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Dipropylene Glycol Dibenzoate, Oxydipropyl Dibenzoate, DPGDB, 27138-31-4

Dipropylene Glycol Dibenzoate, Oxydipropyl Dibenzoate, DPGDB, 27138-31-4

DIPROPYLENE GLYCOL DIBENZOATE (DPGDB)

CAS 27138-31-4 | C₂₀H₂₂O₅

SECTION 1: PRODUCT IDENTITY AND DEFINITION

Parameter Description
Product Name Dipropylene Glycol Dibenzoate
IUPAC Name 2-(2-benzoyloxypropoxy)propyl benzoate
Other Names Oxydipropyl dibenzoate, 1,1'-Oxybis-2-propanol dibenzoate, 1,1'-Dimethyl-2,2'-oxydiethyl dibenzoate, 1,1'-Oxybis(propan-2,1-diyl) dibenzoate, Di(1,2-propylene glycol) dibenzoate, Dipropylene Glycol Dibenzoate (DPGDB)
Chemical Formula C₂₀H₂₂O₅
Molecular Weight 326.39 g/mol
CAS Number 27138-31-4
EC Number 202-296-9
UNII 9QQI0RSO3H
Chemical Class Benzoate Ester / Plasticizer
REACH Status Registered and compliant
TSCA (USA) Listed

Description: Dipropylene Glycol Dibenzoate (DPGDB) is a high-solvating benzoate plasticizer with dipropylene glycol dibenzoate as its primary component. It is proposed as an environmentally friendly alternative to o-benzene plasticizers (phthalates) and is widely used in various applications. It is a clear, colorless liquid with excellent solvency power and compatibility with a wide range of polar polymers.

SECTION 2: SYNONYMS AND OTHER NAMES

No Synonym / Other Name
1 Dipropylene Glycol Dibenzoate
2 DPGDB
3 Oxydipropyl Dibenzoate
4 1,1'-Oxybis-2-propanol Dibenzoate
5 1,1'-Dimethyl-2,2'-oxydiethyl Dibenzoate
6 1,1'-Oxybis(propan-2,1-diyl) Dibenzoate
7 Di(1,2-Propylene Glycol) Dibenzoate
8 2-(2-benzoyloxypropoxy)propyl benzoate
9 1-(2-benzoyloxy-propoxy)propan-2-yl benzoate
10 1,1'-Oxybis(2-propanol) Dibenzoate
11 2-Propanol, 1,1'-oxybis-, dibenzoate
12 Oxybis(propan-1,2-diyl) Dibenzoate
13 1,1'-Oxydi-2-propanol Dibenzoate
14 Dipropylene Glycol Dibenzoate (General)
15 27138-31-4
16 EINECS 202-296-9
17 94-03-1 (related)
18 DTXSID6027921
19 SCHEMBL1255193
20 CHEMBL1877406

SECTION 3: CHEMICAL STRUCTURE AND MOLECULAR PROPERTIES

Parameter Description
Chemical Family Benzoate Esters / Diester Plasticizers
Structure Dipropylene glycol ether chain with two benzoate ester groups at both ends
Functional Groups Two Ester Groups (-COO-), Ether Group (-O-), Two Aromatic Rings (Phenyl)
Molecular Structure C₆H₅-COO-CH(CH₃)-CH₂-O-CH₂-CH(CH₃)-OOC-C₆H₅
SMILES Notation CC(COCC(C)OC(=O)C1=CC=CC=C1)OC(=O)C2=CC=CC=C2
InChI InChI=1S/C20H22O5/c1-15(23-19(21)17-9-5-3-6-10-17)13-25-14-16(2)24-20(22)18-11-7-4-8-12-18/h3-12,15-16H,13-14H2,1-2H3
InChI Key -
Log P (Hydrophobicity) ~4.2 – 4.5 (moderately lipophilic)
HLB (Hydrophilic-Lipophilic Balance) ~4-5 (lipophilic)
Dielectric Constant ~6-7 (moderate polarity)
Solubility Parameter ~9.5 – 10.0 (cal/cm³)^0.5

