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Send EmailEthylene Diamine Tetra Methylene Phosphonic Acid, Ethylenediamine Tetramethylene Phosphonic Acid, EDTMP, EDTMPA, EDITEMPA, 1429-50-1
ETHYLENEDIAMINE TETRA(METHYLENEPHOSPHONIC ACID) (EDTMPA)
CAS 1429-50-1 | C₆H₂₀N₂O₁₂P₄
SECTION 1: PRODUCT IDENTITY AND DEFINITION
| Parameter | Description |
|---|---|
| Product Name | Ethylenediamine Tetra(methylenephosphonic Acid) |
| Other Names | EDTMPA, EDITEMPA, EDTMP, Ethylenebis(nitrilodimethylene)tetraphosphonic acid, Dequest 2041 |
| Chemical Formula | C₆H₂₀N₂O₁₂P₄ |
| Molecular Weight | 436.12 g/mol |
| CAS Number | 1429-50-1 |
| Chemical Class | Organophosphonate / Aminophosphonic Acid |
| Appearance | White Crystalline Powder |
| Source | Synthetic |
Description: EDTMPA (Ethylenediamine Tetra(methylenephosphonic Acid)) is a powerful organophosphonate chelating agent belonging to the aminophosphonic acid family. It is a white crystalline powder with strong chelation capacity, particularly effective for copper ions. It exhibits excellent scale and corrosion inhibition properties, low concentration effectiveness, and high temperature resistance. It is widely used in water treatment, industrial cleaning, electronics, and pharmaceutical applications. EDTMPA is a member of the phosphonate family, which is characterized by high water solubility, strong metal ion binding capacity, and corrosion prevention properties.
SECTION 2: SYNONYMS AND OTHER NAMES
| No | Synonym / Other Name |
|---|---|
| 1 | Ethylenediamine Tetra(methylenephosphonic Acid) |
| 2 | EDTMPA |
| 3 | EDITEMPA |
| 4 | EDTMP |
| 5 | Ethylenebis(nitrilodimethylene)tetraphosphonic acid |
| 6 | Dequest 2041 |
| 7 | 1429-50-1 |
| 8 | 2,2',2'',2'''-(Ethane-1,2-diyldinitrilo)tetrakis(methylphosphonic acid) |
| 9 | N,N,N',N'-Tetrakis(phosphonomethyl)ethylenediamine |
| 10 | Ethylenediamine-N,N,N',N'-tetrakis(methylenephosphonic acid) |
SECTION 3: CHEMICAL STRUCTURE AND PROPERTIES
| Parameter | Description |
|---|---|
| Chemical Family | Organophosphonate / Aminophosphonic Acid |
| Structure | Ethylenediamine backbone with four methylenephosphonic acid groups (-CH₂PO₃H₂) |
| Functional Groups | Four Phosphonic Acids (-PO₃H₂), Two Amines (-NH-) |
| Chelation | Octadentate ligand; forms highly stable complexes with metal ions |
| pH Dependence | Anionic character increases with pH (phosphonate ionization) |
Structural Formula:
(HO₃PCH₂)₂N - CH₂ - CH₂ - N(CH₂PO₃H₂)₂
N,N,N',N'-Tetrakis(phosphonomethyl)ethylenediamine (EDTMPA)
Key Characteristics:
-
Four phosphonic acid groups: Provide exceptional metal ion binding and chelation
-
Two amine groups: Additional coordination sites
-
Ethylenediamine backbone: Provides structural stability
-
Octadentate ligand: Can form up to 8 coordinate bonds with metal ions
-
High chelation capacity: Particularly effective for copper, calcium, and other metal ions
-
Thermal stability: Stable at high temperatures
-
Low concentration effectiveness: Effective at very low concentrations
SECTION 4: PHYSICAL AND CHEMICAL PROPERTIES
| Parameter | Specification | Typical Value | Test Method |
|---|---|---|---|
| Physical State (25°C) | Solid (Crystalline Powder) | - | Visual |
| Appearance | White Crystalline Powder | - | Visual |
| Odor | Slight characteristic | - | Organoleptic |
| Chemical Formula | C₆H₂₀N₂O₁₂P₄ | - | - |
| Molecular Weight | 436.12 g/mol | - | - |
| CAS Number | 1429-50-1 | - | - |
| Melting Point | 215 – 217°C | ~216°C | DSC |
| Boiling Point | 878.7 ± 75.0°C (estimated) | - | - |
| Density | 1.993 ± 0.06 g/cm³ (estimated) | ~1.99 g/cm³ | - |
| Water Solubility | Slightly soluble in water | - | - |
| Solubility in Ammonia | Readily soluble | - | - |
| Acid Value | - | - | Titration |
| Phosphorus Content | ~28.4% | - | Titration |
| Chelation Capacity | Very high | - | - |
| pH Stability | Wide pH range | - | - |
| Thermal Stability | High | - | TGA |
SECTION 5: CHELATION MECHANISM
| Parameter | Description |
|---|---|
| Chelating Agent | Octadentate ligand (8-coordinate) |
| Donor Atoms | 4 Phosphonate Oxygen atoms + 2 Amine Nitrogen atoms |
| Metal Ion Binding | Forms highly stable complexes with metal ions |
| Stability Constants (Log K) | |
| Cu²⁺ | Very High |
| Ca²⁺ | High |
| Fe³⁺ | Very High |
| Zn²⁺ | High |
| Optimal pH Range | 2.0 – 14.0 |
| Chelation Mechanism | EDTMPA + Mⁿ⁺ → [EDTMPA-M]⁽⁴⁻ⁿ⁾ + nH⁺ |
| Lattice Distortion | Distorts crystal lattice of scale-forming salts |
Description: EDTMPA acts by forming highly stable, water-soluble complexes with metal ions. The chelation process involves the coordination of the metal ion by the four phosphonate groups and the two amine nitrogen atoms of the EDTMPA molecule. This encapsulating structure effectively "traps" the metal ion, preventing it from participating in undesirable chemical reactions such as precipitation, scale formation, and catalysis. EDTMPA is particularly effective for copper ions, making it valuable in electronics and metal treatment applications.
