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Send EmailPovidone Iodine, PVP Iodine, Polyvinyl Pyrrolidone-iodine, Pharmadine, Betadine, PVP-I, 25655-41-8, 74500-22-4
Povidone Iodine (CAS 25655-41-8 & 74500-22-4) versus Elemental Iodine (CAS 7553-56-2 & 12190-71-5)—optimized for bilingual documentation, ERP integration, and audit-ready summaries:
🧪 Comparative Table: Povidone Iodine vs. Elemental Iodine
| Feature | Povidone Iodine (CAS 25655-41-8 / 74500-22-4) | Elemental Iodine (CAS 7553-56-2 / 12190-71-5) |
|---|---|---|
| 🔬 Chemical Structure | Iodophor complex (Polyvinylpyrrolidone + Iodine) | Pure diatomic iodine (I₂) |
| ⚖️ Molecular Weight | ~365–493 g/mol (depends on complex ratio) | 253.81 g/mol |
| 🧪 Iodine Content | ~9–14% (controlled release) | 100% iodine |
| ☠️ Toxicity | Low – safe for skin and mucosa | High – irritant and volatile |
| 💧 Solubility | Soluble in water, ethanol, methanol, isopropanol | Slightly soluble in water; soluble in organic solvents |
| 🧴 Physical Form | Yellowish-brown amorphous powder or gel | Dark violet crystals or prilled granules |
| 🧼 Application Type | Topical antiseptic, wound care, surgical prep | Chemical synthesis, analytical reagent, iodized salt, feed additive |
| 💊 Pharmaceutical Use | Direct skin/mucosa application | API intermediate or tincture component |
| 🔬 Laboratory Use | Microbiological disinfectant, in vitro rinsing | Redox titration, iodine value determination |
| 📦 Storage Stability | Stable under dry, sealed conditions | Sensitive to oxidation and sublimation |
| 📋 CAS Variants | 25655-41-8 (standard PVP-I), 74500-22-4 (high-iodine variant) | 7553-56-2 (prilled form), 12190-71-5 (high-purity analytical grade) |
🏭 Sectoral Usage Comparison
| Sector | Povidone Iodine Applications | Elemental Iodine Applications |
|---|---|---|
| Pharmaceutical | Antiseptic gels, surgical prep, gynecological rinses | API synthesis, tincture iodine |
| Hygiene & Disinfection | Skin cleansers, wound disinfectants | Raw material for iodophor production |
| Laboratory & Clinical | In vitro rinsing, microbiological testing | Analytical reagent, iodine value testing |
| Cosmetics | Active ingredient in skin hygiene products | Not typically used directly |
| Medical Equipment | Disinfection of surgical tools and metal surfaces | Used in sterilization formulations |
| Agriculture & Feed | Not direct; used via iodophor formulations | Micronutrient additive in animal feed |
| Food Industry | Not direct; used in antiseptic packaging | Iodized salt production |
| Chemical Industry | Iodophor synthesis | Halogenation, catalyst, intermediate |
| Trade & Customs | CAS 25655-41-8 / 74500-22-4 for antiseptic products | CAS 7553-56-2 / 12190-71-5 for technical iodine classification |
🧾 Summary of CAS Numbers
| CAS Number | Compound Type | Notes |
|---|---|---|
| 25655-41-8 | Povidone Iodine (standard) | Most common iodophor antiseptic; USP/EP compliant |
| 74500-22-4 | Povidone Iodine (variant) | Higher iodine content; used in gels and surgical formulations |
| 7553-56-2 | Elemental Iodine (prilled) | Pure iodine; used in synthesis, analysis, and iodized salt |
| 12190-71-5 | Elemental Iodine (pure) | High-purity analytical grade; used in lab and pharma synthesis |
Here’s a comprehensive list of alternative names and synonyms for both Povidone Iodine and Elemental Iodine, organized by CAS number and usage context:
🧾 Synonyms by CAS Number
🔬 Povidone Iodine (CAS 25655-41-8 / 74500-22-4)
These refer to iodophor complexes used in antiseptic formulations:
| 🧪 Synonym / Trade Name | 📌 Context / Notes |
|---|---|
| Povidone Iodine | INCI name, most common international designation |
| PVP-I | Abbreviation for Polyvinylpyrrolidone-Iodine |
| Povidon İyot | Turkish spelling |
| Povidon İyodin | Alternate Turkish spelling |
| Polivinilprolidon İyot | Turkish chemical variant |
| Provodin | Trade name |
| Betadine | Widely known commercial brand |
| Efo-dine | Regional trade name |
| Pharmadine | Brand name used in hospital-grade antiseptics |
| PVP Iodine | Common catalog name |
| Polyvinylpyrrolidone-iodine complex | Structural description |
