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Myristyl Alcohol, Myristic Alcohol, Tetradecanol, Tetradecyl Alcohol, Alcohol C-14, 112-72-1

Myristyl Alcohol, Myristic Alcohol, Tetradecanol, Tetradecyl Alcohol, Alcohol C-14, 112-72-1

MYRISTYL ALCOHOL (TETRADECANOL) - 112-72-1

SECTION 1: PRODUCT IDENTITY AND DEFINITION

Parameter Description
Product Name Myristyl Alcohol
Chemical Name (IUPAC) Tetradecan-1-ol
Other Names Myristic Alcohol, Tetradecanol, Alcohol C-14, 1-Tetradecanol, n-Tetradecanol, Tetradecyl Alcohol
Chemical Formula C₁₄H₃₀O
Molecular Weight 214.39 g/mol
CAS Number 112-72-1
EC Number 204-000-3
Chemical Class Fatty Alcohol / Long-Chain Primary Alcohol
REACH Status Registered and compliant
TSCA (USA) Listed

Description: Myristyl Alcohol is a saturated, straight-chain fatty alcohol produced by the hydration of myristic acid. Myristic acid can be obtained from natural sources such as coconut oil, palm kernel oil, and nutmeg oil (from which it derives its name). It appears as a white, waxy, crystalline solid at room temperature. In cosmetic and personal care products, it functions as a thickening agent, emulsion stabilizer, and emollient.

SECTION 2: SYNONYMS AND OTHER NAMES

No Synonym / Other Name
1 Myristyl Alcohol
2 Myristic Alcohol
3 Tetradecanol
4 Alcohol C-14
5 1-Tetradecanol
6 n-Tetradecanol
7 Tetradecyl Alcohol
8 Tetradecan-1-ol
9 C14 Alcohol
10 Myristyl Alkohol (German)
11 Alcool Myristylique (French)
12 Miristil Alkol (Turkish)
13 Miristik Alkol (Turkish)
14 Tetradecyl Alcohol
15 n-Tetradecyl Alcohol
16 112-72-1
17 Fatty Alcohol C14
18 C14 Linear Primary Alcohol
19 Myristyl Monohydric Alcohol
20 Tetradecane-1-ol

SECTION 3: CHEMICAL STRUCTURE AND MOLECULAR PROPERTIES

Parameter Description
Chemical Family Fatty Alcohols / Long-Chain Primary Alcohols
Structure Linear saturated hydrocarbon chain with terminal primary alcohol group
Molecular Structure CH₃-(CH₂)₁₂-CH₂OH
SMILES Notation CCCCCCCCCCCCCCO
InChI InChI=1S/C14H30O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15/h15H,2-14H2,1H3
InChI Key DTLBZHAOWOBZOS-UHFFFAOYSA-N
Functional Groups Primary Alcohol (-CH₂OH), Long Hydrocarbon Chain
Log P (Hydrophobicity) 5.95 (highly lipophilic)
HLB (Hydrophilic-Lipophilic Balance) ~1.5 (very low, oil-soluble)

Structural Formula:

text

CH₃ - CH₂ - CH₂ - CH₂ - CH₂ - CH₂ - CH₂ - CH₂ - CH₂ - CH₂ - CH₂ - CH₂ - CH₂ - CH₂ - OH
       |
       └─── 14 Carbon Chain (Tetradecyl) ───┘

Description: Myristyl Alcohol is a long-chain primary fatty alcohol with a 14-carbon saturated alkyl chain. The terminal hydroxyl group (-OH) provides a slight polar character, allowing it to function as a non-ionic surfactant and emulsifier. However, the long hydrocarbon chain makes it highly lipophilic (Log P = 5.95), giving it excellent oil solubility and emollient properties.

SECTION 4: PHYSICAL APPEARANCE AND FORM

Parameter Specification Typical Value Test Method
Physical State Solid (waxy, crystalline) - Visual
Color White to off-white - Visual
Odor Mild, characteristic, waxy - Organoleptic
Form Flakes, pellets, or pastilles - Visual
Crystal Structure Waxy crystalline - Microscopic
Dropping Point - ~38-40 °C -
Acid Value ≤ 0.5 mg KOH/g < 0.2 Titration
Saponification Value ≤ 2.0 mg KOH/g < 1.0 Titration

Description: Myristyl Alcohol is a white to off-white, waxy, crystalline solid at room temperature. It has a mild, characteristic waxy odor. It is supplied in the form of flakes, pellets, or pastilles for ease of handling and incorporation into formulations. The crystalline structure gives it a smooth, elegant texture when incorporated into creams and lotions.