Structural Formula:

text

C₆H₅ - COO - CH₂ - CH - O - CH₂ - CH - OOC - C₆H₅
              |              |
             CH₃            CH₃

     Dipropylene Glycol Dibenzoate (DPGDB)

Description: Dipropylene Glycol Dibenzoate consists of a dipropylene glycol ether chain with two benzoate ester groups attached at both ends. The molecule contains two phenyl rings, two ester groups, and an ether group. This structure provides high polarity, excellent solvency power, and compatibility with a wide range of polar polymers. The benzoate groups contribute to the plasticizing effect, while the ether linkage provides flexibility. The high molecular weight (326.39 g/mol) ensures low volatility and good permanence in polymer matrices.

SECTION 4: PHYSICAL APPEARANCE AND FORM

Parameter Specification Typical Value Test Method
Physical State Liquid - Visual
Color Clear, Colorless to Slightly Yellow - Visual
Color (APHA) ≤ 80 < 50 ASTM D1209
Odor Mild, characteristic - Organoleptic
Clarity Clear, free from turbidity - Visual
Purity (GC) ≥ 99.0% 99.0 – 99.5% GC
Acid Content ≤ 0.1% (as benzoic acid) < 0.05% Titration
Water Content ≤ 0.1% < 0.05% Karl Fischer

Description: Dipropylene Glycol Dibenzoate is a clear, colorless to slightly yellow liquid with a mild characteristic odor. It is a free-flowing liquid with high purity (≥99.0%). Low acid content and low water content indicate high product quality and stability. The APHA color (≤80) confirms the product's clarity and purity.

SECTION 5: PHYSICAL AND CHEMICAL PROPERTIES

Parameter Specification Typical Value Test Method
Physical State Liquid - Visual
Color (APHA) ≤ 80 < 50 ASTM D1209
Density (25°C) ~1.144 g/cm³ 1.143 – 1.145 g/cm³ ASTM D4052
Density (20°C) ~1.146 g/cm³ - ASTM D4052
Boiling Point 464.2 °C ~464 °C ASTM D86
Melting/Freezing Point ~ -40 °C to -30 °C ~ -35 °C DSC
Flash Point > 200 °C > 210 °C ASTM D93
Vapor Pressure (25°C) 0 mmHg (negligible) < 0.01 mmHg -
Viscosity (25°C) ~100 – 150 cP ~120 cP Brookfield
Refractive Index (n²⁰/D) ~1.525 – 1.530 ~1.528 ASTM D1218
Surface Tension ~35 – 40 mN/m ~38 mN/m -
Specific Gravity (25°C/25°C) ~1.144 ~1.144 ASTM D4052
Solubility in Water Slightly soluble (~0.1 g/L) < 0.1 g/L -
Saponification Value ~340 – 350 mg KOH/g ~344 mg KOH/g Titration
Acid Value ≤ 0.5 mg KOH/g < 0.2 Titration
Hydroxyl Value ≤ 5.0 mg KOH/g < 2.0 Titration

Description: Dipropylene Glycol Dibenzoate is a liquid with a density of approximately 1.144 g/cm³ at 25°C. It has a high boiling point (464°C) and very low vapor pressure, indicating low volatility and good permanence. The viscosity at 25°C is approximately 120 cP, providing good processability. The refractive index is approximately 1.528. The flash point is above 210°C, indicating low flammability. The saponification value confirms the ester content, and low acid and hydroxyl values indicate high purity.

SECTION 6: SOLUBILITY AND MISCIBILITY

Solvent / Medium Solubility / Miscibility (25°C)
Water Slightly soluble (< 0.1 g/L)
Ethanol (Absolute) Miscible
Methanol Miscible
Acetone Miscible
Ethyl Acetate Miscible
Toluene Miscible
Xylene Miscible
Mineral Oil Miscible
Vegetable Oils Miscible
Plasticizers (Phthalates) Miscible
PVC Highly compatible
Polystyrene Highly compatible
Acrylic Resins Highly compatible
Polyurethanes Highly compatible

Description: Dipropylene Glycol Dibenzoate is miscible with most organic solvents including ethanol, methanol, acetone, ethyl acetate, toluene, xylene, and mineral oils. It is slightly soluble in water. It shows excellent compatibility with a wide range of polar polymers including PVC, polystyrene, acrylic resins, and polyurethanes. This broad compatibility is one of its key advantages as a plasticizer.

