BIOTIN (VITAMIN B7 / VITAMIN H), Biotin (Vitamin B7 / Vitamin H), 58-85-5

BIOTIN (VITAMIN B7 / VITAMIN H), Biotin (Vitamin B7 / Vitamin H), 58-85-5

🧪 Biotin (Vitamin B7 / Vitamin H) – Technical & Nutritional Profile

📌 1. Product Description

• Product Name: Biotin (Vitamin B7 or Vitamin H)

• Chemical Formula: C₁₀H₁₆N₂O₃S

• CAS Number: 58-85-5

• EC Number: 200-399-3

• Molecular Weight: 244.31 g/mol

• Appearance: White crystalline powder

• Melting Point: 232–233 °C

• Solubility: Soluble in water

⚙️ 2. Physical & Chemical Properties

Physical Properties:

• Appearance: White crystalline powder

• Melting Point: 232–233 °C

• Solubility: Water-soluble

Chemical Properties:

• Chemical Formula: C₁₀H₁₆N₂O₃S

• Reactivity: Generally chemically inert; may react at high temperatures or with strong oxidizing agents

• pH Stability: Stable across a wide pH range

🧬 3. Biological Function

• Assists enzymes in breaking down fats, carbohydrates, and proteins

• Supports gene regulation and cell signaling

• Plays a role in energy metabolism and keratin production

• Essential for healthy skin, hair, and nails

🩺 4. Recommended Intake & Safety

• Adequate Intake (AI):

  • Adults (19+ years) & pregnant women: 30 mcg/day

  • Lactating women: 35 mcg/day

• Tolerable Upper Intake Level (UL):

  • No established UL due to lack of toxicity reports

  • High doses (10–300 mg) may interfere with lab tests (e.g., thyroid, vitamin D, troponin)

• FDA Warning (2017):

  • Biotin supplements may cause false lab results

  • Patients should inform healthcare providers of supplement use

🧴 5. Industrial Applications

🧾 6. Other Names

• Vitamin B7

• Vitamin H

• Coenzyme R

• Common Name: Biotin

🥗 7. Food Sources of Biotin

Animal-Based:

• Beef liver

• Cooked eggs

• Salmon

• Pork

• Avocados

Plant-Based:

• Sweet potato

• Nuts & seeds

• Legumes

• Whole grains

• Spinach

• Mushrooms

• Soybeans

⚠️ Biotin is water-soluble and sensitive to heat, light, and oxygen. Avoid overcooking vegetables to preserve vitamin content.

❓ 8. Scientific Notes & Research Summary

• No RDA (Recommended Dietary Allowance) due to insufficient data

• Biotin deficiency may cause hair loss, skin rash, brittle nails

• Supplementation may help only in deficient individuals

• Clinical studies are inconclusive for healthy populations

• Alopecia and other conditions may resolve spontaneously, not necessarily due to biotin

• Between 1999–2016, biotin supplement usage increased 30-fold