SECTION 6: COMPARISON WITH OTHER PHOSPHONATES
| Property | EDTMPA | ATMP | DTMPA | HEDP | PBTC |
|---|---|---|---|---|---|
| CAS Number | 1429-50-1 | 6419-19-8 | 15827-60-8 | 2809-21-4 | 37971-36-1 |
| Chemical Formula | C₆H₂₀N₂O₁₂P₄ | C₃H₁₂NO₉P₃ | C₉H₂₈N₃O₁₅P₅ | C₂H₈O₇P₂ | C₇H₁₁O₉P |
| Molecular Weight | 436.12 | 299.05 | 573.21 | 206.03 | 270.13 |
| Active Groups | 4 Phosphonic + 2 Amine | 3 Phosphonic | 5 Phosphonic | 2 Phosphonic | 1 Phosphonic + 3 Carboxylic |
| Chelation Capacity | Very High | High | Very High | High | High |
| Copper Binding | Excellent | Good | Good | Moderate | Moderate |
| Calcium Binding | Very High | High | Very High | High | Very High |
| Thermal Stability | High | Good | Good | Good (250°C) | Excellent (300°C) |
| pH Range | Wide (2-14) | Wide | Wide | Wide (4-14) | Wide |
| Dosage Effectiveness | Very Low | Low | Low | Low | Low |
| Lattice Distortion | Good | Good | Moderate | Good | Excellent |
| Main Applications | Water treatment, electronics, pharmaceuticals | Water treatment, cleaning, coatings | Boilers, cooling towers, detergents | Water treatment, detergents, cosmetics | Water treatment, oilfield |
SECTION 7: APPLICATIONS
| Industry | Application | Function / Benefit | Typical Dosage |
|---|---|---|---|
| Water Treatment | |||
| Cooling Water Systems | Scale & corrosion inhibitor | Prevents scale formation and corrosion | 1 – 10 mg/L |
| Boilers | Scale inhibitor | Prevents scale formation in boilers | 1 – 10 mg/L |
| Municipal Water Systems | Scale inhibitor | Prevents scale formation in water distribution | 1 – 5 mg/L |
| Electronics Industry | |||
| Semiconductor Chip Cleaning | Chelating agent | Removes metal ions from surfaces | 0.1 – 1.0% |
| Printed Circuit Boards | Chelating agent | Removes metal ions | 0.1 – 1.0% |
| Industrial Cleaning | |||
| Descaling Formulations | Scale remover, chelating agent | Removes scale deposits | 5 – 20% |
| Metal Surface Treatment | Chelating agent | Removes metal ions | 1 – 5% |
| Pharmaceuticals | |||
| Radioactive Element Carriers | Chelating agent | Binds radioactive elements | Appropriate dosage |
| Diagnostic Imaging | Chelating agent | Binds contrast agents | Prescription dosage |
| Detergents | |||
| Household Detergents | Scale inhibitor, chelating agent | Prevents hard water effects | 0.1 – 1.0% |
| Industrial Cleaners | Chelating agent | Binds metal ions | 0.1 – 1.0% |
| Paints & Coatings | |||
| Coating Formulations | Dispersant, chelating agent | Improves pigment dispersion | 0.1 – 0.5% |
SECTION 8: ADVANTAGES AND BENEFITS
| Advantage | Description |
|---|---|
| Excellent Chelation Capacity | Very high metal ion binding capacity; particularly effective for copper ions |
| Wide pH Range | Stable and effective across a wide pH range (2-14) |
| High Thermal Stability | Effective at high temperatures |
| Low Concentration Effectiveness | Effective at very low concentrations |
| Strong Scale Inhibition | Effective against calcium carbonate and other scales |
| Corrosion Inhibition | Prevents corrosion in water systems |
| Lattice Distortion | Distorts crystal lattice of scale-forming salts |
| Pharmaceutical Applications | Used as radioactive element carrier and in diagnostic imaging |
| Electronics Applications | Used in semiconductor chip cleaning |
| Versatility | Used in water treatment, electronics, pharmaceuticals, cleaning, and coatings |
SECTION 9: REGULATORY STATUS
| Region / Authority | Status | Description |
|---|---|---|
| European Union | Permitted | Water treatment chemical, cleaning agent |
| Turkey | Permitted | Compliant with EU legislation |
| USA (EPA) | Permitted | Approved as water treatment chemical |
| Japan | Permitted | Approved as water treatment chemical |
| Canada | Permitted | Health Canada approved |
| REACH | Registered | Compliant with EU chemical regulations |
SECTION 10: SAFETY AND TOXICOLOGICAL PROFILE