SECTION 7: PURITY AND ANALYTICAL SPECIFICATIONS

Parameter Specification Typical Value Test Method
Purity (GC) ≥ 99.0% 99.0 – 99.5% GC (FID)
Acid Content (as benzoic acid) ≤ 0.1% < 0.05% Titration
Water Content (Karl Fischer) ≤ 0.1% < 0.05% Karl Fischer
Color (APHA) ≤ 80 < 50 ASTM D1209
Appearance Clear, Colorless - Visual
Density (25°C) 1.140 – 1.148 g/cm³ 1.144 g/cm³ ASTM D4052
Refractive Index (n²⁰/D) 1.525 – 1.530 1.528 ASTM D1218
Acid Value ≤ 0.5 mg KOH/g < 0.2 Titration
Saponification Value 340 – 350 mg KOH/g 344 mg KOH/g Titration
Hydroxyl Value ≤ 5.0 mg KOH/g < 2.0 Titration
Ash Content ≤ 0.1% < 0.05% USP <281>
Heavy Metals (Pb) ≤ 10 ppm < 5 ppm USP <231>
Specific Gravity (25°C/25°C) 1.140 – 1.148 1.144 ASTM D4052

Description: Dipropylene Glycol Dibenzoate is supplied in high purity (≥99.0%). The purity is determined by gas chromatography (GC). Low acid and water content indicate high quality and stability. The saponification value (340-350 mg KOH/g) confirms the ester content. Low hydroxyl value indicates minimal monoester or residual alcohol content. Heavy metal content is controlled to ensure product safety.

SECTION 8: SPECTROSCOPIC PROPERTIES

Parameter Value / Description
UV-Vis Maximum Absorbance (λmax) ~230 nm, ~270 nm (ethanol)
IR (ATR) Characteristic Bands 3060-3080 cm⁻¹ (C-H aromatic), 2950-2980 cm⁻¹ (C-H aliphatic), 1710-1730 cm⁻¹ (C=O ester, strong), 1600-1580 cm⁻¹ (C=C aromatic), 1450-1460 cm⁻¹ (C-H bending), 1270-1280 cm⁻¹ (C-O-C ester), 1100-1120 cm⁻¹ (C-O-C ether), 700-710 cm⁻¹ (monosubstituted benzene)
¹H-NMR (CDCl₃) δ 8.0 (m, 4H, ortho Ar-H), 7.5 (m, 2H, para Ar-H), 7.4 (m, 4H, meta Ar-H), 5.3 (m, 2H, CH), 3.6-3.8 (m, 4H, CH₂), 1.3 (d, 6H, CH₃)
¹³C-NMR (CDCl₃) δ 166.0 (C=O), 133.0 (C aromatic), 130.0 (C aromatic), 129.5 (C aromatic), 128.5 (C aromatic), 72.0 (CH), 68.0 (CH₂), 16.5 (CH₃)
Mass Spectrum (MS - EI) m/z 326 [M⁺], 221, 105 (benzoyl cation), 77 (phenyl cation), 57
GC-MS Retention Index ~2100-2200 (DB-5 column)

Description: These spectroscopic data are used for structural identification and purity control of Dipropylene Glycol Dibenzoate. The IR spectrum shows a strong ester carbonyl absorption at 1710-1730 cm⁻¹ and C-O-C ester bands at 1270-1280 cm⁻¹. The ¹H-NMR spectrum shows characteristic signals for the benzoate aromatic protons, methine protons, methylene protons, and methyl protons. The mass spectrum shows the molecular ion at m/z 326 and the characteristic benzoyl cation at m/z 105.