SECTION 5: MELTING POINT AND THERMAL PROPERTIES

Parameter Specification Typical Value Test Method
Melting Point Range 36 – 40 °C 38 – 39 °C DSC / Capillary Tube
Melting Point Onset ≥ 36 °C 37.5 °C Capillary Tube
Melting Point Endset ≤ 40 °C 39.0 °C Capillary Tube
Boiling Point ~260 – 290 °C 289 °C ASTM D86
Boiling Point (10 mmHg) ~180-190 °C - -
Flash Point > 150 °C ~160 °C ASTM D93
Melting Enthalpy (ΔHm) ~55 kJ/mol - DSC
Specific Heat Capacity ~2.2 J/g·°C - DSC

Description: Myristyl Alcohol has a melting point range of 36-40°C, which is slightly above body temperature. This allows it to melt upon skin contact, providing a smooth, luxurious feel in cosmetic formulations. The narrow melting range indicates high purity. It has a relatively high boiling point (289°C) and flash point (>150°C), making it thermally stable during processing.

SECTION 6: DENSITY AND BULK PROPERTIES

Parameter Specification Typical Value Test Method
Density (20°C) - ~0.824 g/cm³ Pycnometer
Density (Solid, 25°C) - ~0.82 g/cm³ Pycnometer
Density (Liquid, 50°C) - ~0.80 g/cm³ Pycnometer
Bulk Density (Flakes) - ~0.40 – 0.50 g/cm³ Graduated Cylinder
Bulk Density (Pellets) - ~0.50 – 0.60 g/cm³ Graduated Cylinder
Specific Gravity (60°C/25°C) - 0.815 – 0.825 Hydrometer

Description: Myristyl Alcohol has a density of approximately 0.824 g/cm³ at 20°C in its liquid state. As a solid, the density is approximately 0.82 g/cm³. The bulk density varies depending on the physical form (flakes vs. pellets), which affects handling, storage, and blending operations. The density decreases with increasing temperature, as with most fatty alcohols.

SECTION 7: SOLUBILITY AND MISCIBILITY

Solvent / Medium Solubility / Miscibility (25°C) Temperature Effect
Water Practically insoluble (< 0.01 g/L) Negligible
Ethanol (Absolute) Soluble (~50-100 g/L) Increases with heat
Methanol Soluble (~40-80 g/L) Increases with heat
Isopropyl Alcohol Soluble (~30-60 g/L) Increases with heat
Acetone Soluble (~100-200 g/L) Increases with heat
Mineral Oil Highly soluble
Vegetable Oils Highly soluble
Silicone Oils Partially soluble Increases with heat
Propylene Glycol Slightly soluble Increases with heat
Glycerin Insoluble
Nonionic Surfactants Compatible
Anionic Surfactants Compatible
Cationic Surfactants Compatible

Description: Myristyl Alcohol is practically insoluble in water due to its long hydrophobic hydrocarbon chain. It is soluble in alcohols (ethanol, methanol, isopropanol), acetone, and most organic solvents. It is highly soluble in oils, including mineral oil and vegetable oils, which makes it an excellent emollient and oil-phase component. The solubility in polar solvents increases with temperature.

