xylo-Oligosaccharides (XOS)
Other Names Xylo-Oligosaccharide, Xylo Oligo Saccharide, Xylooligosaccharide, XOS, Corn Xylo-Oligosaccharide, Organic Prebiotic Xylooligosaccharides, Preticx
Source Xylan fraction from plant fibers (corncob, bamboo, hardwood, wheat bran, rice husks, cottonseed hulls)
CAS Number 87-99-0
EC Number (EINECS) 201-788-0
Molecular Formula (Monomer) C₅H₁₂O₅
Molecular Weight (Monomer) 152.15 g/mol
Chemical Class Oligosaccharide, prebiotic dietary fiber
Appearance White to light yellow powder or light amber liquid
Odor Slight characteristic, mildly sweet
Taste Mildly sweet (approximately 30-40% sweetness of sucrose)
Physical State (20°C) Solid (powder) or liquid (syrup)
Allergen Status Hypoallergenic (dairy-free, soy-free, gluten-free)

SECTION 2: CHEMICAL COMPOSITION AND STRUCTURE

2.1. Chemical Structure

Parameter Information
Chemical Name Xylo-Oligosaccharides (β-1,4-xylan oligomers)
Structural Type Linear or branched chains of xylose units linked by β-(1→4) glycosidic bonds
Degree of Polymerization (DP) 2 – 10 units
Glycosidic Linkage β-(1→4) linkage between xylose units
Sugar Composition Xylose (C5 sugar)
Unique Feature C5 structure (pentose), fundamentally different from C6-based prebiotics (FOS, GOS)

2.2. Types of XOS

Type Description Purity
XOS Powder (95%) High-purity white powder ≥ 95%
XOS Powder (70%) Standard purity powder ≥ 70%
XOS Liquid (70%) Light amber syrup ≥ 70%

2.3. XOS Grade Specifications

Grade XOS Content (DP 2-7) Application
XOS-95P ≥ 95% High-end supplements, pharmaceuticals
XOS-70P ≥ 70% Food and beverage applications
XOS-70L ≥ 70% (liquid) Beverages, syrups, liquid formulations
XOS-50P ≥ 50% Animal feed, pet food

SECTION 3: PHYSICAL PROPERTIES

Property Value (Powder) Value (Liquid)
Appearance White to light yellow powder Light amber liquid
XOS Content ≥ 70% or ≥ 95% ≥ 70%
Moisture Content ≤ 5% 25-30%
Total Solids ≥ 95% ≥ 70%
pH (10% solution) 4.0 – 5.5 4.0 – 5.5
Solubility Highly soluble in water Completely soluble
Bulk Density 0.4 – 0.6 g/cm³ N/A
Particle Size 80 – 200 mesh N/A
Viscosity Low Low
Taste Mildly sweet (30-40% of sucrose) Mildly sweet
Odor Slight characteristic Slight characteristic
Hygroscopicity Moderate Moderate

SECTION 4: CHEMICAL AND NUTRITIONAL PROPERTIES

4.1. Nutritional Profile (per 100g, powder)

Parameter Value
Total Calories 1.5 – 2.0 kcal/g (approximately 150-200 kcal/100g)
Total Carbohydrate 95-98%
Dietary Fiber Content 85-95% (as prebiotic fiber)
Xylose (Free) < 3%
Moisture ≤ 5%
Ash Content ≤ 3%
pH (10% solution) 4.0 – 5.5

4.2. Purity and Composition Specifications

Parameter Specification (95% grade) Specification (70% grade)
XOS Content (DP 2-7) ≥ 95% ≥ 70%
DP2 (Xylobiose) 35-45% 25-35%
DP3 (Xylotriose) 20-30% 15-25%
DP4-7 (Higher Polymers) 25-40% 20-30%
Xylose (Monomer) < 1.5% < 5%
Ash ≤ 0.5% ≤ 3%

SECTION 5: PREBIOTIC PROPERTIES

5.1. Prebiotic Classification

Parameter Description
Definition Selectively fermented ingredient that allows specific changes in the composition and/or activity of the gastrointestinal microbiota that confer benefits on host well-being and health
Key Feature Super prebiotic – Highly selective for Bifidobacteria
Fermentation Rate Rapidly fermented by gut microflora
Fermentation Site Primarily the proximal colon
Primary Fermenters Bifidobacterium spp., Lactobacillus spp.
Unique Property C5 structure (pentose) fundamentally different from C6 prebiotics (FOS, GOS)