SECTION 9: THERMAL PROPERTIES AND STABILITY

Parameter Value / Description
Decomposition Onset Temperature ~300 °C (by TGA)
Maximum Decomposition Rate ~350-380 °C (by TGA)
Glass Transition Temperature (Tg) ~ -50 °C to -40 °C
Thermal Stability Stable up to 250°C for processing
pH Stability Stable in pH 4 – 9 range (hydrolysis above pH 10)
Light Stability Stable under normal light conditions; may yellow upon prolonged UV exposure
Hydrolytic Stability Resistant to hydrolysis at room temperature; hydrolysis accelerated by strong acids or bases
Oxidative Stability Stable in air; resistant to oxidation
Storage Stability Stable when stored in sealed containers away from heat and light
Volatility Very low volatility due to high molecular weight

Description: Dipropylene Glycol Dibenzoate is thermally stable up to 250°C, making it suitable for high-temperature processing of polymers and plastics. Decomposition begins above 300°C. It is stable across a wide pH range (pH 4-9) but hydrolysis can occur under strongly acidic or basic conditions at elevated temperatures. It is resistant to oxidation and has very low volatility, ensuring good permanence in polymer matrices. The low glass transition temperature (Tg) contributes to its excellent plasticizing efficiency.

SECTION 10: PLASTICIZING MECHANISM AND FUNCTIONAL PROPERTIES

Property Description / Mechanism
Plasticizer Function Reduces glass transition temperature (Tg), increases flexibility, and improves processability of polymers
Mechanism Intercalates between polymer chains, reducing intermolecular forces and increasing free volume
Compatibility Excellent compatibility with PVC, polyurethanes, acrylics, polystyrene, and other polar polymers
Solvency Power High solvency power for polar and moderately polar polymers and resins
Efficiency High plasticizing efficiency; lower loading required compared to some conventional plasticizers
Permanence Low volatility, good migration resistance, excellent extractability resistance
Flexibility Imparted Provides excellent flexibility even at low temperatures
Viscosity Reduction Significantly reduces viscosity of polymer compounds and plastisols
Durability Excellent resistance to aging, weathering, and UV degradation
Performance Imparts good mechanical properties, tensile strength, and elongation

Description: Dipropylene Glycol Dibenzoate functions as a high-performance plasticizer. Its mechanism involves intercalating between polymer chains, reducing intermolecular forces and increasing free volume, which lowers the glass transition temperature (Tg) and increases polymer flexibility. Its high solvency power and excellent compatibility with a wide range of polar polymers make it a versatile plasticizer. It provides excellent flexibility, even at low temperatures, and has very low volatility, ensuring good permanence. It imparts good mechanical properties including tensile strength and elongation.

SECTION 11: ADHESIVE APPLICATIONS

Application Category Function / Benefit Typical Use Level
Water-Based Adhesives    
White Latex Adhesives Plasticizer, improves flexibility and adhesion 5 – 15%
Wood Adhesives Plasticizer, enhances wetting and penetration 5 – 15%
Plywood Adhesives Plasticizer, improves bonding strength 5 – 10%
Paper Packaging Adhesives Plasticizer, improves flexibility and tack 3 – 10%
Lamination Adhesives Plasticizer, improves adhesion and flexibility 5 – 10%
Smoke Adhesives Plasticizer, enhances performance 3 – 8%
Hot Melt Adhesives    
EVA-Based Hot Melts Plasticizer, reduces viscosity, improves flexibility 5 – 20%
Polyurethane Hot Melts Plasticizer, improves processing and flexibility 5 – 15%
Pressure Sensitive Adhesives (PSA)    
Acrylic PSAs Plasticizer, improves tack and peel strength 5 – 15%
Rubber-Based PSAs Plasticizer, improves adhesion and flexibility 5 – 20%
Construction Adhesives Plasticizer, improves flexibility and weather resistance 5 – 15%

Description: Dipropylene Glycol Dibenzoate is widely used in adhesive formulations due to its excellent solvency, compatibility with polar polymers, and plasticizing efficiency. It improves flexibility, adhesion, wetting, and tack in water-based adhesives (white latex, wood, plywood, paper packaging, lamination adhesives). It also finds application in hot melt adhesives, pressure sensitive adhesives, and construction adhesives. Its low volatility ensures long-term flexibility and adhesion performance.