SECTION 8: PURITY AND ANALYTICAL SPECIFICATIONS

Parameter Specification Typical Value Test Method
Purity (GC) ≥ 95.0% 97.0 – 99.0% GC (FID)
Myristyl Alcohol Content ≥ 95.0% 97.0 – 98.5% GC
C12 Alcohol Content ≤ 3.0% < 2.0% GC
C16 Alcohol Content ≤ 3.0% < 2.0% GC
Melting Point 36 – 40 °C 38 – 39 °C Capillary Tube
Acid Value ≤ 0.5 mg KOH/g < 0.2 USP <401>
Saponification Value ≤ 2.0 mg KOH/g < 1.0 USP <401>
Iodine Value ≤ 1.0 g I₂/100g < 0.5 USP <401>
Hydroxyl Value 258 – 266 mg KOH/g 260 – 264 USP <401>
Loss on Drying ≤ 0.5% < 0.2% USP <731>
Ash Content (Sulfated) ≤ 0.1% < 0.05% USP <281>
Color (APHA, Melted) ≤ 50 < 20 ASTM D1209
Heavy Metals (Pb) ≤ 10 ppm < 5 ppm USP <231>
Arsenic ≤ 2 ppm < 1 ppm USP <211>
Water Content (KF) ≤ 0.5% < 0.2% Karl Fischer
Cloud Point - ~35-37 °C -
Gardner Color ≤ 1 < 0.5 ASTM D1544

Description: Myristyl Alcohol is supplied in high purity (≥95% C14 alcohol). The purity and carbon chain distribution are determined by GC analysis. The hydroxyl value (258-266 mg KOH/g) confirms the presence of the primary alcohol group. Low acid and saponification values indicate high purity and low contamination with free fatty acids and esters. The iodine value (<1.0) confirms the saturated nature of the molecule.

SECTION 9: SPECTROSCOPIC PROPERTIES

Parameter Value / Description
IR (ATR) Characteristic Bands 3300-3350 cm⁻¹ (O-H stretch, broad), 2950-2860 cm⁻¹ (C-H aliphatic stretch), 1460-1470 cm⁻¹ (CH₂ bending), 1380-1390 cm⁻¹ (CH₃ bending), 1050-1070 cm⁻¹ (C-O primary alcohol stretch), 720-730 cm⁻¹ (CH₂ rocking, long chain)
¹H-NMR (CDCl₃) δ 3.63 (t, 2H, CH₂OH), 1.55 (m, 2H, CH₂-CH₂OH), 1.35-1.20 (m, 22H, CH₂ chain), 0.88 (t, 3H, terminal CH₃)
¹³C-NMR (CDCl₃) δ 63.0 (CH₂OH), 33.0 (CH₂-CH₂OH), 32.0-22.5 (CH₂ chain), 14.1 (terminal CH₃)
Mass Spectrum (MS - EI) m/z 214 [M⁺], 196 [M-H₂O]⁺, 168, 154, 125, 111, 97, 83, 69, 57, 43
GC-MS Retention Index ~1700 (on non-polar column)

Description: These spectroscopic data are used for structural identification and purity control of Myristyl Alcohol. The IR spectrum shows the characteristic broad O-H stretch at 3300-3350 cm⁻¹ and the C-O stretch at 1050-1070 cm⁻¹ for primary alcohol. The ¹H-NMR spectrum clearly shows the terminal methyl group at δ 0.88 ppm and the methylene protons adjacent to the hydroxyl group at δ 3.63 ppm. The mass spectrum shows the molecular ion at m/z 214.

SECTION 10: THERMAL PROPERTIES AND STABILITY

Parameter Value / Description
Decomposition Onset Temperature ~250 °C (by TGA)
Maximum Decomposition Rate ~300-320 °C (by TGA)
Melting Enthalpy (ΔHm) ~55 kJ/mol
Crystallization Temperature ~32-35 °C (on cooling)
Thermal Stability Stable up to 150°C for processing
pH Stability Stable in pH 3 – 12 range
Light Stability Stable under normal light conditions
Hydrolytic Stability Stable in aqueous systems
Oxidative Stability Susceptible to oxidation at high temperatures; stable at room temperature
Storage Stability Stable when stored in sealed containers away from heat and light

Description: Myristyl Alcohol is thermally stable up to 150°C, which is sufficient for most cosmetic and personal care processing conditions. It begins to decompose above 250°C. It is stable across a wide pH range (pH 3-12). While it is resistant to hydrolysis, it may be susceptible to oxidation at elevated temperatures, requiring the use of antioxidants in long-term storage or high-temperature applications. It crystallizes upon cooling at approximately 32-35°C.

