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Capsicum Oleoresin, Capsicum Extract, Capsaicin Oleoresin, Dihydrocapsaicin, Paprika Oleoresin, Red Pepper Extract, Capsicum Resin, E165C, 8023-77-6

Capsicum Oleoresin, Capsicum Extract, Capsaicin Oleoresin, Dihydrocapsaicin, Paprika Oleoresin, Red Pepper Extract, Capsicum Resin, E165C, 8023-77-6

CAPSICUM OLEORESIN (OLEORESIN CAPSICUM)

PRODUCT IDENTIFIER INFORMATION

Parameter Information
Product Name Capsicum Oleoresin (Oleoresin Capsicum)
Chemical Name Oleoresin Capsicum
CAS Number 8023-77-6
Food Additive Code E165C
Molecular Formula (Capsaicin) C18H27NO3
Molecular Formula (Dihydrocapsaicin) C18H29NO3
Molecular Weight (Capsaicin) 305.41 g/mol
Molecular Weight (Dihydrocapsaicin) 307.43 g/mol

SECTION 1: CHEMICAL IDENTITY AND DESCRIPTION

Parameter Information
Chemical Name Capsicum Oleoresin (Oleoresin Capsicum)
INCI Name Capsicum Frutescens Extract / Capsicum Annuum Extract
Synonyms Oleoresin Capsicum, Capsicum Extract, Capsaicin Oleoresin, Dihydrocapsaicin, Paprika Oleoresin, Cayenne Extract, Chili Extract, Red Pepper Extract, Capsicum Resin
Abbreviations OC (Oleoresin Capsicum)
CAS Number 8023-77-6
Food Additive Code E165C
Chemical Class Natural oleoresin (phenolic compounds; capsaicinoid family)
Main Active Components Capsaicin (C18H27NO3), Dihydrocapsaicin (C18H29NO3), Nordihydrocapsaicin, Homocapsaicin, Homodihydrocapsaicin
Botanical Source Capsicum frutescens L., Capsicum annuum L. (Solanaceae family)
Physical State (20°C) Clear red, dark red, or brown viscous liquid
Odor / Aroma Very strong, characteristic; detectable at extremely low concentrations (1 part in 11 million)
Taste Extremely pungent/hot (depending on capsaicinoid content)

SECTION 2: PHYSICAL AND CHEMICAL PROPERTIES

Property Value Test Method
Appearance Clear red, dark red, or brown viscous liquid Visual
Odor / Aroma Very strong, characteristic Olfactometric
Taste Extremely pungent/hot Sensory
Density (25°C) 0.92 – 0.95 g/cm3 ASTM D4052
Viscosity (25°C) Highly viscous (depends on capsaicinoid concentration) ASTM D445
Solubility in Water Partially dispersible/emulsifiable General Method
Solubility in Oil Soluble General Method
Solubility in Ethanol Soluble General Method
Solubility in Organic Solvents Soluble in acetone, ether, chloroform General Method
Melting Point Not applicable (viscous liquid) -
Boiling Point Not applicable -
Flash Point >100°C (typical) ASTM D93
Refractive Index (nD20) 1.470 – 1.510 Refractometry
Chemical Character Phenolic compound; lipophilic character  

SECTION 3: CHEMICAL PROPERTIES AND REACTIVITY

Parameter Information
Chemical Class Natural oleoresin; capsaicinoid family (phenolic amides)
Main Components Capsaicin (~69%), Dihydrocapsaicin (~22%), Nordihydrocapsaicin (~7%), Homocapsaicin (~1%), Homodihydrocapsaicin (~1%)
Stability Stable under normal conditions; may degrade upon exposure to heat, light, and oxygen
Decomposition Products (Heating) CO, CO2, NOx, irritating fumes
Incompatible Materials Strong oxidizing agents, strong bases
Light Sensitivity UV light exposure may cause color fading and reduced potency
Heat Sensitivity Capsaicinoids decompose at high temperatures (>200°C)
Hazardous Polymerization Does not occur

SECTION 4: PRODUCTION METHOD

Parameter Description
Botanical Source Ripe fruits of Capsicum frutescens L. and/or Capsicum annuum L.
Extraction Method Solvent extraction (ethyl alcohol or other organic solvents)
Process Drying of ripe fruits, grinding, extraction with solvent, removal of solvent under vacuum
Final Product Viscous, dark red-brown oleoresin
Composition Over 100 identified compounds; capsaicinoids constitute the main active group
Standardization Standardized according to Scoville Heat Units (SHU) or % capsaicin content