SECTION 12: POLYMER AND PLASTIC APPLICATIONS

Application Category Function / Benefit Typical Use Level
PVC Products    
Flexible PVC (Toys, Flooring) Primary plasticizer, provides flexibility and durability 20 – 50% (phr)
PVC Gloves Plasticizer, provides softness and flexibility 20 – 40% (phr)
PVC-Plastic Impregnation Products Plasticizer, improves processing and flexibility 15 – 35% (phr)
PVC Water Hoses Plasticizer, provides flexibility and durability 20 – 40% (phr)
Synthetic Leather (PVC) Plasticizer, provides softness and durability 25 – 45% (phr)
PVC Film and Sheeting Plasticizer, provides flexibility and clarity 20 – 40% (phr)
Polyurethane Applications    
Polyurethane Elastomers Plasticizer, improves flexibility and processability 5 – 20%
Polyurethane Rubber Rollers Plasticizer, improves elasticity and durability 5 – 15%
Polyurethane Sealants Plasticizer, improves workability and flexibility 5 – 15%
Other Polymers    
Polystyrene Plasticizer, improves flow and impact resistance 5 – 15%
Acrylic Resins Plasticizer, improves flexibility and processing 5 – 15%
Teslin (Synthetic Paper) Plasticizer, improves flexibility and printability 5 – 15%

Description: Dipropylene Glycol Dibenzoate is an excellent plasticizer for PVC, polyurethanes, and other polar polymers. In PVC applications, it provides flexibility, durability, and good processing characteristics. It is used in flexible PVC products including toys, flooring, gloves, water hoses, synthetic leather, and film. It is also an effective plasticizer for polyurethane elastomers, sealants, and rubber rollers. Its compatibility with polystyrene and acrylic resins expands its application range. It is a non-phthalate alternative for phthalate-sensitive applications.

SECTION 13: COATING, INK AND SEALANT APPLICATIONS

Application Category Function / Benefit Typical Use Level
Coatings    
Industrial Coatings Plasticizer, improves flexibility and adhesion 2 – 10%
Automotive Coatings Plasticizer, improves flexibility and weatherability 2 – 8%
Wood Coatings Plasticizer, improves flexibility and film formation 2 – 8%
Coil Coatings Plasticizer, improves flexibility and adhesion 2 – 8%
Printing Inks    
Flexographic Inks Plasticizer, improves flexibility and adhesion 3 – 10%
Gravure Inks Plasticizer, improves flexibility and printability 3 – 10%
Screen Printing Inks Plasticizer, improves flexibility and adhesion 3 – 8%
Sealants    
Polysulfide Sealants Plasticizer, improves workability and flexibility 5 – 15%
Polyurethane Sealants Plasticizer, improves workability and flexibility 5 – 15%
Silicone Sealants Plasticizer, improves workability 2 – 10%
Mastics and Caulks Plasticizer, improves workability and adhesion 5 – 15%
Latex Mastics Plasticizer, improves flexibility and adhesion 5 – 15%

Description: Dipropylene Glycol Dibenzoate is used in coatings, printing inks, and sealants to improve flexibility, adhesion, and workability. It functions as a film-forming aid and plasticizer in industrial, automotive, and wood coatings. In printing inks (flexographic, gravure, screen printing), it improves flexibility and adhesion to substrates. It is widely used as a plasticizer in polysulfide and polyurethane sealants, mastics, and caulks, providing excellent workability and long-term flexibility.

SECTION 14: INDUSTRIAL AND OTHER APPLICATIONS

Application Function / Description Typical Use Level
Pesticides Solvent and carrier for pesticide formulations 5 – 20%
Fluorescent Materials Solvent and plasticizer for fluorescent pigments 5 – 15%
Dye Carriers Carrier and solvent for dyes 5 – 20%
Filling Compounds Plasticizer and filler in filling materials 5 – 15%
Cable Compounds Plasticizer for cable insulation and sheathing 15 – 35% (phr)
Flooring Compounds Plasticizer for resilient flooring 20 – 40% (phr)
Textile Coatings Plasticizer for textile coating applications 10 – 30%
Air Fresheners Solvent and carrier for fragrances 5 – 20%

Description: Dipropylene Glycol Dibenzoate finds application in a wide range of industrial applications. In pesticide formulations, it functions as a solvent and carrier. It is used as a solvent and plasticizer for fluorescent materials, dyes, and filling compounds. In cable compounds and flooring compounds, it provides flexibility and durability. In textile coatings, it improves hand and flexibility. Its versatility and environmental friendliness make it a preferred choice for many industrial applications.

