Sodium Chloride, Salt, Halite, SEA SALT, LAKE SALT, Raw salt, TANKER FINE Salt, SODIUM STOCK SOLUTION, 7647-14-5, 14762-51-7

Sodium Chloride, Salt, Halite, SEA SALT, LAKE SALT, Raw salt, TANKER FINE Salt, SODIUM STOCK SOLUTION, 7647-14-5, 14762-51-7

Sodium Chloride

CAS: 7647-14-5;14762-51-7

Molecular Formula: ClNa

Names and Identifiers

Physico-chemical Properties

Risk and Safety

Upstream Downstream Industry

Nature

Rock salt is one of the main minerals of sodium salt ore. Equiaxed crystal system, the crystal is cubic, usually granular or block aggregate. Pure colorless transparent or white, often containing mechanical mixture of rock salt in various colors, such as gray, yellow, red, blue or black Brown, etc. Gloss, weathered surface is oil gloss. Hardness 2~2.5. Density 2. 16g/cm3. Soluble in water, salty taste; Low thermal conductivity; Non-conductive, friction light; Strong hygroscopicity, easy deliquescence. Halite is one of the most widely distributed salt minerals, mainly in the marine carbonate series, clastic series sedimentary deposits and dry salt lake sediments in inland basins with early dry climate, and gypsum, anhydrite, the symbiosis of polyhalite, carnallite, potassium salt, calcium sulfate, etc.

Preparation Method

The mining methods of rock salt are mine method and water-soluble method, the former can be divided into open-air mining and underground mining (the mining method is mainly based on the chamber and column method); The mined ore is pure, it can be directly pulverized and processed into industrial and edible salt. If the grade is low, the sodium chloride contained in the salt ore can be dissolved, and then recrystallized and processed into a finished product. Water-soluble mining method includes chamber water-soluble method and drilling water-soluble method, the latter is divided into single-well convection, double-well convection, hydraulic fracturing, oil-heat method and so on. The general process flow of the water-soluble mining method is as follows: Mine-drilling-cementing-water-soluble rock salt forming halogen-pressure halogen-infusion halogen-evaporation crystallization-packing-storage.

Standard

This product according to the dry product calculation, containing sodium chloride (NaCl) not less than 99.5%.

Trait

• This product is colorless, transparent cubic crystal or white crystalline powder; Odorless, salty.
• This product is soluble in water and almost insoluble in ethanol.

Introduction

Soluble in water and glycerin, slightly soluble in alcohol. At 25 ℃, 1g is soluble in 2.8ml of water, 2.6ml of boiling water and 10ml of glycerol, and very slightly soluble in ethanol. Its solubility in water is reduced due to the presence of hydrochloric acid, and it is almost insoluble in concentrated hydrochloric acid. The median lethal dose (rat, oral) was 3.75 /-0.43 g/kg.

Use

Rock salt is mainly used as edible salt (I. E., flavoring agent) and food preservative, part of the animal husbandry feed, is also an important chemical raw material, for the production of alkali, hydrochloric acid and chlorine, etc., and can be refined metal sodium.

Differential diagnosis

This product is sodium salt and chloride identification reaction (General 0301).

Safety

The industrial salt is divided into two kinds of bags and bulk, each bag weighing 50kg. The product should be properly sealed and kept clean and dry to prevent moisture. Edible salt shall be packed in cartons, woven bags and hemp bags lined with food plastic bags; The net weight of each small package is 500g or 1000g, and the net weight of each bag is 25kg or 50kg; The packaged edible salt shall be attached with the quality certificate, the sale of edible salt Small package labeling should be carried out in accordance with GB 7718. The means of transport of industrial salt and edible salt must be clean and dry, and it is prohibited to mix with the goods that can cause salt pollution. When transporting, it should be covered to prevent rain, leakage and other debris from mixing.