5.2. Prebiotic Selectivity

Microorganism Effect
Bifidobacterium spp. Strongly stimulated (selective proliferation)
Lactobacillus spp. Stimulated
E. coli Inhibited
Clostridium Inhibited
Bacteroides Minimal effect

SECTION 6: HEALTH BENEFITS

Benefit Description
Selective Prebiotic Activity Selectively stimulates Bifidobacteria and Lactobacilli; inhibits harmful bacteria (E. coli, Clostridium)
Mineral Absorption Enhances absorption of calcium, magnesium, iron, zinc, and other minerals
Gut Health Creates a healthy intestinal environment with beneficial bacteria; reduces digestive disorders and bloating
Blood Sugar Control Clinical studies show improvements in blood glucose levels
Lipid Metabolism Improves serum lipid profiles (cholesterol, triglycerides)
Immune Function Beneficial changes in immune markers; supports immune system function
Anti-inflammatory Reduces negative fermentation; decreases energy loss from fermentation
Weight Management Supports weight control; used in weight-loss foods
Anti-aging Used in anti-aging food applications
Bone Health Enhanced calcium and magnesium absorption supports bone health

6.2. Clinical Study Findings

Study Area Findings
Blood Glucose Improvements in blood glucose levels
Blood Lipids Improvements in serum lipid profiles
Digestive Health Significant digestive health benefits
Immune Markers Beneficial changes in immune markers
Mineral Absorption Enhanced calcium, magnesium, iron, and zinc absorption

SECTION 7: APPLICATION AREAS

7.1. Food and Beverage Industry

Application Function
Nutritional and Diet Products Prebiotic fiber enrichment
Dry Mix Products Powder mixes for beverages, meal replacements
Dietary Supplements Capsules, tablets, sachets, prebiotic formulations
Granola Bars Fiber enrichment; prebiotic benefits
Cookies and Biscuits Fiber addition; reduced sugar; prebiotic benefits
Dairy Products Prebiotic enrichment; supports probiotic activity
Beverages Soluble prebiotic fiber; functional drinks
Desserts Fiber enrichment; sugar reduction
Weight-Loss Foods Low-calorie fiber; satiety promotion
Anti-Aging Foods Gut health; mineral absorption
Bakery Products Moisture retention; fiber enrichment
Confectionery Sugar reduction; prebiotic benefits

7.2. Animal Nutrition

Application Function
Animal Feed (Swine) Gut health; antibiotic alternative; growth promotion
Poultry Feed Gut microbiota modulation; improved feed efficiency
Pet Food Prebiotic fiber; digestive health support
Aquaculture Gut health; disease resistance

7.3. Pharmaceuticals and Nutraceuticals

Application Function
Prebiotic Supplements Gut health; microbiome modulation
Synbiotics Combined with probiotics
Mineral Supplementation Enhances mineral absorption (calcium, magnesium, iron, zinc)
Functional Foods Health-promoting ingredient

SECTION 8: QUALITY SPECIFICATIONS (FOOD GRADE)

8.1. XOS Powder (95% Grade)

Parameter Specification
Appearance White to light yellow powder
XOS Content (HPLC, DP 2-7) ≥ 95.0%
Moisture ≤ 5.0%
pH (10% solution) 4.0 – 5.5
Ash Content ≤ 0.5%
Protein ≤ 0.5%
Free Xylose ≤ 1.5%
Total Plate Count ≤ 1,000 CFU/g
Yeast and Mold ≤ 50 CFU/g
Salmonella spp. Negative in 25g
Escherichia coli Negative in 10g
Heavy Metals (as Pb) ≤ 5 ppm
Lead (Pb) ≤ 1 ppm
Arsenic (As) ≤ 1 ppm
Mercury (Hg) ≤ 1 ppm
Cadmium (Cd) ≤ 1 ppm

