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Caprylic Triglyceride, Capric Triglyceride, MCT Yağı, Orta Zincirli Trigliserit, MCT Oil, 73398-61-5, 65381-09-1

Caprylic Triglyceride, Capric Triglyceride, MCT Yağı, Orta Zincirli Trigliserit, MCT Oil, 73398-61-5, 65381-09-1

CAPRYLIC/CAPRIC TRIGLYCERIDE (MCT OIL)

SECTION 1: PRODUCT IDENTITY AND CHEMICAL IDENTIFICATION

Parameter Information
Product Name Caprylic/Capric Triglyceride
Common Names MCT Oil, Medium Chain Triglycerides, MCT, Fractionated Coconut Oil
Other Names Medium Chain Triglyceride Oil, Caprylic/Capric Glycerides, MCT Powder
CAS Number 73398-61-5 (general MCT mixture)
CAS Number 65381-09-1 (caprylic/capric triglyceride)
Molecular Weight Variable (mixture; ~500-600 g/mol)
Chemical Class Medium Chain Triglycerides (MCT)
Main Fatty Acids Caprylic Acid (C8:0), Capric Acid (C10:0)
Source Coconut oil, palm kernel oil (by fractionation)
Appearance (Liquid) Clear, colorless to pale yellow liquid
Appearance (Powder) White to cream-colored, free-flowing powder
Odor and Taste Neutral; odorless and tasteless

Note: MCT oil is a mixture of triglycerides formed from medium-chain fatty acids (6-12 carbon atoms), primarily caprylic acid (C8:0) and capric acid (C10:0), with glycerol. It is typically obtained by fractionation of coconut oil or palm kernel oil. Due to its unique metabolic pathway compared to long-chain triglycerides (LCT), it stands out as a rapid energy source and is widely used in ketogenic diets, sports nutrition, medical nutrition, and cosmetics.

SECTION 2: CHEMICAL STRUCTURE

General Structure:

    CH₂—O—CO—(CH₂)₆—CH₃
         |
    CH—O—CO—(CH₂)₆—CH₃
         |
    CH₂—O—CO—(CH₂)₈—CH₃

    Caprylic Acid (C8:0) - CH₃(CH₂)₆COOH
    Capric Acid (C10:0) - CH₃(CH₂)₈COOH

    Caprylic/Capric Triglyceride
    (Medium Chain Triglyceride - MCT)

Simplified Structure:

    Glycerol + 3 Medium Chain Fatty Acids → Triglyceride

    (Esterification of C8:0 and C10:0 fatty acids with glycerol)
Parameter Description
Molecular Structure Glycerol + 3 medium-chain fatty acids
Fatty Acids Caprylic acid (C8:0), Capric acid (C10:0)
Ester Bonds 3 ester bonds (glycerol + fatty acids)
Saturation Highly saturated (low iodine value)
Functional Groups Ester (-COO-)
Typical C8:C10 Ratio ~50-70% C8:0 / ~30-50% C10:0
InChI InChI=1S/C21H38O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20(23)26-19-21(24)25/h2-18H2,1H3
InChI Key Variable (mixture)

SECTION 3: PHYSICAL AND CHEMICAL PROPERTIES

Property Value (Liquid) Value (Powder) Test Method / Note
Appearance Clear, colorless – pale yellow liquid White – cream-colored powder Visual
Odor Odorless Odorless Olfactometric
Taste Tasteless Tasteless Sensory
Density (20°C) ~0.94 – 0.96 g/cm³ ~0.5-0.7 g/cm³ (bulk) ASTM D4052
Viscosity (25°C) 25 – 35 mPa·s - -
Smoke Point ~150 – 160 °C - -
Freezing Point <0°C (remains liquid) - -
Melting Point -5 to 0°C - DSC
Peroxide Value ≤1.0 meq O₂/kg ≤1.0 meq O₂/kg Titrimetric
Acid Value ≤0.2 mg KOH/g ≤0.2 mg KOH/g Titrimetric
Iodine Value ≤1.0 g I₂/100g ≤1.0 g I₂/100g Titrimetric
Water Solubility Insoluble Dispersible General Method
Oil Solubility Soluble Soluble General Method
Organic Solvent Solubility Soluble Soluble General Method
HLB Value ~5-6 - -
Refractive Index (n²⁰/D) 1.448 – 1.450 - ASTM D1218
Boiling Point >200°C - -
Flash Point >200°C - ASTM D93