SECTION 11: FUNCTIONAL PROPERTIES AND MECHANISM

Property Description / Mechanism
Emollient Forms a protective, occlusive film on the skin surface, preventing moisture loss and providing a soft, smooth feel. The long hydrocarbon chain allows it to penetrate the stratum corneum, replenishing lipid content.
Emulsion Stabilizer / Co-emulsifier Positions itself at the oil-water interface, lowering interfacial tension and stabilizing emulsions. It works synergistically with primary emulsifiers to enhance emulsion stability. Prevents coalescence of oil droplets and phase separation.
Thickener / Viscosity Modifier Increases the viscosity of oil phases and formulations. Forms a crystalline network that imparts structure and body to creams and lotions, improving spreadability and application properties.
Occlusive Agent Forms a barrier on the skin surface, reducing transepidermal water loss (TEWL). Provides long-lasting moisturization.
Texture Enhancer Imparts a smooth, elegant, non-greasy feel to formulations. Reduces the watery feel of lotions and provides a soft, waxy after-feel.
Penetration Enhancer Aids in the penetration of other active ingredients into the skin by disrupting the stratum corneum lipid barrier temporarily.

Description: Myristyl Alcohol is a multifunctional ingredient. As an emollient, it softens and soothes the skin. As an emulsion stabilizer, it prevents the separation of oil and water phases, improving product stability. As a thickener, it provides body and structure to formulations, improving spreadability. Its occlusive properties help retain moisture in the skin. The combination of these properties makes it a versatile and valuable ingredient in cosmetic formulations.

SECTION 12: COSMETIC AND PERSONAL CARE APPLICATIONS

Application Category Function / Benefit Typical Use Level
Skin Care Products    
Moisturizing Creams Emollient, thickener, emulsion stabilizer 1.0 – 5.0%
Body Lotions Emollient, thickener, texture enhancer 1.0 – 3.0%
Night Creams Emollient, occlusive moisturizer 2.0 – 5.0%
Hand Creams Emollient, thickener, protective barrier 2.0 – 5.0%
Facial Moisturizers Emollient, texture enhancer 1.0 – 3.0%
Sunscreens Emulsion stabilizer, thickener 1.0 – 3.0%
Anti-aging Creams Emollient, penetration enhancer 1.0 – 3.0%
Hair Care Products    
Hair Conditioners Emollient, thickener, detangling agent 0.5 – 3.0%
Hair Masks Emollient, smoothing agent 1.0 – 3.0%
Leave-in Conditioners Emollient, texture enhancer 0.5 – 2.0%
Shampoos (Mild) Thickener, foam stabilizer 0.5 – 2.0%
Decorative Cosmetics    
Foundations Emulsion stabilizer, texture enhancer 1.0 – 3.0%
Lipsticks Thickener, texture enhancer, gloss 2.0 – 5.0%
Cream Blushes Emollient, thickener 1.0 – 3.0%
Other Personal Care    
Deodorants (Sticks/Rolls) Thickener, texture enhancer 1.0 – 3.0%
Shaving Creams Emollient, foam stabilizer 1.0 – 3.0%
Baby Care Products Emollient, gentle moisturizer 1.0 – 3.0%
Pharmaceutical Ointments Emollient, penetration enhancer 2.0 – 10.0%

Formulation Recommendations: Myristyl Alcohol is typically added to the oil phase of emulsions. For stable emulsions, it should be melted and mixed with other oil-phase components before emulsification. It is compatible with most nonionic, anionic, and cationic surfactants. The recommended use level is 0.5-5.0% depending on the desired consistency and application. For thickened formulations, it is often combined with other fatty alcohols such as Cetyl Alcohol or Stearyl Alcohol.

SECTION 13: PHARMACEUTICAL AND MEDICAL APPLICATIONS

Application Function / Description Typical Use Level
Topical Ointments Emollient, penetration enhancer, thickener 2.0 – 10.0%
Transdermal Delivery Systems Penetration enhancer for drug delivery 2.0 – 10.0%
Medicated Creams Emollient, emulsion stabilizer 2.0 – 5.0%
Suppository Bases Hardening agent, texture modifier 5.0 – 15.0%
Vaginal Creams Emollient, thickener 1.0 – 5.0%
Dermatological Products Skin conditioning, emollient 1.0 – 5.0%
Wound Care Products Emollient, protective barrier 1.0 – 5.0%

Description: Myristyl Alcohol is widely used in pharmaceutical formulations, particularly in topical ointments and transdermal delivery systems. Its ability to enhance skin penetration makes it valuable for drug delivery applications. It is used as a penetration enhancer to increase the absorption of active pharmaceutical ingredients through the skin. In suppository formulations, it acts as a hardening agent to provide the required consistency and melting characteristics.

