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Iodine, Iodine crystals, Iodine solution, Prilled Iodine, Elemental Iodine, 7553-56-2, 12190-71-5

Iodine, Iodine crystals, Iodine solution, Prilled Iodine, Elemental Iodine, 7553-56-2, 12190-71-5

🧪 Iodine – CAS 7553-56-2

🔬 Basic Chemical Information

Property Value
CAS Number 7553-56-2
Chemical Name Iodine, Molecular Iodine, Diiodine
Molecular Formula I₂
Molecular Weight 253.81 g/mol
EC Number 231-442-4
Appearance Dark violet crystals or prilled beads
Odor Sharp, characteristic iodine smell
Solubility Slightly soluble in water; soluble in ethanol, chloroform, ether
Melting Point 113 °C
Boiling Point 184 °C
Density 4.93 g/cm³
Vapor Pressure 0.31 mmHg at 25 °C
pH (saturated sol.) ~5.4

⚙️ Sectoral Usage Table – CAS 7553-56-2

🏭 Sector ⚙️ Application 📌 Notes
Chemical Industry Reagent, catalyst, intermediate Used in organic synthesis and halogenation reactions
Pharmaceutical Tincture iodine, iodophor production, API synthesis Required for antiseptic formulations and iodine-based drugs
Laboratory Titration reagent, iodine value determination Used in redox reactions and analytical chemistry
Agriculture Feed additive, micronutrient Prevents iodine deficiency in livestock
Food Industry Iodized salt production Complies with WHO/FAO and Codex Alimentarius standards
Photography Film and developer chemistry Historical use in silver halide processing
Pigments/Dyes Iodine-based pigment synthesis Used in specialty colorants
Hygiene/Disinfection Raw material for povidone iodine Active iodine source in antiseptic production
Analytical Chemistry Starch test, solubility analysis Forms blue-violet complex with starch
Trade & Customs Export/import of technical iodine (USP/ACS grades) CAS 7553-56-2 required in customs and MSDS documentation

📋 Mandatory Usage Sectors – CAS 7553-56-2

🏭 Sector 📌 Mandatory Use Reason 📋 Regulatory or Technical Basis
Pharmaceutical Production API synthesis, antiseptic formulations USP/EP standards require pure iodine for tinctures and iodophors
Laboratory Analysis Titration, iodine number determination ISO and ASTM methods specify iodine as reference reagent
Food Additive Manufacturing Iodized salt production WHO/FAO and Turkish Food Codex mandate iodine content in table salt
Animal Feed Production Micronutrient additive Ministry of Agriculture regulations require iodine supplementation
Hygiene & Disinfection Povidone iodine manufacturing Formulation standards require elemental iodine as active source
Analytical Chemistry Starch testing, solubility profiling Standard methods use iodine for qualitative analysis
Trade & Customs Technical iodine classification CAS 7553-56-2 must be declared in customs and safety documentation

 

🔬 Chemical Identity

Property Value
CAS Number 12190-71-5
Chemical Name Iodine, Elemental Iodine
Molecular Formula I₂
Molecular Weight 253.81 g/mol
EC Number 231-442-4
SMILES II
InChIKey PNDPGZBMCMUPRI-UHFFFAOYSA-N

🌡️ Physical Properties

  • Appearance: Black to violet crystalline powder or granules

  • Crystal Structure: Monoclinic or orthorhombic (depending on grade)

  • Melting Point: ~113 °C

  • Boiling Point: ~184 °C

  • Solubility: Poor in water (0.03 g/100 mL); soluble in ethanol, ether, chloroform, acetone

  • Dielectric Constant: ~11.0 (ambient)

⚙️ Sectoral Applications – CAS 12190-71-5

🏭 Sector ⚙️ Application 📌 Notes
Chemical Synthesis Halogenation, catalyst, intermediate Used in organic reactions requiring high-purity iodine
Pharmaceutical API synthesis, iodine-based formulations Meets pharmacopoeia standards for iodine content
Laboratory Analytical reagent, iodine value testing Used in HPLC, LC-MS, and redox titrations
Electronics Semiconductor etching, iodine doping Applied in specialty materials and thin film processes
Food & Feed Micronutrient additive Used in fortified salt and animal feed (regulated use)
Disinfection Raw material for povidone iodine Serves as iodine source in antiseptic production
Customs & Trade Export/import of iodine granules CAS 12190-71-5 required in customs declarations and MSDS

📋 Regulatory & Mandatory Use

  • FDA Listings: 21 CFR 101.9, 104.20, 107.10, 107.100, 310.545, 582.80

  • UNII Code: 9679TC07X4

  • ATC Code: D08AG03 (Antiseptics)

  • EWG Food Score: 2–5 (depending on formulation)

This form of iodine is often preferred for high-purity applications, especially in pharmaceutical synthesis, analytical chemistry, and regulated feed additives. If you'd like, I can now prepare a bilingual comparison table between CAS 7553-56-2 and CAS 12190-71-5 for catalog or audit use 📄🔍.