| Parameter | Assessment |
|---|---|
| Acute Oral Toxicity (LD50) | > 2,000 mg/kg (low toxicity) |
| Acute Dermal Toxicity | Low toxicity |
| Skin Irritation | May be irritating |
| Eye Irritation | May cause severe irritation |
| Skin Sensitization | Low potential |
| Carcinogenicity | Not classified (IARC, NTP) |
| Mutagenicity | Not mutagenic |
| Reproductive Toxicity | Not classified |
| Aquatic Toxicity | Low – Moderate |
| Biodegradability | Biodegradable |
Safety Recommendations:
-
S26: In case of eye contact, rinse immediately with plenty of water and seek medical advice
-
S36/37/39: Wear suitable protective clothing, gloves, and eye/face protection
-
S45: In case of accident, seek medical advice
-
PPE: Chemical resistant gloves, safety goggles, protective clothing
SECTION 11: STORAGE AND SHELF LIFE
| Parameter | Information |
|---|---|
| Storage Temperature | 5 – 30°C (cool, dry) |
| Storage Conditions | Cool, dry, well-ventilated area |
| Container Requirements | Sealed containers; protect from moisture |
| Protect From | Moisture, humidity, contamination |
| Shelf Life | 24 – 36 months (under proper storage) |
| Degradation Signs | Caking, discoloration, moisture absorption |
| Compatibility | Compatible with most water treatment chemicals |
SECTION 12: QUALITY CERTIFICATES AND STANDARDS
| Certificate / Standard | Status | Description |
|---|---|---|
| ISO 9001:2015 | Certified | Quality management system |
| ISO 14001:2015 | Certified | Environmental management system |
| REACH | Registered | EU chemical regulation compliance |
| Certificate of Analysis (COA) | Provided with each batch | Includes binding specifications |
| Safety Data Sheet (SDS) | Available | Current 16-section document |
| Technical Data Sheet (TDS) | Available | Comprehensive technical information |
| GMP | Compliant | Manufacturing quality standards |
SECTION 13: DISCLAIMER AND LEGAL NOTICE
| Item | Description |
|---|---|
| Information Purpose | This Technical Data Sheet (TDS) is for informational purposes only and does not constitute a binding specification. |
| Typical Values | Values stated herein are based on typical laboratory results and may vary slightly between batches. |
| Binding Data | For binding specifications, the Certificate of Analysis (COA) for each batch should be requested. |
| User Responsibility | The user is solely responsible for determining the suitability of the product for the intended application and ensuring compliance with all applicable regulations. |
| SDS Requirement | A current Safety Data Sheet (SDS) should be requested from the supplier prior to use. |
| Safety Information | Safety information in this document is based on current knowledge but does not constitute a guarantee of the product's health and safety risks. |
| Regulatory Changes | The user is responsible for monitoring local and international regulatory changes. |
| Product Quality | Product quality is guaranteed in accordance with the standards specified in this document. |
| License / Patents | This document does not grant any license or patent rights for use of the product. |
| Side Effects | May cause skin and eye irritation; appropriate protective measures should be taken. |
DISCLAIMER (LEGAL NOTICE): This Technical Data Sheet (TDS) is for informational purposes only and does not constitute a binding specification. The values stated herein are based on typical laboratory results. The user is solely responsible for determining the suitability of the product for the intended application and for ensuring compliance with all local regulations. A current Safety Data Sheet (SDS) and Certificate of Analysis (COA) should be requested prior to use. May cause skin and eye irritation; appropriate protective measures should be taken. This document does not grant any license or patent rights for use of the product.