SECTION 4: MCT COMPONENTS COMPARISON

Fatty Acid Carbon Count Double Bonds Melting Point MCT Ratio Properties
Caprylic Acid C8:0 None 16-17°C 50-70% Fastest ketone production, strongest antimicrobial
Capric Acid C10:0 None 31-32°C 30-50% Moderate ketone production, well-tolerated
Lauric Acid C12:0 None 44-46°C <5% Slower metabolism, LCT-like
Caproic Acid C6:0 None -3°C <2% Very low ratio, pungent odor

SECTION 5: METABOLIC PROPERTIES AND MECHANISM OF ACTION

Property Description
Rapid Digestion and Absorption Unlike long-chain triglycerides (LCT), MCTs are less dependent on bile salts and pancreatic lipase for digestion and absorption. They are rapidly hydrolyzed in the small intestine and transported directly to the liver via the portal vein as free fatty acids.
Rapid Energy Production Quickly enters mitochondria in the liver and undergoes beta-oxidation, rapidly converting to energy (ATP) or ketone bodies. This process is much faster than LCT transport through the lymphatic system.
Ketone Production MCTs are rapidly and efficiently converted to ketone bodies (beta-hydroxybutyrate, acetoacetate) in the liver, making them a key component of ketogenic diets. Ketones provide an alternative and efficient energy source for the brain and muscles.
Low Fat Storage Tendency Fatty acids from MCTs are primarily used for energy production and have a lower tendency to be stored in adipose tissue compared to LCTs.
Satiety and Thermogenic Effect MCT consumption may increase satiety and slightly elevate diet-induced thermogenesis (energy expenditure).
Antimicrobial Properties Medium-chain fatty acids (especially caprylic acid) in MCTs may exhibit antimicrobial effects against some bacteria, fungi, and viruses.

SECTION 6: HEALTH BENEFITS

Benefit Description Evidence Level
Rapid Energy Source Digestion and absorption are much faster than LCTs; transported directly to the liver via the portal vein Strong Clinical Evidence
Ketone Production Rapidly converted to ketone bodies in the liver, providing alternative fuel for the brain and muscles Strong Clinical Evidence
Weight Management Support May increase satiety, slightly elevate energy expenditure, and has low fat storage tendency Moderate Clinical Evidence
Cognitive Function Ketones provide alternative energy for the brain, especially when glucose metabolism is impaired (Alzheimer's, mild cognitive impairment) Moderate Clinical Evidence
Antimicrobial Effect MCT components (especially caprylic acid) may protect against harmful microorganisms Preclinical Evidence
Sports Performance Provides energy during endurance sports, preserves muscle glycogen Clinical Evidence

SECTION 7: APPLICATIONS AND USAGE

Industry Application Function Typical Usage Rate
Ketogenic Diet & Sports Nutrition Rapid energy source, ketone production Mental and physical performance support 5-30 g/day
Medical Nutrition Malabsorption syndromes, gallbladder issues Epilepsy (ketogenic diet), premature infant nutrition Clinical formulations specific
Food Supplements Energy powders, protein bars Meal replacement products 1-10 g MCT per serving
Cosmetics & Personal Care Emollient, moisturizer, carrier oil Light, non-greasy texture 1-10%
Pharmaceutical Excipient in drug formulations Capsule filling, solvent Variable
Animal Nutrition Energy supplement, digestive ease Feed formulations Variable
Aromatherapy Carrier oil Essential oil carrier 5-20%

SECTION 8: MCT POWDER FORM

Parameter Information
Production Method Spray drying of liquid MCT onto a carrier (acacia gum, starch, maltodextrin)
MCT Content Typically 50-70% MCT (depending on carrier)
Appearance White to cream-colored, free-flowing powder
Solubility Water-dispersible (cold/hot)
Advantages Ease of use in powdered supplements, sports nutrition products, instant beverage mixes
Applications Protein powders, coffee blends, smoothies, snack bars

SECTION 9: QUALITY SPECIFICATIONS

Parameter Specification Test Method
Appearance Clear, colorless to pale yellow liquid Visual
Odor and Taste Neutral; odorless and tasteless Sensory
Density (20°C) 0.940 – 0.960 g/cm³ ASTM D4052
Refractive Index (20°C) 1.448 – 1.450 ASTM D1218
Acid Value ≤0.2 mg KOH/g Titrimetric
Peroxide Value ≤1.0 meq O₂/kg Titrimetric
Iodine Value ≤1.0 g I₂/100g Titrimetric
Saponification Value 330 – 360 mg KOH/g Titrimetric
C8 Content ≥50-70% GC
C10 Content ≥30-50% GC
Total MCT Content ≥98% GC
Heavy Metals (Pb) ≤10 ppm ICP-MS
Arsenic (As) ≤2 ppm ICP-MS
Lead (Pb) ≤2 ppm ICP-MS
Microbiological Purity TAMC ≤10² CFU/g; TYMC ≤10¹ CFU/g USP <61>