SECTION 14: SOURCES AND PRODUCTION

Parameter Description
Natural Sources Coconut oil, palm kernel oil, nutmeg oil, milk fat, butterfat
Extraction Method Hydrolysis of triglycerides followed by fractional distillation and hydrogenation/reduction
Synthetic Route Hydrogenation of myristic acid (tetradecanoic acid) or reduction of methyl myristate
Production Process 1. Extraction of oils from natural sources (coconut, palm kernel)
2. Hydrolysis to obtain mixed fatty acids
3. Fractional distillation to isolate myristic acid
4. Catalytic hydrogenation/reduction to convert myristic acid to myristyl alcohol
5. Purification by distillation or crystallization
Reaction Equation CH₃(CH₂)₁₂COOH + H₂ → CH₃(CH₂)₁₂CH₂OH
Production Capacity Varies by manufacturer

Description: Myristyl Alcohol is produced primarily from natural sources. The major sources are coconut oil and palm kernel oil, which contain significant amounts of myristic acid (approximately 14-20% in coconut oil and 16-20% in palm kernel oil). The production process involves extraction of the oil, hydrolysis to release fatty acids, fractional distillation to isolate myristic acid, and catalytic hydrogenation to convert the acid to the primary alcohol. Purification is achieved through distillation or crystallization.

SECTION 15: REGULATORY STATUS AND HALAL/KOSHER CONSIDERATIONS

Parameter Description
EU Cosmetics Regulation Permitted for use; no restrictions
FDA (USA) GRAS (Generally Recognized as Safe) for cosmetic use
CIR (Cosmetic Ingredient Review) Safe for use in cosmetics
REACH Registered and compliant
Halal Status Permitted if derived from plant sources (coconut, palm kernel). If derived from animal sources (e.g., milk fat), must be from halal-certified animals and processed according to Islamic guidelines. Synthetic production is generally halal.
Kosher Status Permitted if derived from kosher-certified plant sources. Synthetic production can be kosher certified.
Global Regulations Permitted in cosmetics worldwide with no significant restrictions

Halal Guidelines for Myristyl Alcohol:

  • Plant Source (Coconut, Palm Kernel): Generally considered halal if processed without contamination with haram substances.

  • Animal Source (Milk Fat): Must come from halal-certified animals (e.g., cows, goats) and processed according to Islamic requirements.

  • Synthetic Source: Generally halal as long as no haram substances are used in the synthesis process.

  • Contamination: Must be free from cross-contamination with haram substances during production and packaging.

Recommendation: If halal compliance is required, it is recommended to:

  1. Verify the source of the myristyl alcohol (plant vs. animal vs. synthetic)

  2. Request halal certification from the supplier

  3. Ensure the production facility follows halal guidelines

  4. Confirm that no haram additives or processing aids are used

SECTION 16: SAFETY AND TOXICOLOGICAL PROFILE

Parameter Value / Assessment Test System
Acute Oral Toxicity (LD50) > 5,000 mg/kg Rat
Acute Dermal Toxicity (LD50) > 2,000 mg/kg Rabbit
Acute Inhalation Toxicity (LC50) > 5 mg/L Rat
Skin Irritation Non-irritating (at use levels) Rabbit (Draize test)
Eye Irritation Non-irritating to mildly irritating Rabbit (Draize test)
Skin Sensitization Not a sensitizer Human Patch Test / GPMT
Phototoxicity Not phototoxic In vitro / In vivo studies
Carcinogenicity Not classified (IARC, NTP) -
Mutagenicity Not mutagenic (Ames test negative) Ames Test / Micronucleus Test
Reproductive Toxicity Not classified Animal studies
Endocrine Disruption No potential concern In vitro studies
NOAEL > 1,000 mg/kg/day Rat (chronic studies)
Comedogenicity Moderate (may clog pores in susceptible individuals) Clinical observations
Skin Penetration Low (due to long hydrocarbon chain) In vitro skin penetration studies
Bioaccumulation Potential Low (metabolized in the body) -

