Glutamine, L Glutamine, levoglutamide, 56-85-9 

L-Glutamine, Glutamine, 56-85-9

Chemical Identity

• Chemical Name: L-Glutamine

• Molecular Formula: C₅H₁₀N₂O₃

• Molecular Weight: 146.15 g/mol

• CAS Number: 56-85-9

• Appearance: White crystalline powder

• Solubility: Soluble in water, forms near-neutral solutions; slightly soluble in ethanol

• Stability: Hygroscopic; store in a cool, dry place. Shelf life ~2 years

Biological Functions

• Most abundant free amino acid in human blood and muscle tissue

• Muscle metabolism: ~70% of body glutamine is produced and stored in skeletal muscle

• Gut health: Primary energy source for intestinal epithelial cells; supports mucosal integrity

• Immune system: Fuels lymphocytes and macrophages; critical during illness, stress, or trauma

• Detoxification: Transports nitrogen between tissues; helps remove excess ammonia

• Cell growth and repair: Essential for tissue regeneration and wound healing

Applications

Pharmaceutical / Medical

• Immune support: Enhances immune function during illness, surgery, or chemotherapy

• Gut health: Used in conditions like Crohn’s disease, IBS, or mucosal damage

• Oncology: Protects intestinal lining during chemotherapy or radiation therapy

• Critical care: Supplemented in parenteral nutrition for trauma or burn patients

Sports Nutrition

• Muscle recovery: Reduces muscle breakdown after intense exercise

• Endurance: Helps preserve glycogen stores during prolonged training

• Supplement form: Typically consumed as powder, 5–10 g/day

Food / Nutraceuticals

• Added to functional foods, protein bars, and sports drinks

• Used in immune-support formulations

Veterinary

• Incorporated into specialized animal feed for gut and immune health

Research / Biotechnology

• Cell culture medium additive (essential for cell proliferation)

• Studied in nitrogen metabolism and stress response pathways

Risks and Considerations

• Side effects: High doses may cause mild gastrointestinal discomfort or kidney strain

• Safety: Generally safe for healthy individuals; caution in renal disease

• Dosage: 5–10 g/day in sports nutrition; higher doses in clinical settings under medical supervision

Commercial Formats

• Pharma grade: 25 kg fiber drum or HDPE bag, GMP/ISO certified

• Supplement grade: 300–500 g jars, capsules, tablets

• Documentation: COA, TDS, GMP certificates required for compliance