SECTION 5: CAPSICUM OLEORESIN STANDARDIZATION

Parameter Low Pungency Medium Pungency High Pungency Very High Pungency
Scoville Heat Units (SHU) 10,000 – 100,000 100,000 – 500,000 500,000 – 1,000,000 1,000,000 – 2,000,000+
Capsaicin Content (%) 0.1 – 1.0% 1.0 – 5.0% 5.0 – 10.0% >10.0%
Typical Use Food flavoring, spice Food, cosmetics Pharmaceutical, topical analgesic Defense (pepper spray)
Color Light red-orange Dark red Dark red-brown Dark brown

SECTION 6: CAPSICUM PRODUCTS COMPARISON

Property Capsicum Oleoresin Capsaicin (Pure) Paprika Oleoresin Red Pepper Powder
Form Viscous liquid Crystalline solid Viscous liquid Powder
Active Component Capsaicinoid mixture Pure capsaicin Carotenoids + low capsaicin Capsaicinoids + fiber
Pungency (SHU) Variable (10K-2M+) 15,000,000 – 16,000,000 Very low (<500) Variable (1K-100K)
Color Dark red-brown White crystalline Deep red Red-orange
Primary Use Food, pharma, defense Pharmaceutical, research Food colorant Food spice
Solubility in Water Low (oil-soluble) Very low Low Partial
Standardization SHU or % capsaicin 99%+ purity ASTA color value SHU

SECTION 7: FUNCTIONAL PROPERTIES AND MECHANISM OF ACTION

Property Description
Flavor and Taste Agent Imparts pungent taste and characteristic pepper aroma to foods; effective even at very low concentrations (ppm level)
Topical Analgesic Capsaicin activates TRPV1 (Transient Receptor Potential Vanilloid 1) receptors; initial burning sensation followed by prolonged analgesic effect
Anti-inflammatory Reduces neurogenic inflammation; inhibits Substance P release from nerve endings
Rubefacient Increases local blood circulation when applied to skin; creates warming sensation
Irritant (Defense) Causes severe irritation of mucous membranes; active component of pepper spray
Antioxidant Free radical scavenging effect due to phenolic structure
Antimicrobial Shows inhibitory effect against certain bacteria and fungi
Metabolism Booster May increase metabolic rate through thermogenic effect

SECTION 8: PRIMARY APPLICATION AREAS

Sector Application Typical Usage / Dosage
Food - Spice Pungent flavoring agent; restaurants and food production 0.01 – 0.5 g/kg
Food - Hot Sauces Hot sauce, ketchup, marinade sauces 0.05 – 1.0%
Pharmaceutical - Topical Analgesic Muscle pain, arthritis, neuropathic pain creams 0.025 – 0.1% capsaicin
Pharmaceutical - Anti-inflammatory Inflammatory skin conditions 0.025 – 0.075%
Defense Industry Pepper spray (OC spray) formulations 5 – 15% oleoresin
Cosmetic Warming creams, anti-cellulite products 0.01 – 0.1%
Animal Repellent Garden and agricultural area animal deterrent 0.1 – 1.0%
Research Capsaicinoid analysis, pharmacological studies Variable

SECTION 9: QUALITY SPECIFICATIONS (FOOD GRADE)

Parameter Specification Test Method
Appearance Clear red-brown viscous liquid Visual
Odor / Aroma Characteristic, strong pepper aroma Olfactometric / Sensory
Total Capsaicinoid Content Per customer specification (0.1 – 10+%) HPLC
Scoville Heat Units (SHU) Per customer specification Calculated (from HPLC)
Density (25°C) 0.92 – 0.95 g/cm3 ASTM D4052
Refractive Index (nD20) 1.470 – 1.510 Refractometry
Acid Value (mg KOH/g) ≤ 10.0 Titrimetric
Peroxide Value (meq/kg) ≤ 20.0 Titrimetric
Residual Solvent (Ethyl Alcohol) ≤ 50 ppm (food grade) HS-GC
Heavy Metals (as Pb) ≤ 10 ppm ICP-MS
Lead (Pb) ≤ 3 ppm ICP-MS
Arsenic (As) ≤ 3 ppm ICP-MS
Mercury (Hg) ≤ 1 ppm ICP-MS
Cadmium (Cd) ≤ 1 ppm ICP-MS
Total Microbial Count ≤ 10,000 CFU/g ISO 4833
Yeast and Mold ≤ 100 CFU/g ISO 21527
Salmonella spp. Negative in 25g ISO 6579
E. coli Negative in 10g ISO 16649