 

🧾 Synonyms and Trade Names for CAS 12190-71-5

🧪 Synonym / Trade Name 📌 Context / Usage
Iodine General name for elemental iodine
Diatomic Iodine Structural reference (I₂ molecule)
Iodine Crystals or Liquid Commercial form description
Iodine Solution Standard Substance Analytical reagent grade
Iodine Test Solution (ChP) Chinese Pharmacopoeia reference
Iodine (JP15/USP) Japanese and US Pharmacopoeia grade
Iodine Base Raw material designation
HX968 Internal or catalog code used by suppliers
TIANFU-CHEM Iodine Supplier-specific trade name
Iodien German variant spelling
Iodide (I21-) (8CI,9CI) Registry variant (not to be confused with iodide ion)

Iodine

CAS: 7553-56-2;12190-71-5

Molecular Formula: I2

Names and Identifiers

Name Iodine
Synonyms iodine
iodien
Iodine
Iodine crystals
Iodine solution
TIANFU-CHEM Iodine
Iodine test solution
Iodide (I21-) (8CI,9CI)
Iodine,standard solution
Iodine Crystals or Liquid
Iodine test solution(ChP)
Iodine solution standard substance
CAS 7553-56-2
12190-71-5
EINECS 231-442-4
InChI InChI=1/I2/c1-2

Physico-chemical Properties

Molecular Formula I2
Molar Mass 253.81
Density 3.834g/cm3
Melting Point 114℃
Boling Point 184.3°C at 760 mmHg
Water Solubility 0.3 g/L (20℃)
Vapor Presure 0.49mmHg at 25°C
Refractive Index 1.788
Physical and Chemical Properties Purple-black scale crystals or platelets with metallic luster. Friable, with purple vapor. Has a special irritating odor.
melting point 113.5 ℃
boiling point 184.35 ℃
relative density 4.93(20/4 ℃)
solubility it is slightly soluble in water, and the solubility increases with the increase of temperature; insoluble in sulfuric acid; Soluble in organic solvents; Iodine is also soluble in chloride, bromide; More soluble in iodide solution; Soluble sulfur, selenium, ammonium and alkali metal iodide, aluminum, tin, titanium and other metal iodides.
Use Mainly used in the manufacture of iodide, used in the manufacture of pesticides, feed additives, dyes, iodine, test paper, drugs, etc For the preparation of equivalent solvent, determination of iodine value, calibration of sodium thiosulfate solution concentration, the solution can be used as disinfectant, photographic plate for iodine agent and thinning liquid preparation

Risk and Safety

Hazard Symbols Xn - Harmful
Harmful
N - Dangerous for the environment
Dangerous for the environment
Risk Codes R20/21 - Harmful by inhalation and in contact with skin.
R50 - Very Toxic to aquatic organisms
Safety Description S23 - Do not breathe vapour.
S25 - Avoid contact with eyes.
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. 
UN IDs UN 1759/1760

Upstream Downstream Industry

Raw Materials Sodium hydroxide
Hydrochloric acid
Downstream Products Sodium iodide
Potassium iodide
Sodium iodate
Potassium iodate
Potassium periodate
Calciumiodideanhydrous
Sodium periodate
3,5-Diiodosalicylic acid
Tetrachlorophthalic anhydride
Iodine pentoxide
Sodium iodate

Nature

blue-black phosphorus crystals or platelets with metallic luster. It is brittle and easy to sublimate, and its vapor is purple at room temperature, with spicy and stimulating smell. Melting point 113. 60 °c; Boiling point 185. 24 °c; d (solid, 25 °c) 4.93,d (liquid 120 °c) 960. Slightly soluble in water, soluble in chloroform, ethanol, benzene, carbon disulfide, carbon tetrachloride. Strong oxidant. Exposure to ammonia and acetylene can cause explosion. A strong reaction can occur with the reducing agent. Ignition is caused by contact with bromine pentafluoride, chlorine trifluoride, fluorine, metal powder, water, phosphorus, etc. A vigorous reaction occurred with acetaldehyde. Corrosive. By high heat decomposition, release of toxic smoke.