SECTION 15: COSMETIC AND PERSONAL CARE APPLICATIONS

Application Function / Description Typical Use Level
Moisturizing Products Humectant and moisturizer 1 – 5%
Sunscreen Products Solvent and plasticizer for UV filters 1 – 5%
Anti-aging Creams Moisturizer, improves skin feel 1 – 5%
Skin Care Lotions Emollient, improves skin feel 1 – 5%
Hair Care Products Conditioning agent, improves shine and feel 1 – 5%

Description: Dipropylene Glycol Dibenzoate is also used in the cosmetic industry for its moisturizing, sunscreen, and anti-aging properties. It functions as a humectant and moisturizer in skin care products, improves skin feel and appearance, and serves as a solvent and plasticizer for UV filters in sunscreen formulations. Its mildness and good skin compatibility make it suitable for personal care applications.

SECTION 16: COMPARISON WITH OTHER PLASTICIZERS

Property DPGDB DOP (DEHP) DINP DOTP ATBC
Chemical Class Benzoate Ester Phthalate Phthalate Terephthalate Citrate
CAS Number 27138-31-4 117-81-7 68515-48-0 6422-86-2 77-90-7
Molecular Weight 326.39 g/mol 390.56 g/mol ~420 g/mol 390.56 g/mol 402.48 g/mol
Density (25°C) 1.144 g/cm³ 0.986 g/cm³ ~0.984 g/cm³ 0.984 g/cm³ 1.045 g/cm³
Volatility Very Low Low Very Low Very Low Low
PVC Compatibility Excellent Excellent Excellent Excellent Good
Plasticizing Efficiency High High High High Moderate
Migration Resistance Excellent Moderate Good Excellent Good
Extractability Excellent Moderate Good Excellent Good
Low Temperature Flexibility Good Excellent Excellent Excellent Good
Toxicity/Regulatory Non-toxic, non-phthalate Restricted Restricted in some applications Preferred alternative Preferred alternative
Environmental Status Environmentally friendly Phthalate concern Phthalate concern Preferred alternative Preferred alternative
Cost Moderate Low Low Moderate Higher

Description: Dipropylene Glycol Dibenzoate offers several advantages compared to conventional phthalate plasticizers. It is a non-phthalate, environmentally friendly alternative with low toxicity and good regulatory acceptance. Compared to DOP (DEHP) and DINP, DPGDB has higher density, lower volatility, and better migration resistance. Compared to DOTP and ATBC, DPGDB offers comparable performance with potentially better compatibility with polar polymers. Its high solvency power and broad compatibility make it an excellent choice for a wide range of applications.

SECTION 17: ADVANTAGES AND BENEFITS

Parameter Description
Environmental Friendliness Non-phthalate, environmentally friendly alternative to o-benzene plasticizers
Low Toxicity Low toxicity profile; suitable for sensitive applications (toys, gloves, medical)
Excellent Compatibility Compatible with a wide range of polar polymers (PVC, PU, acrylics, PS)
High Solvency Power High solvency for polar and moderately polar polymers and resins
Low Volatility Very low vapor pressure; provides permanent plasticization
Good Migration Resistance Resistant to migration; maintains properties over time
Excellent Extractability Resistance Resistant to extraction by water, oils, and solvents
Good Low-Temperature Performance Provides flexibility even at low temperatures
Excellent Heat Stability Stable at high processing temperatures
Good Aging Resistance Resistant to aging and UV degradation
Regulatory Acceptance Widely accepted in global regulations; REACH compliant
Versatility Suitable for adhesives, plastics, coatings, inks, sealants, and cosmetics

Description: Dipropylene Glycol Dibenzoate offers a wide range of advantages as a plasticizer. Its environmental friendliness, low toxicity, and excellent compatibility with polar polymers make it a preferred choice for phthalate-sensitive applications. Its high solvency power, low volatility, good migration resistance, and excellent extractability resistance ensure long-term plasticizing performance. It is suitable for a wide range of applications including adhesives, plastics, coatings, inks, sealants, and cosmetics. Its regulatory acceptance and REACH compliance facilitate global use.

