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Vitamin B5, Calcium-D-Pantothenate, Pantothenic Acid, Panthenol, Pantothenate, Dexpanthenol, Pantothenyl Alcohol, 137-08-6

Vitamin B5, Calcium-D-Pantothenate, Pantothenic Acid, Panthenol, Pantothenate, Dexpanthenol, Pantothenyl Alcohol, 137-08-6

Product Information: Calcium-D-Pantothenate

  • Chemical Name / Synonyms: D-Pantothenic acid hemicalcium salt, Pantothenic acid, Panthenol, Pantothenate, Dexpanthenol, Pantothenyl alcohol

  • Molecular Formula: C9H16O5N·½Ca

  • Molecular Weight: 238.27

  • CAS Number: 137-08-6

  • Appearance: White to off-white crystalline powder

  • Solubility: Soluble in water

  • pH (5% solution at 25°C): 6.8 – 8.0

  • Specific Rotation [α]20D: +25.0° to +27.5° (c=5% in H2O)

  • Melting Point: ~190°C

  • Loss on Drying (105°C): ≤ 5%

  • Culture Test Results:

    • Shoot culture: No deformities, active growth, no toxicity

    • Callus culture: No necrosis, active growth, no toxicity

Biological Importance of Vitamin B5

  • Water-soluble: Not stored in the body, must be consumed daily.

  • Energy metabolism: Essential component of Coenzyme A, enabling the conversion of carbohydrates, proteins, and fats into energy.

  • Hormone synthesis: Plays a key role in producing stress-related hormones such as cortisol.

  • Skin health: Supports cell regeneration, elasticity, and hydration. Widely used in skincare formulations.

Dietary Sources of Vitamin B5

  • Animal-based: Chicken breast, egg yolk, beef liver

  • Plant-based: Avocado, lentils, whole grains (oats, brown rice), broccoli

  • Note: Balanced diets generally provide sufficient amounts, but processed-food-heavy diets may increase deficiency risk.

Signs of Deficiency

  • Fatigue, headaches, muscle cramps

  • Depression, weakened immunity

  • Dry skin, hair loss

Daily Requirement

  • Adults: ~5 mg per day

  • Supplements: Found in multivitamins, B-complex formulations, and standalone B5 supplements.

Why It Matters

Vitamin B5 is indispensable for:

  • Energy production (via Coenzyme A)

  • Stress management (hormone regulation)

  • Skin health (hydration, elasticity, anti-aging support)

 

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