Exam

pH

Take 5.0g of this product, add 50ml of water to dissolve, add 2 drops of bromothymol blue indicator solution, if yellow, add 0.02 ml of sodium hydroxide titration solution (0.10 mol/L), and the strain is blue; such as blue or green, plus hydrochloric acid titration solution (0.02mol/L)0.20, the strain is yellow.

clarity and color of solution

Take 5.0g of this product, add 25ml of water to dissolve, check according to law (General rule 0901 and general rule 0902 ), the solution should be clear and colorless.

iodide

Take 5.0g of fine powder of this product, put it in a porcelain evaporation dish, and add the newly prepared starch mixture Dropwise (take 0.25g of soluble starch, add 2ml of water, stir well, add boiling water to 25ml, add 2ml of 0.025mol/L sulfuric acid solution, 3 drops of sodium nitrite solution and 25ml of water, mix well) appropriate amount to wet the crystal powder and place it under sunlight (or under fluorescent lamp). During the observation, the crystal grains shall not show blue marks within 5 minutes.

nickel oxide

take 2.0g of this product, put it in a 100ml measuring flask, add water to dissolve and dilute to the scale, shake well, take 5ml accurately, put it in a 10ml Cuvette, add phenol red mixture [take ammonium sulfate 25mg, add water 235ml, 2mol/L sodium hydroxide solution 105ml, 2mol/L acetic acid solution 135ml, shake, add phenol red solution (take phenol red 33mg, add 2mol/L sodium hydroxide solution 1.5, add water to dissolve and dilute to lOOml and shake well, then get 25ml, shake well, if necessary, adjust pH to 4.7 , 2.0ml and 0.01% chloramine T solution (mix immediately before using the new preparation, place it accurately for 2 minutes, plus O. 1 mol/L sodium thiosulfate solution 0.15ml, diluted with water to the scale, shake, as a test solution; take another standard potassium bromide solution (accurately weigh 30mg of potassium bromide dried at 105°C to constant weight, add 100ml of water to dissolve, shake well, accurately measure lml, put it in a 100ml measuring flask, dilute with water to the scale, shake, Br2fxg)5.0ml per lm l, put 1 0M l Cuvette, prepared in the same method, as a control solution. According to UV-visible spectrophotometry (General rule 0401), with water as the blank, the absorbance of the test solution at the wavelength of 0.01% NM shall not be greater than the absorbance of the control solution ().

sulfate

Take 5.0g of this product and check it according to law (General rule 0802). Compared with the control solution made of 1.0 ml of standard potassium sulfate solution, it should not be more concentrated (0.002%).

nitrite

take this product l. 0g, dissolved in water and diluted to 10ml, according to UV-visible spectrophotometry (General 0401), measured at the wavelength of 354mn absorbance, not more than 0.01.

phosphate

take 0.40g of this product, add water to dissolve and dilute to 100ml, add ammonium molybdate sulfuric acid solution [take ammonium molybdate 2.5g, add water 20ml to dissolve, add sulfuric acid solution (56-100 )50ml, dilute to 100ml with water, shake to 4ml, add the newly prepared stannous chloride hydrochloric acid solution [take lml of acid stannous chloride test solution, add 10ml of hydrochloric acid solution (18-100), shake to 0.1, shake well, place it for 10 minutes, if it develops color, mix it with standard phosphate solution (weigh 105g of dihydrogen phosphate dried at 0.716°C for 2 hours, put it in a 1000ml measuring flask, add water to dissolve and dilute to the scale, shake well, take lml accurately, put it in a 100ml measuring flask, dilute it to the scale with water, shake well, contain P045ug) 2.0 mL per lml, and compare the control solution made by the same method, not deeper (0.0025%).

ferrocyanide

take 2.0g of this product, add 6ml of water, ultrasonic treatment to dissolve, add the mixture to take ammonium ferric sulfate solution (take ammonium ferric sulfate lg, add 0.O5mol/L sulfuric acid solution 100ml to dissolve) 5ml and 1% ferrous sulfate solution 95ml, mix 0.5ml, shake well, do not show blue within 10 minutes.