SECTION 18: REGULATORY STATUS

Region / Authority Status Maximum Concentration Description
European Union Permitted No specific restriction REACH registered; not classified as SVHC
Turkey Permitted No specific restriction Compliant with EU legislation
USA (FDA) Permitted Indirect food contact FDA 21 CFR approved for specific applications
China Permitted No specific restriction Compliant with Chinese regulations
Japan Permitted No specific restriction Japanese regulations
REACH Registered EC 1907/2006 compliant
TSCA (USA) Listed Toxic Substances Control Act
EINECS (EU) 202-296-9 European Inventory of Existing Chemical Substances

Description: Dipropylene Glycol Dibenzoate is widely permitted in global regulations. It is REACH registered and not classified as a Substance of Very High Concern (SVHC). It is permitted for use in FDA-regulated applications for indirect food contact. Its non-phthalate, low-toxicity profile makes it suitable for applications requiring regulatory compliance.

SECTION 19: SAFETY AND TOXICOLOGICAL PROFILE

Parameter Value / Assessment Test System
Acute Oral Toxicity (LD50) > 5,000 mg/kg Rat
Acute Dermal Toxicity (LD50) > 2,000 mg/kg Rabbit
Acute Inhalation Toxicity (LC50) > 5 mg/L Rat
Skin Irritation Non-irritating (at use levels) Rabbit (Draize test)
Eye Irritation Non-irritating to mildly irritating Rabbit (Draize test)
Skin Sensitization Not a sensitizer Human Patch Test / GPMT
Mutagenicity Not mutagenic (Ames test negative) Ames Test / Micronucleus Test
Reproductive Toxicity Not classified Animal studies
Endocrine Disruption No potential concern In vitro / In vivo studies
Carcinogenicity Not classified (IARC, NTP) -
Bioaccumulation Potential Low Calculated

Description: Dipropylene Glycol Dibenzoate has a very low toxicity profile. Acute oral toxicity (LD50) is >5,000 mg/kg, indicating low toxicity. It is non-irritating to the skin and not a sensitizer. It is not classified as mutagenic, carcinogenic, or reproductive toxicant. It is not considered an endocrine disruptor. Bioaccumulation potential is low. The excellent safety profile makes it suitable for sensitive applications including toys, gloves, and cosmetic products.

SECTION 20: STORAGE, SHELF LIFE AND PACKAGING

Parameter Description
Storage Temperature 15 – 30°C (cool and dry)
Storage Conditions Well-ventilated, moisture-protected area
Light Protection Protect from direct sunlight and UV sources
Moisture Sensitivity Protect from excessive moisture (hygroscopic)
Materials to Avoid Strong oxidizing agents, strong acids, strong bases
Shelf Life 24 – 36 months (unopened, recommended conditions)
Degradation Signs Color change (darkening), acid value increase, odor change
Standard Packaging 200 kg, 220 kg HDPE drums
Bulk Packaging 1000 kg IBC (Intermediate Bulk Container)
Small Packaging (Upon Request) 20 kg, 25 kg, 50 kg
Packaging Material HDPE drums, IBC containers, PE-lined steel drums
Closure Recommendation Keep tightly closed when not in use

Description: Dipropylene Glycol Dibenzoate should be stored in a cool, dry place in its original packaging. It should be protected from excessive moisture as it is mildly hygroscopic. Contact with strong oxidizing agents, acids, and bases should be avoided. Shelf life is 24-36 months under recommended storage conditions. Degradation signs include color darkening, acid value increase, and odor change. Each package should bear the manufacturing date and batch number for traceability.