Preparation Method

  1. ion exchange method: the kelp was soaked twice with 13-15 times the amount of water, and the iodine content of the soaking solution was 0.5-0.55g/L. Because the soaking solution contains a lot of fucoidan and other impurities, need to add alkali to remove, add 36% ~ 40% liquid alkali, after fully stirred, make pH 12. Clarify more than 8H. The supernatant is sent to the acidification tank, hydrochloric acid is added to adjust the pH at 1.5~2, and then sent to the oxidation tank to oxidize with chlorine gas to free iodine, which is adsorbed by 717 ion exchange resin and desorbed by adding sodium sulfite, the obtained iodine-containing desorption solution is added with potassium chlorate and sulfuric acid to precipitate iodine. The crude iodine is heated to above 150 ° C., and then fused and refined by adding concentrated sulfuric acid. Waste iodine water passed through an ion exchange column was used to extract mannitol.
  2. air blowing method: the mother liquor of iodine-containing salt is added to hydrochloric acid for acidification, the pH is controlled at 1~2, and the solution is preheated to about 40 ℃, and sent to the oxidizer, at the same time, the appropriate amount of chlorine is introduced, the iodine ions in the feed liquid are oxidized into iodine molecules, and the oxidized liquid is sent to the blow-out tower, and the air preheated to 40 ° C is passed through the lower part of the blow-out tower, the iodine is blown out, and the iodine-containing air enters the absorption tower, is absorbed by the sulfur dioxide aqueous solution sprayed under the upper part of the tower, and is reduced to generate hydroiodic acid. When the concentration of the absorption solution reaches about 150g/L of iodine, it is sent to the iodine Analyzer. Under constant agitation, chlorine gas is slowly introduced to free iodine and precipitate, add concentrated sulfuric acid melt refined, cooling crystallization, crushing, iodine product.

Use

is the basic raw material for the manufacture of inorganic iodide and organic iodide, mainly used in medicine and health, for the manufacture of various iodine preparations, fungicides, disinfectants, deodorants, analgesics and antidotes of radioactive substances. It is a raw material for the production of pesticides, and it is also a feed additive for livestock. Industrial bacteriostatic agent for the synthesis of dyes, smoke extinguishing agents, photographic emulsion and cutting oil emulsion. Single-crystal prisms for the manufacture of electronic instruments, polarizers for optical instruments, and glass capable of transmitting infrared rays. For leather and special soaps. Iodine is a good catalyst for methylation, isomerization and dehydrogenation reactions in organic synthesis. It is also used as a separating agent for alkanes and alkenes. It is used as a stabilizer for Rosin, tall oil and other wood products. It is also used as a refining agent for high purity zirconium, titanium, hafnium, silicon and germanium.

Safety

rat oral LD50:14000mg/kg; Mouse oral LD50: 22000mg/kg. This product has a strong stimulating effect on the eyes, skin and mucous membranes. Human oral lethal dose is about 2~3G. Store in a cool, dry, well-ventilated non-combustible warehouse. Keep the container sealed. Protected from light. It is not allowed to be co-stored and mixed with ammonia and alkali substances. In the transport process to prevent rain, sun exposure. Handling and handling should be light. To prevent the rupture of the packaging bottle.

Introduction

Iodine is a chemical element with the chemical symbol I and atomic number 53. Iodine is a non-metallic element commonly found in nature in the oceans and soil. The following is a description of the nature, use, formulation and safety information of Iodine:

1. Nature:
-Appearance: Iodine is a blue-black crystal, common in solid state.
-Melting point: Iodine can directly change from solid to gaseous state under air temperature, which is called sub-limation. Its melting point is about 113.7 ° C.
-Boiling point: The boiling point of Iodine at normal pressure is about 184.3 ° C.
-Density: The density of Iodine is about 4.93g/cm³.
-Solubility: Iodine is insoluble in water, but soluble in some organic solvents such as alcohol, cyclohexane, etc.

2. Use:
-Pharmaceutical field: Iodine is widely used for disinfection and sterilization, and is commonly found in wound disinfection and oral care products.
-Food industry: Iodine is added as Iodine in table salt to prevent Iodine deficiency diseases, such as goiter.
-Chemical experiments: Iodine can be used to detect the presence of starch.

3. Preparation method:
- Iodine can be extracted by burning seaweed, or by extracting ore containing Iodine through chemical reaction.
-A typical reaction for preparing Iodine is to react Iodine with an oxidizing agent (such as hydrogen peroxide, sodium peroxide, etc.) to generate Iodine.

4. Safety Information:
- Iodine may be irritating to the skin and eyes at high concentrations, so you need to pay attention to the use of personal protective equipment, such as gloves and goggles, when handling Iodine.
- Iodine has low toxicity, but should avoid excessive intake of Iodine to avoid Iodine poisoning.
- Iodine can produce toxic Iodine hydrogen gas at high temperature or open flame, so avoid contact with flammable materials or oxidants.

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