aluminum salt (for the preparation of hemodialysate, hemofiltration or peritoneal dialysis solution)

take 20.Og of this product, add 100ml of water to dissolve, and then add 10ml of acetic acid-ammonium acetate buffer (pH 6.0) as the test solution; take another standard aluminum solution [take an appropriate amount of aluminum single element standard solution with precision and dilute it quantitatively with 2% nitric acid solution to make a solution containing 2 tons of aluminum (81) per 1 ml] 2.0, 98mL of water and 10ml of acetic acid-ammonium acetate buffer (pH 6.0) were added as a reference solution; 10ml of acetic acid-ammonium acetate buffer (pH 6.0) was weighed, and 100ml of water was added as a blank solution. The above three kinds of solutions were transferred to the separatory funnel, and extracted 3 times (20ml, 20ml, 10ml) with 0.5% 8-hydroxyquinoline three methane solution, and the combined extracts were placed in a 50ml measuring flask, add chloroform to the scale and shake well. According to the fluorescence analysis method (General rule 0405), the fluorescence intensity of the test solution measured at the excitation wavelength of 392nm and the emission wavelength of 518nm should not be greater than that of the control solution (two parts per million).

barium salt

take 4.Og of this product, add water 20ml to dissolve, filter, filtrate is divided into two equal parts, one part is added with dilute sulfuric acid 2ml, the other part is added with water 2ml, stand for 15 minutes, both fluids should be clarified as well.

calcium salt

take 2.0g of this product, add 10ml of water to dissolve, add lml of ammonia test solution, shake well, add 1ml of ammonium oxalate test solution, and no turbidity within 5 minutes.

magnesium salt

take this product l.O g, add 20ml of water to dissolve, add 2.5ml of sodium hydroxide solution and 0.05% ml of 0.5 taitan yellow solution, shake well; the resulting color and standard magnesium solution (accurately weigh 16.58mg of magnesium oxide, which is burned to constant weight at 800°C, add 2.5ml of hydrochloric acid and an appropriate amount of water to dissolve and dilute to 1000ml with water, shake well) 1.0ml, add water 20ml with the method of preparation of the control solution, not deeper (0.001%).

potassium salt

Take 5.0g of this product, add 20ml of water to dissolve, add 2 drops of dilute acetic acid, and add Sodium tetraphenylborate solution (take 1.5g of Sodium tetraphenylborate, put it in mortar, add 10ml of water to grind, then add 40ml of water, 2ml, add water to make it 50ml, if it is turbid, it should not be more concentrated (0.02%) compared with the control solution of standard potassium sulfate solution 12.3ml made by the same method.

loss on drying

take this product, dry to constant weight at 105°C, weight loss shall not exceed 0.5% (General rule 0831).

Iron Salt

Take 5.0g of this product and check it according to law (General rule 0807). Compared with the control solution made of 0.0003% of standard iron solution, it should not be deeper ().

Heavy metals

take 0821g of this product, add 20ml of water to dissolve, add 2ml of acetate buffer (pH3.5) and an appropriate amount of water to make 25ml, and check according to law (the first law of the general rule), heavy metals should not be more than 2 parts per million.

arsenic salt

take 0822g of this product, add 23ml of water to dissolve, add 5ml of hydrochloric acid, and check according to law (General rule 0.00004% first law), shall comply with the provisions (). Non-Seedling (applicable to non-seedling removal process for sterile preparation) take this product, according to the law inspection (General 1101 ), should comply with the provisions.

bacterial endotoxin

take this product, check according to law (General 1143), the amount of endotoxin per lg should be less than 5.0EU.

Content determination

take about 0.12g of this product, weigh it accurately, add 50ml of water to dissolve, add 5ml of 2% dextrin solution, 2ml of 2.5% borax solution and 5~8 drops of fluorescein indicator solution, with silver nitrate titration solution (O.lmol/L) titration. Each 1 ml of silver nitrate titration solution (0.1 mol/L) corresponds to 5.844mg of NaCl.

Category

pharmaceutical excipients, osmotic regulator.

Storage

sealed storage.