SECTION 10: TOXICOLOGICAL PROFILE

Parameter Value
Acute Oral Toxicity (LD50, Rat) ~160 mg/kg (pure capsaicin); variable for oleoresin
Acute Dermal Toxicity (LD50, Rabbit) > 2,000 mg/kg (oleoresin)
Skin Irritation Severe irritant; burning sensation, redness
Eye Irritation Very severe irritant; may cause temporary blindness
Respiratory Irritation Inhalation of vapor/spray causes severe coughing and breathing difficulty
Skin Sensitization Not sensitizing
Carcinogenicity Not classified (IARC); some studies show conflicting results for capsaicin
Mutagenicity Conflicting results in in vitro tests
Chronic Toxicity Gastrointestinal discomfort at high doses
GRAS Status Recognized as GRAS by FDA as food flavoring

SECTION 11: GHS CLASSIFICATION AND LABELING

GHS Classification (compliant with 1272/2008/EC):

Hazard Class Category H-Statement
Skin Irritation Category 2 H315
Serious Eye Damage/Irritation Category 1 H318
Specific Target Organ Toxicity (STOT - SE) Category 3 H335

Signal Word: DANGER

Hazard Pictograms: GHS05 (Corrosive), GHS07 (Exclamation Mark)

Hazard Statements (H-Codes):

Code Statement
H315 Causes skin irritation
H318 Causes serious eye damage
H335 May cause respiratory irritation

Precautionary Statements (P-Codes):

Code Statement
P261 Avoid breathing vapor/spray
P280 Wear protective gloves/protective clothing/eye protection/face protection
P302+P352 IF ON SKIN: Wash with plenty of water and soap
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P310 Immediately call a POISON CENTER/doctor

SECTION 12: FIRST AID MEASURES

Exposure Route Action to Take
Inhalation Move to fresh air. Seek medical attention if breathing difficulty persists.
Skin Contact Wash with plenty of water and soap for at least 15 minutes. Wipe with vegetable oil or polyethylene glycol. Water alone may be insufficient. Seek medical attention if irritation persists.
Eye Contact Rinse immediately with plenty of water for at least 15-20 minutes. Remove contact lenses if present. Seek immediate medical attention.
Ingestion Rinse mouth with water. Do NOT induce vomiting. Give milk or yogurt. Seek immediate medical attention.

Important Note: Capsaicin is not soluble in water; vegetable oil, polyethylene glycol (PEG-400), or 50% ethanol solution is more effective for removal from skin.

SECTION 13: FIREFIGHTING MEASURES

Parameter Information
Fire Hazard Combustible liquid (high viscosity oil)
Flash Point >100°C (typical)
Hazards During Fire Releases CO, CO2, NOx, irritating fumes when heated or burned
Suitable Extinguishing Media CO2, dry chemical powder, alcohol-resistant foam, water mist
Special Protective Equipment Self-contained breathing apparatus (SCBA), full chemical protective clothing

SECTION 14: STORAGE AND SHELF LIFE

Parameter Information
Storage Conditions Cool (15-25°C), dry, well-ventilated area; light-protective packaging
Container Requirements Tightly closed, airtight containers (to prevent oxidation)
Keep Away From Heat, direct sunlight (UV), oxygen, strong oxidizing agents
Shelf Life 24 months (unopened original packaging under appropriate storage conditions)
Stability Note Color fading and potency loss may occur upon exposure to light, heat, and oxygen; storage under inert atmosphere (N2) recommended

SECTION 15: PACKAGING OPTIONS

Packaging Type Quantity Material
Aluminum bottle (light-protective) 1 kg Aluminum
Aluminum bottle (light-protective) 5 kg Aluminum
HDPE drum (light-protected) 25 kg HDPE
HDPE drum (light-protected) 50 kg HDPE
Stainless steel container 200 kg Stainless steel 316L