Description: Myristyl Alcohol has an excellent safety profile. It has very low acute oral and dermal toxicity (LD50 > 5,000 mg/kg). It is non-irritating to the skin and non-sensitizing. It is not classified as carcinogenic, mutagenic, or reproductive toxicant. It is not considered an endocrine disruptor. However, like many fatty alcohols, it is moderately comedogenic (pore-clogging potential) and may cause breakouts in acne-prone individuals at high concentrations. At typical use levels (1-5%), it is well-tolerated.

SECTION 17: ADVANTAGES AND DISADVANTAGES

Parameter Description
Advantages  
Excellent Emollient Properties Provides soft, smooth, non-greasy skin feel
Emulsion Stabilizer Prevents phase separation and improves shelf life
Thickening Properties Adds body and structure to formulations
Versatility Suitable for multiple product types (skin, hair, cosmetics)
Natural Source Can be derived from renewable plant sources (coconut, palm kernel)
Non-Sensitizing Low allergenic potential
Cost-Effective Relatively inexpensive compared to other fatty alcohols
Good Thermal Stability Stable during hot processing
pH Stability Stable across a wide pH range
Enhances Penetration Aids in delivery of active ingredients
   
Disadvantages  
Comedogenic Potential May clog pores in acne-prone individuals
Water Insolubility Requires incorporation into oil phase
Crystalline Nature Requires melting during processing (above 38°C)
Waxy Texture May feel heavy in some formulations
Oxidative Susceptibility May require antioxidant protection at high temperatures
Crystallization May recrystallize upon cooling, affecting texture if not properly processed
Halal Considerations Source-dependent; requires verification for halal compliance

Description: Myristyl Alcohol offers many advantages as a multifunctional ingredient, including excellent emollient properties, emulsion stabilization, thickening capabilities, and cost-effectiveness. However, its comedogenic potential and water insolubility are important considerations for formulation design. Proper processing (melting and cooling conditions) is essential to achieve the desired texture and stability.

SECTION 18: STORAGE, SHELF LIFE AND PACKAGING

Parameter Description
Storage Temperature 15 – 30°C (cool and dry)
Storage Conditions Well-ventilated, moisture-protected area
Light Protection Normal light conditions acceptable
Moisture Sensitivity Protect from excessive moisture
Materials to Avoid Strong oxidizing agents, strong acids, strong bases
Shelf Life 24 – 36 months (unopened, recommended conditions)
Degradation Signs Color change (yellowing), odor (rancidity), acid value increase
Standard Packaging 25 kg, 50 kg PE-lined multi-layer bags or boxes
Bulk Packaging 500 kg, 1000 kg big-bags (FIBC)
Small Packaging (Upon Request) 1 kg, 5 kg, 10 kg
Packaging Material PE-lined bags, PE-lined boxes, HDPE drums (for molten form)
Closure Recommendation Keep tightly closed when not in use

Description: Myristyl Alcohol should be stored in a cool, dry place in its original packaging. It should be protected from excessive moisture to prevent caking and oxidation. Contact with strong oxidizing agents, acids, and bases should be avoided. Shelf life is 24-36 months under recommended storage conditions. Signs of degradation include yellowing, rancid odor, and increased acid value. Each package should bear the manufacturing date and batch number for traceability.

SECTION 19: TRANSPORTATION AND SHIPPING INFORMATION

Parameter Description
UN Number Not regulated (non-hazardous)
Hazard Class Not classified as dangerous goods
Packing Group Not applicable
Marine Pollutant No
Transport Classification  
ADR (Road) Not classified
RID (Rail) Not classified
ADN (Inland Waterway) Not classified
IMDG (Maritime) Not classified
IATA/ICAO (Air) Not classified
Transport Temperature Ambient temperature (15-30°C)
Transport Precautions Protect from moisture and crushing; avoid temperatures above 40°C to prevent melting
Packaging Precautions Use sturdy packaging to prevent damage; keep away from heat sources

Description: Myristyl Alcohol is not classified as dangerous goods for transportation. It does not require UN number or hazard labeling. However, proper packaging should be used to prevent physical damage and moisture ingress. Transport should be at ambient temperatures (15-30°C), and the product should be protected from excessive heat that could cause melting or deformation of packaging. The GTIP/HS code for Myristyl Alcohol is 2905.17.00.00.00.