SECTION 21: TRANSPORTATION AND SHIPPING INFORMATION

Parameter Description
UN Number Not regulated (non-hazardous)
Hazard Class Not classified as dangerous goods
Packing Group Not applicable
Marine Pollutant No
Transport Classification  
ADR (Road) Not classified
RID (Rail) Not classified
ADN (Inland Waterway) Not classified
IMDG (Maritime) Not classified
IATA/ICAO (Air) Not classified
Transport Temperature Ambient temperature (15-30°C)
Transport Precautions Protect from moisture and excessive heat
Packaging Precautions Use leak-proof, sturdy packaging

Description: Dipropylene Glycol Dibenzoate is not classified as dangerous goods for transportation. It does not require UN number or hazard labeling. However, proper packaging should be used to prevent leakage and moisture ingress. Transport should be at ambient temperatures (15-30°C), and the product should be protected from excessive heat. The GTIP/HS code is 2918.29.00.00.00 (or specific depending on destination).

SECTION 22: ENVIRONMENTAL INFORMATION AND ECOTOXICOLOGY

Parameter Value / Assessment
Aquatic Toxicity (Fish, LC50, 96h) > 100 mg/L
Aquatic Toxicity (Daphnia, EC50, 48h) > 100 mg/L
Algal Toxicity (EC50, 72h) > 100 mg/L
Biodegradability Readily biodegradable (OECD 301F)
Bioaccumulation Potential Low
Hydrolysis Hydrolytically stable at neutral pH
Persistence Low (biodegradable)
Environmental Classification Not classified as hazardous to the environment
Water Hazard Class (WGK, Germany) Class 1 (slightly hazardous to water)

Description: Dipropylene Glycol Dibenzoate is readily biodegradable and has low toxicity to aquatic organisms. It has low bioaccumulation potential and does not persist in the environment. Compared to phthalate plasticizers, it has a more favorable environmental profile. It is classified as only slightly hazardous to water, supporting its use as an environmentally friendly alternative.

SECTION 23: QUALITY CERTIFICATES AND STANDARDS

Certificate / Standard Status Description
ISO 9001:2015 Certified Manufacturing facilities have quality management system
ISO 14001:2015 Certified Environmental management system (optional)
REACH (EC 1907/2006) Registered Compliant with EU chemical regulations
FDA 21 CFR Compliant Suitable for FDA-regulated applications
Kosher Upon request Certified according to Jewish standards
Certificate of Analysis (COA) Provided with each batch Includes binding specifications
Safety Data Sheet (SDS) Available Current 16-section document
Technical Data Sheet (TDS) Available Comprehensive technical information
Good Manufacturing Practices (GMP) Compliant Manufacturing quality standards

SECTION 24: DISCLAIMER AND LEGAL NOTICE

Item Description
Information Purpose This Technical Data Sheet (TDS) is for informational purposes only and does not constitute a binding specification.
Typical Values Values stated herein are based on typical laboratory results and may vary slightly between production batches.
Binding Data For binding specifications, the Certificate of Analysis (COA) for each batch should be requested.
User Responsibility The user is solely responsible for determining the suitability of the product for the intended application and ensuring compliance with all applicable regulations.
SDS Requirement A current Safety Data Sheet (SDS) should be requested from the supplier prior to use.
Safety Information Safety information in this document is based on current knowledge but does not constitute a guarantee of the product's health and safety risks.
Regulatory Changes The user is responsible for monitoring local and international regulatory changes.
Product Quality Product quality is guaranteed in accordance with the standards specified in this document.
License / Patents This document does not grant any license or patent rights for use of the product.
Compatibility Product compatibility with specific formulations should be confirmed through testing.

DISCLAIMER (LEGAL NOTICE): This Technical Data Sheet (TDS) is for informational purposes only and does not constitute a binding specification. The values stated herein are based on typical laboratory results. The user is solely responsible for determining the suitability of the product for the intended application and for ensuring compliance with all local regulations. A current Safety Data Sheet (SDS) and Certificate of Analysis (COA) should be requested prior to use. Product compatibility with specific formulations should be confirmed through testing. This document does not grant any license or patent rights for use of the product.

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