| Hydrogen triiodide compound | Used in CAS 74500-22-4 descriptions |
🔬 Elemental Iodine (CAS 7553-56-2 / 12190-71-5)
These refer to pure iodine used in synthesis, analysis, and iodized products:
| 🧪 Synonym / Trade Name | 📌 Context / Notes |
|---|---|
| Iodine | General name |
| Molecular Iodine | Structural reference (I₂) |
| Diiodine | Formal chemical name |
| Prilled Iodine | Granular form used in industry |
| Iodine Crystals | Describes physical appearance |
| Iodine Powder | Commercial form |
| Iodine (USP/ACS) | Pharmaceutical and analytical grade |
| Iodine Solution Standard Substance | Analytical reagent grade |
| Iodien | German variant spelling |
| HX968 | Supplier-specific catalog code |
| Iodide (I21-) | Registry variant (not to be confused with iodide ion) |
CAS: 25655-41-8;74500-22-4
Molecular Formula: C6H10I3NO
Names and Identifiers
| Name | Povidone Iodine |
| Synonyms | PVP-I Betadine Efo-dine Povidone Iodine PVP-IPVP-Iodine Povidone-iodine compd. with iodine 1-ethenyl-homopolymer Polyvinylpyrrolidone-iodine complex Hydrogen triiodide, compd. with 1-ethenyl-2-pyrrolidinone homopolymer |
| CAS | 25655-41-8 74500-22-4 |
| InChI | InChI=1/C6H9NO.I2/c1-2-7-5-3-4-6(7)8;1-2/h2H,1,3-5H2 |
Physico-chemical Properties
| Molecular Formula | C6H10I3NO |
| Molar Mass | 492.87 |
| Melting Point | 300℃ |
| Boling Point | 217.6°C at 760 mmHg |
| Flash Point | 93.9°C |
| Vapor Presure | 0.132mmHg at 25°C |
| Appearance | Brown powder |
| Storage Condition | Room Temprature |
| MDL | MFCD00084483 |
| Physical and Chemical Properties | Properties this product is a yellow-brown to red-brown amorphous powder. |
| Use | It has the germicidal effect of iodine, and is used as a germicidal disinfectant, a bacteriostatic agent, an antiseptic for eye drops, nasal drops, cream, etc., and can also be made into a disinfectant. |
Risk and Safety
| Safety Description | S24/25 - Avoid contact with skin and eyes. |
Reference
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Reference Show more |
1. [IF=5.833] Wei Shengnan et al."Paper chip-based colorimetric assay for detection of Salmonella typhimurium by combin... |
Introduction
Slightly smelly, the aqueous solution is acidic. Soluble in water and ethanol. Insoluble in ether, chloroform, acetone, ethane and carbon tetrachloride. The aqueous solution of this product has no shortcomings of iodine tincture, light color, easy to elute, low irritation to mucous membranes, no need to use ethanol to deiodinate, no corrosion, and low toxicity.
CAS NR: 74500-22-4 Povidone Iodine
CAS: 25655-41-8;74500-22-4
Molecular Formula: C6H10I3NO
Names and Identifiers
| Name | Povidone Iodine |
| Synonyms | PVP-I Betadine Efo-dine Povidone Iodine PVP-IPVP-Iodine Povidone-iodine compd. with iodine 1-ethenyl-homopolymer Polyvinylpyrrolidone-iodine complex Hydrogen triiodide, compd. with 1-ethenyl-2-pyrrolidinone homopolymer |
| CAS | 25655-41-8 74500-22-4 |
| InChI | InChI=1/C6H9NO.I2/c1-2-7-5-3-4-6(7)8;1-2/h2H,1,3-5H2 |
Physico-chemical Properties
| Molecular Formula | C6H10I3NO |
| Molar Mass | 492.87 |
| Melting Point | 300℃ |
| Boling Point | 217.6°C at 760 mmHg |
| Flash Point | 93.9°C |
| Vapor Presure | 0.132mmHg at 25°C |
| Appearance | Brown powder |
| Storage Condition | Room Temprature |
| MDL | MFCD00084483 |
| Physical and Chemical Properties | Properties this product is a yellow-brown to red-brown amorphous powder. |
| Use | It has the germicidal effect of iodine, and is used as a germicidal disinfectant, a bacteriostatic agent, an antiseptic for eye drops, nasal drops, cream, etc., and can also be made into a disinfectant. |
Risk and Safety
| Safety Description | S24/25 - Avoid contact with skin and eyes. |
Introduction
Slightly smelly, the aqueous solution is acidic. Soluble in water and ethanol. Insoluble in ether, chloroform, acetone, ethane and carbon tetrachloride. The aqueous solution of this product has no shortcomings of iodine tincture, light color, easy to elute, low irritation to mucous membranes, no need to use ethanol to deiodinate, no corrosion, and low toxicity.