SECTION 20: ENVIRONMENTAL INFORMATION AND ECOTOXICOLOGY

Parameter Value / Assessment
Aquatic Toxicity (Fish, LC50, 96h) > 100 mg/L (Zebra fish)
Aquatic Toxicity (Daphnia, EC50, 48h) > 100 mg/L
Algal Toxicity (EC50, 72h) > 100 mg/L
Bioaccumulation Factor (BCF) Low to moderate (due to high Log P)
Biodegradability Readily biodegradable (OECD 301F)
Biochemical Oxygen Demand (BOD5) ~0.5 – 1.0 g O₂/g
Chemical Oxygen Demand (COD) ~2.5 – 3.0 g O₂/g
Hydrolysis Not hydrolytically degradable; metabolized by microorganisms
Persistence Low (biodegradable)
Environmental Classification Slightly hazardous to the environment
Water Hazard Class (WGK, Germany) Class 1 (slightly hazardous to water)

Description: Myristyl Alcohol is readily biodegradable and does not persist in the environment. It exhibits low to moderate toxicity to aquatic organisms. Due to its high lipophilicity (Log P = 5.95), it has the potential for bioaccumulation, but its rapid biodegradation minimizes environmental persistence. It is classified as slightly hazardous to the aquatic environment. Appropriate waste management practices should be followed to minimize environmental release.

SECTION 21: QUALITY CERTIFICATES AND STANDARDS

Certificate / Standard Status Description
ISO 9001:2015 Certified Manufacturing facilities have quality management system
ISO 14001:2015 Certified Environmental management system (optional)
REACH (EC 1907/2006) Registered Compliant with EU chemical regulations
FDA 21 CFR Compliant Suitable for cosmetic and pharmaceutical applications
USP/EP Available Pharmaceutical quality standard
Halal Upon request Certified according to Islamic standards (when sourced from plant origin)
Kosher Upon request Certified according to Jewish standards
Certificate of Analysis (COA) Provided with each batch Includes binding specifications
Safety Data Sheet (SDS/MSDS) Available Current 16-section document
Technical Data Sheet (TDS) Available Comprehensive technical information
Good Manufacturing Practices (GMP) Compliant Cosmetic / Pharmaceutical GMP

SECTION 22: DISCLAIMER AND LEGAL NOTICE

Item Description
Information Purpose This Technical Data Sheet (TDS) is for informational purposes only and does not constitute a binding specification.
Typical Values Values stated herein are based on typical laboratory results and may vary slightly between production batches.
Binding Data For binding specifications, the Certificate of Analysis (COA) for each batch should be requested.
User Responsibility The user is solely responsible for determining the suitability of the product for the intended application and ensuring compliance with all applicable regulations.
SDS Requirement A current Safety Data Sheet (SDS) should be requested from the supplier prior to use.
Safety Information Safety information in this document is based on current knowledge but does not constitute a guarantee of the product's health and safety risks.
Regulatory Changes The user is responsible for monitoring local and international regulatory changes.
Product Quality Product quality is guaranteed in accordance with the standards specified in this document.
License / Patents This document does not grant any license or patent rights for use of the product.
Side Effects Allergic reactions are rare but possible in sensitive individuals; users should conduct suitability tests.

DISCLAIMER (LEGAL NOTICE): This Technical Data Sheet (TDS) is for informational purposes only and does not constitute a binding specification. The values stated herein are based on typical laboratory results. The user is solely responsible for determining the suitability of the product for the intended application and for ensuring compliance with all local regulations. A current Safety Data Sheet (SDS) and Certificate of Analysis (COA) should be requested prior to use. Allergic reactions are rare but may occur in sensitive individuals; suitability tests should be conducted. This document does not grant any license or patent rights for use of the product.

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