SECTION 16: TRANSPORTATION INFORMATION

Parameter Information
UN Number Not regulated (for food grade; evaluate for high concentrations)
Hazard Class Not applicable (food grade)
Packing Group Not applicable
ADR/RID Not regulated (food grade)
IMDG Code Not regulated (food grade)
IATA (Air) Not regulated (food grade)
Marine Pollutant No
Transport Temperature Ambient (15-25°C); protect from freezing and excessive heat

SECTION 17: REGULATORY STATUS

Region / Authority Status
European Union Approved as food flavoring (EC 1334/2008); Code E165C
USA (FDA) GRAS; approved as food flavoring and topical analgesic
JECFA (FAO/WHO) Evaluated as food flavoring
Turkey Approved under Turkish Food Codex Regulation on Flavorings
Cosmetics Regulation (EC 1223/2009) Listed in INCI; use at limited concentrations
Defense Industry Specific regulations for pepper spray formulations in certain countries
Halal Available
Kosher Available

SECTION 18: OTHER NAMES AND SYNONYMS

Type Name
English Names Oleoresin Capsicum, Capsicum Extract, Capsaicin Oleoresin, Dihydrocapsaicin, Paprika Oleoresin, Cayenne Extract, Chili Extract, Capsicum Oleoresin, Red Pepper Extract
Other Language Names Kapsikum Ekstraktı, Capsicum Extrakt (various languages)
INCI Name Capsicum Frutescens Extract / Capsicum Annuum Extract
Abbreviations OC (Oleoresin Capsicum)
Food Additive Code E165C
CAS Number 8023-77-6

SECTION 19: SECTORAL NAMING TABLE

Sector Preferred Name
Food (General) Paprika Oleoresin, Red Pepper Extract, Chili Extract
Food (Pungent Flavor) Capsicum Oleoresin, Capsicum Extract
Pharmaceutical Capsaicin Oleoresin, Dihydrocapsaicin
Defense Industry Oleoresin Capsicum (OC)
Cosmetic Capsicum Frutescens Extract, Capsicum Annuum Extract (INCI)
ERP / Supply Chain CAS 8023-77-6, E165C

SECTION 20: SUMMARY TABLE

Parameter Value
Product Capsicum Oleoresin (Oleoresin Capsicum)
CAS Number 8023-77-6
Food Additive Code E165C
Molecular Weight (Capsaicin) 305.41 g/mol
Appearance Dark red-brown viscous liquid
Density (25°C) 0.92 – 0.95 g/cm3
Primary Function Flavoring agent, topical analgesic, irritant
Shelf Life 24 months
GHS Signal Word Danger

SECTION 21: CRITICAL WARNINGS AND BEST PRACTICES

CRITICAL SAFETY WARNINGS:

  1. Serious Eye Damage: Eye contact may cause serious damage and temporary blindness. Wear protective goggles/face shield.

  2. Skin Irritation: Causes severe burning sensation on skin. Wear protective gloves and clothing.

  3. Respiratory Irritation: Inhalation of vapor or spray causes severe coughing and breathing difficulty. Ensure good ventilation.

  4. Water Ineffective: Capsaicin is not soluble in water; use vegetable oil, polyethylene glycol, or 50% ethanol for removal from skin. Water alone is ineffective.

  5. Cross-Contamination: Detectable at extremely low concentrations; thoroughly clean equipment and surfaces.

BEST PRACTICE RECOMMENDATIONS:

  1. Skin Contact Response: Wipe affected area with vegetable oil or polyethylene glycol (PEG-400), then wash with soap and water.

  2. Light Protection: Store in amber-colored containers to protect from UV light.

  3. Inert Atmosphere: Store under nitrogen (N2) for long-term preservation.

  4. Standardization: When purchasing, request product standardized according to Scoville Heat Units (SHU) or % capsaicin content.

  5. Pre-Testing: Conduct small-scale testing before use in food formulations; pungency levels may vary between batches.

LEGAL DISCLAIMER:

The information provided in this document is presented in good faith based on our current knowledge and experience; however, since all usage conditions are beyond our control, it does not constitute a binding specification or warranty. This Technical Data Sheet is for informational purposes only. Users are obligated to test the suitability for their own applications. For complete safety, storage, handling, transportation, disposal, and regulatory compliance information, refer to the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier.

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