SECTION 10: ALTERNATIVES AND COMPARISON

Alternative Comparison with MCT
Long-Chain Triglycerides (LCT - Vegetable Oils) Slower digestion and absorption; transported via lymphatic system. Inefficient for ketone production. More prone to fat storage compared to MCT.
Coconut Oil (Unrefined) Naturally contains 55-65% MCT, but also significant LCT. MCT oil is a purer, more concentrated MCT source obtained by fractionation.
Other Ketogenic Diet Fats (Butter, Tallow) High in LCT and cholesterol. Contribution to ketone production is much lower than MCT and provides slower energy.
Exogenous Ketone Salts/Esters Provide direct ketone bodies, instantly raising blood ketone levels. MCT supports the body's own ketone production (endogenous ketogenesis) as a precursor.

SECTION 11: TYPICAL DOSAGE AND USAGE

Application Recommended Daily Dose Notes
Ketogenic Diet (Beginner) 5-15 g/day Gradual increase recommended
Ketogenic Diet (Advanced) 15-30 g/day Divided into 2-3 meals
Sports Nutrition 10-20 g/day Before or after training
General Health Support 5-15 g/day With coffee, smoothies, yogurt
Weight Management 10-20 g/day For satiety
Cognitive Support 10-20 g/day With morning coffee
Topical (Cosmetics) 1-10% Creams, lotions, serums

SECTION 12: SAFETY AND HEALTH INFORMATION

GHS Classification:

Hazard Class Category
Not classified as hazardous substance

Signal Word: None

Hazard Pictograms: None

Side Effects:

Side Effect Frequency Management
Digestive discomfort (diarrhea, stomach cramps) Common (high dose) Gradual dose increase, take with meals
Nausea Less common Reduce dose, take with meals
Allergic reaction Rare Discontinue use, seek medical attention

Safety Notes:

  • Generally recognized as safe (GRAS)

  • Rapid consumption at high doses (especially in unaccustomed individuals) may cause temporary digestive discomfort

  • Gradual dose increase is recommended

  • Should be used under medical supervision during pregnancy and lactation

SECTION 13: FIRST AID MEASURES

Route of Exposure Action
Inhalation Vapor not expected in liquid form. If powder is inhaled, move to fresh air.
Skin Contact Wash with plenty of soap and water. Seek medical attention if irritation develops.
Eye Contact Rinse thoroughly with plenty of water for at least 15 minutes. Seek medical attention if irritation persists.
Ingestion Rinse mouth. Do NOT induce vomiting. Drink 1-2 glasses of water. Seek medical attention.

SECTION 14: STORAGE AND SHELF LIFE

Parameter Information
Storage Conditions (Liquid) Store in a cool (<25°C), dry, dark place in tightly closed containers. Protect from oxidation; nitrogen blanket may be applied for long-term storage.
Storage Conditions (Powder) Store in a cool, dry place, protected from moisture.
Temperature Limits 15-25°C (ideal); do not exceed 30°C
Light Protect from light (oxidation)
Container Requirements Tightly closed, moisture-resistant containers (HDPE, glass, stainless steel)
Incompatible Materials Light, heat, oxygen, strong oxidizing agents
Shelf Life (Liquid) 24-36 months (unopened original packaging)
Shelf Life (Powder) 18-24 months (unopened original packaging)
Signs of Degradation Darkening color, odor change (rancidity), cloudiness

SECTION 15: PACKAGING OPTIONS

Packaging Type Quantity / Capacity Material Application Area
HDPE Drum 5 kg, 10 kg, 25 kg, 200 kg HDPE Industrial, food, cosmetic
Glass Bottle 1 L, 5 L, 10 L Amber glass Laboratory, high purity
IBC Container 500 kg, 1000 kg HDPE (UV protected) Large-scale industrial supply
Aluminum Foil Bag (Powder) 1 kg, 5 kg, 10 kg, 25 kg Aluminum / PE Powder form
PE-Lined Kraft Bag (Powder) 10 kg, 25 kg Kraft paper / PE Powder form