8.2. XOS Powder (70% Grade)

Parameter Specification
Appearance White to light yellow powder
XOS Content (HPLC, DP 2-7) ≥ 70.0%
Moisture ≤ 5.0%
pH (10% solution) 4.0 – 5.5
Ash Content ≤ 3.0%
Free Xylose ≤ 5.0%
Total Plate Count ≤ 5,000 CFU/g
Yeast and Mold ≤ 100 CFU/g

8.3. XOS Liquid (70% Grade)

Parameter Specification
Appearance Light amber liquid
XOS Content ≥ 70.0%
Total Solids ≥ 70.0%
pH 4.0 – 5.5
Brix 70-75°
Color ≤ 200 ICUMSA
Heavy Metals ≤ 10 ppm

SECTION 9: MICROBIOLOGICAL SPECIFICATIONS

Parameter Specification (95% Grade)
Total Aerobic Mesophilic Bacteria ≤ 1,000 CFU/g
Yeast and Mold ≤ 50 CFU/g
Salmonella spp. Negative in 25g
Escherichia coli Negative in 10g
Staphylococcus aureus Negative in 1g
Coliforms ≤ 10 CFU/g
Enterobacteriaceae ≤ 10 CFU/g

SECTION 10: TYPICAL DOSAGE

Application Recommended Dosage
Daily Supplementation (Adults) 0.5 – 4.0 g/day
Digestive Health 0.5 – 2.0 g/day
Prebiotic Support 1.0 – 3.0 g/day
Mineral Absorption 1.0 – 4.0 g/day
Beverages 0.5 – 2.0% of formulation
Dairy Products 0.5 – 2.0% of formulation
Bakery Products 0.5 – 3.0% of formulation
Granola Bars 1.0 – 3.0% of formulation
Infant Formula 0.1 – 0.4 g/100 mL (as per regional regulations)
Animal Feed 0.05 – 0.2% of feed
Synbiotic Products 0.5 – 2.0 g/day with probiotics

SECTION 11: STORAGE AND SHELF LIFE

Parameter Information
Storage Conditions Cool (15-25°C), dry, well-ventilated area
Container Requirements Tightly closed, original packaging
Protect From Moisture, heat, direct sunlight
Shelf Life (Powder) 24-36 months (unopened original packaging)
Shelf Life (Liquid) 18-24 months (unopened original packaging)
Stability Note Stable at room temperature; store in airtight containers; avoid freezing (liquid may crystallize)

SECTION 12: PACKAGING OPTIONS

Packaging Type Quantity Material
Aluminum foil bag 1-5 kg Laminated aluminum
PE-lined kraft paper bag 10-25 kg Kraft paper + PE
Plastic pail 20-25 kg HDPE
Fiber drum 25-50 kg HDPE + PE liner
Big-Bag 500-1000 kg Polypropylene (with PE liner)
Plastic drum (Liquid) 200-250 kg HDPE (food grade)
IBC Tote (Liquid) 1000-1400 kg HDPE (food grade)

SECTION 13: SAFETY AND HEALTH INFORMATION

GHS Classification (Bulk Powder)

Hazard Class Category
Not classified as hazardous

Hazard Statements

Code Statement
None Not classified as hazardous

Precautionary Statements

Code Statement
P261 Avoid breathing dust
P280 Wear protective gloves/eye protection
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do; continue rinsing

SECTION 14: TOXICOLOGICAL INFORMATION

Parameter Value
Oral LD50 (Rat) > 5,000 mg/kg
Skin Irritation Non-irritant
Eye Irritation Mild irritant
Skin Sensitization Non-sensitizer
Carcinogenicity Not classified
Mutagenicity Negative in standard tests
Allergen Status Hypoallergenic; generally well tolerated
GI Tolerance Well tolerated at recommended doses (0.5-4.0 g/day); minimal GI discomfort
GRAS Status Generally Recognized as Safe

SECTION 15: REGULATORY STATUS

Region / Authority Status
European Union Approved as novel food ingredient; prebiotic
USA (FDA) GRAS (Generally Recognized as Safe)
EFSA Approved; prebiotic health claims recognized
China Approved as food ingredient and prebiotic
Japan Approved as food ingredient; FOSHU recognized
Turkey Approved as food ingredient
CODEX Alimentarius Recognized as dietary fiber