SECTION 16: TRANSPORTATION INFORMATION

Parameter Information
UN Number Not applicable (not classified as dangerous substance)
Hazard Class Not applicable
Packing Group Not applicable
ADR/RID Not classified as dangerous goods
IMDG Code Not marine pollutant
IATA (Air) Not classified as dangerous goods; can be transported by air
Transport Temperature Ambient temperature; protect from heat, moisture, and light
Transport Precautions Light-proof, leak-proof packaging
Marine Pollutant No

SECTION 17: REGULATORY STATUS

Region / Authority Status
USA (FDA) GRAS (21 CFR 184.1505); Approved as food additive
European Union (EC) Approved as food supplement ingredient; Approved for reuse
Turkey Approved as food supplement and cosmetic ingredient; Ministry of Health approval required
EFSA Approved food ingredient
ECHA (REACH) Registered substance
TSCA (USA) Listed
California (Prop 65) Not listed
Halal Yes (coconut/palm source, Halal certified)
Kosher Yes (with certification)
Vegan Yes (plant-derived)

SECTION 18: OTHER NAMES AND SYNONYMS

Type Name
Turkish Names MCT Yağı, Orta Zincirli Trigliserit, Kaprilik/Kaprik Trigliserit
English Names MCT Oil, Medium Chain Triglycerides, Caprylic/Capric Triglyceride
Trade Marks MCT Oil, Pure MCT, Brain Octane, Ketogenic MCT
CAS Numbers 73398-61-5 (general); 65381-09-1 (caprylic/capric)
HS Code 1515.90

SECTION 19: SUMMARY TABLE

Property Value
CAS Number 73398-61-5 / 65381-09-1
Chemical Class Medium Chain Triglyceride (MCT)
Main Fatty Acids Caprylic Acid (C8:0), Capric Acid (C10:0)
Source Coconut oil, palm kernel oil
Appearance Clear, colorless liquid or white powder
Density (20°C) ~0.94 – 0.96 g/cm³
Odor and Taste Neutral; odorless and tasteless
Primary Benefit Rapid energy source, easy ketone production
Shelf Life 24-36 months
Storage Cool, dry, light-protected
GHS Classification Not hazardous
FDA Status GRAS
Halal / Kosher / Vegan Yes

SECTION 20: CRITICAL WARNINGS AND BEST PRACTICES

CRITICAL WARNINGS:

  1. Dose Increase: Rapid consumption at high doses (especially in unaccustomed individuals) may cause temporary digestive discomfort (diarrhea, stomach cramps). Gradual dose increase is recommended.

  2. Oxidation Sensitivity: MCT oil is sensitive to oxidation. Protect from light and heat.

  3. Water Insolubility: Liquid MCT oil is insoluble in water; emulsions or powder forms can be used.

  4. Caloric Value: MCT oil is high in calories (8.3 kcal/g). Should be considered when calculating daily caloric needs.

  5. Pregnancy / Lactation: Should be used under medical supervision during pregnancy and lactation.

  6. Diabetes: May affect blood sugar levels; diabetic patients should monitor blood sugar.

  7. CAS Difference: 73398-61-5 identifies the general MCT mixture, while 65381-09-1 identifies the specific caprylic/capric triglyceride.

BEST PRACTICE RECOMMENDATIONS:

  1. Starting Dose: Start with 1-2 teaspoons (5-10 mL), increase as tolerated.

  2. Gradual Increase: Increase dose gradually over 1-2 weeks.

  3. With Meals: Take with meals to reduce digestive discomfort.

  4. Coffee and Smoothies: Mix into coffee, smoothies, yogurt, or protein drinks.

  5. Emulsion: Thoroughly mix liquid MCT oil when adding to water-based beverages.

  6. Powder Form: Use powder form for easy mixing and portability.

  7. Storage: Store in a cool, dry, dark place.

  8. Oxidation Control: Keep tightly closed after opening to minimize air exposure.

LEGAL DISCLAIMER:

The information provided in this document is based on our current knowledge and experience and is presented in good faith. However, as all conditions of use are beyond our control, it does not constitute a binding specification or guarantee. This Technical Data Sheet is for informational purposes only. Users are responsible for testing suitability for their own applications and for complying with all local, regional, and national regulations. For complete safety, storage, use, handling, waste, and regulatory compliance information, please refer to the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier.

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