SECTION 16: TRANSPORT INFORMATION

Parameter Information
UN Number Not regulated (not dangerous goods)
Hazard Class Not applicable
Packing Group Not applicable
ADR/RID Not regulated
IMDG Code Not regulated
IATA (Air) Not regulated
Marine Pollutant No

SECTION 17: FIRE-FIGHTING MEASURES

Parameter Information
Fire Hazard Combustible organic powder
Suitable Extinguishing Media Water spray (mist), CO₂, dry chemical powder
Specific Hazards When heated, emits CO, CO₂
Decomposition Products CO, CO₂
Protective Equipment Self-contained breathing apparatus (SCBA), full protective clothing

SECTION 18: ACCIDENTAL SPILLAGE AND CLEANUP

Parameter Information
Personal Protection Nitrile gloves, protective goggles, dust mask (N95)
Cleaning Methods Sweep or vacuum; avoid dust generation. For liquid, absorb with inert material.
Environmental Precautions Prevent entry into drains, soil, and surface waters
Waste Disposal According to local regulations; landfilling at licensed facilities

SECTION 19: OTHER NAMES AND SYNONYMS

Type Name
Turkish Names Ksilo Oligo Sakkarit, Xylo Oligo Sakkarit, Xylo-oligosakkarit, XOS
English Names Xylo-Oligosaccharides, Xylo-Oligosaccharide, Xylooligosaccharide, XOS
Common Abbreviations XOS
CAS Number 87-99-0
EC Number 201-788-0
Commercial Names Preticx, Corn Xylo-Oligosaccharide, Organic Prebiotic Xylooligosaccharides

SECTION 20: SUMMARY AND CRITICAL NOTES

Product Summary

Parameter Value
Product Xylo-Oligosaccharides (XOS)
CAS Number 87-99-0
Appearance White to light yellow powder or light amber liquid
XOS Content (Powder 95%) ≥ 95%
XOS Content (Powder 70%) ≥ 70%
XOS Content (Liquid 70%) ≥ 70%
Sweetness 30-40% of sucrose
Calories 1.5-2.0 kcal/g
Primary Function Super prebiotic dietary fiber

Critical Notes

  • Super Prebiotic: XOS is recognized as a "super prebiotic" with exceptional selectivity for Bifidobacteria; it is 10-20 times more potent than FOS in some studies.

  • C5 Structure: XOS is based on pentose (C5) sugars, fundamentally different from C6-based prebiotics (FOS, GOS, inulin), giving it unique fermentation characteristics.

  • High Selectivity: XOS selectively promotes beneficial bacteria (BifidobacteriumLactobacillus) while inhibiting harmful bacteria (E. coliClostridium).

  • Mineral Absorption: Enhances absorption of calcium, magnesium, iron, zinc, and other minerals through increased mineral solubility in the colon.

  • Low Effective Dose: Effective at lower doses (0.5-4.0 g/day) compared to other prebiotics (FOS typically requires 5-15 g/day).

  • Excellent Stability: Stable at high temperatures (up to 200°C) and across a wide pH range (2.5-8.0), making it suitable for various food processing conditions.

  • Mild Sweetness: Clean, mild sweetness (30-40% of sucrose) with no off-taste; ideal for sugar reduction formulations.

  • Health Benefits: Clinically proven to improve blood glucose, serum lipids, digestive health, immune markers, and mineral absorption.

  • Minimal GI Discomfort: Well tolerated at recommended doses (0.5-4.0 g/day) with minimal gastrointestinal side effects compared to other prebiotics.

  • Versatile Applications: Used in nutritional products, dietary supplements, granola bars, cookies, biscuits, dairy, beverages, desserts, weight-loss foods, anti-aging foods, and animal nutrition.

  • Commercial Availability: Available in powder (70% and 95%) and liquid (70%) grades to suit various applications.

IMPORTANT DECLARATION: This Technical Data Sheet (TDS) is for informational purposes only and has been prepared based on available technical data. The user is responsible for determining the product's suitability for their specific application and for complying with all local, national, and international regulations. For complete safety, storage, use, transport, waste, and regulatory compliance information, refer to the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier.

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