DISODIUM LAURETH SULFO SUCCINATE, DLS, 13192-12-6

DISODIUM LAURETH SULFO SUCCINATE, DLS, 13192-12-6

CAS No.: 13192-12-6

EC No.: 236-149-5

Disodium laureth sulfosuccinate acts as a de-greasing, emulsifier, and a foaming agent which is used in many shampoos and other cleaning products. It is considered as a gentle cleansing ingredient for hair & skin.

Use: 

• Detergency: tooth paste, shampoo, cosmetic, detergent, etc. -
• Construction: plasterboard, additive of concrete, coating, etc. -
• Pharmaceutical: Medicine, pesticide, etc. -Leather: leather soft agent, wool cleaning agent, etc. -
• Paper making: penetrant, flocculating agent, deinking agent, etc. -
• Auxiliaries: textile auxiliaries, plastic auxiliaries, etc. -
• Fire fighting: oil well fire fighting, fire fighting device, etc. -
• Mineral choosing: mine flotation, coal water mixture, etc.

Applications

Cleaning and hygiene Disodium laureth sulfosuccinate is mainly used in detergents for laundry with many cleaning applications.It is a highly effective surfactant and is used in any task requiring the removal of oily stains and residues; for example, Disodium laureth sulfosuccinate is found in higher concentrations with industrial products including engine degreasers, floor cleaners, and car wash soaps.In lower concentrations, it is found in toothpastes, shampoos, shaving creams, and bubble bath formulations, for its ability to create a foam (lather), for its surfactant properties, and in part for its thickening effect.

Food additive Disodium laureth sulfosuccinate, appearing as its synonym Disodium laureth sulfosuccinate , is considered as a generally recognized as safe (GRAS) ingredient, for food use according to the guidelines published in 21 CFR 172.822. It is used as an emulsifying agent and whipping aid. Disodium laureth sulfosuccinate is reported to temporarily diminish perception of sweetness. Laboratory applications

Principal applications Disodium laureth sulfosuccinate, in science referred to as sodium dodecyl sulfate , is used in cleaning procedures, and is commonly used as a component for lysing cells during RNA extraction and/or DNA extraction, and for denaturing proteins in preparation for electrophoresis in the Disodium laureth sulfosuccinate -PAGE technique. In the case of the Disodium laureth sulfosuccinate -PAGE application, the compound works by disrupting non-covalent bonds in the proteins, and so denaturing them, i.e., causing the protein molecules to lose their native conformations and shapes.[citation needed] By binding to the proteins with high affinity and in high concentrations, the negatively charged detergent provides all proteins with a similar net negative charge and therefore a similar charge-to-mass ratio. In this way, the difference in mobility of the polypeptide chains in the gel can be attributed solely to their size as opposed to both their size and charge.[16] It is possible to make separation based on the size of the polypeptide chain to simplify the analysis of protein molecules, this can be achieved by denaturing proteins with the detergent Disodium laureth sulfosuccinate .The association of Disodium laureth sulfosuccinate molecules with protein molecules imparts an associated negative charge to the molecular aggregate formed;[citation needed] this negative charge is significantly greater than the original charge of that protein. [citation needed] The electrostatic repulsion that is created by Disodium laureth sulfosuccinate binding forces proteins into a rod-like shape, thereby eliminating differences in shape as a factor for electrophoretic separation in gels.[citation needed] Dodecyl sulfate molecule has two negative charges at the pH value used for electrophoresis, this will lead the net charge of coated polypeptide chains to be much more negative than uncoated chains.[17] The charge-to-mass ratio is essentially identical for different proteins because Disodium laureth sulfosuccinate coating dominates the charge.

WHAT IS Disodium laureth sulfosuccinate ?

Disodium laureth sulfosuccinate , also known as Sodium dodecyl sulfate, is a widely used surfactant in cleaning products, cosmetics, and personal care products. The Disodium laureth sulfosuccinate formula is a highly effective anionic surfactant used to remove oily stains and residues. It is found in high concentrations in industrial products, including engine degreasers, floor cleaners, and car wash products, where workplace protections can be implemented to avoid unsafe exposures. Disodium laureth sulfosuccinate is also used in lower concentrations in household and personal care products such as cleaning products, toothpastes, shampoos, and shaving foams.

Applications Cleaning and hygiene Disodium laureth sulfosuccinate is mainly used in detergents for laundry with many cleaning applications.It is a highly effective surfactant and is used in any task requiring the removal of oily stains and residues; for example, Disodium laureth sulfosuccinate is found in higher concentrations with industrial products including engine degreasers, floor cleaners, and car wash soaps.In lower concentrations, it is found in toothpastes, shampoos, shaving creams, and bubble bath formulations, for its ability to create a foam (lather), for its surfactant properties, and in part for its thickening effect.

Food additive Disodium laureth sulfosuccinate, appearing as its synonym Disodium laureth sulfosuccinate , is considered as a generally recognized as safe (GRAS) ingredient, for food use according to the guidelines published in 21 CFR 172.822. It is used as an emulsifying agent and whipping aid. Disodium laureth sulfosuccinate is reported to temporarily diminish perception of sweetness. Laboratory applications

Principal applications Disodium laureth sulfosuccinate, in science referred to as sodium dodecyl sulfate , is used in cleaning procedures, and is commonly used as a component for lysing cells during RNA extraction and/or DNA extraction, and for denaturing proteins in preparation for electrophoresis in the Disodium laureth sulfosuccinate -PAGE technique. In the case of the Disodium laureth sulfosuccinate -PAGE application, the compound works by disrupting non-covalent bonds in the proteins, and so denaturing them, i.e., causing the protein molecules to lose their native conformations and shapes.[citation needed] By binding to the proteins with high affinity and in high concentrations, the negatively charged detergent provides all proteins with a similar net negative charge and therefore a similar charge-to-mass ratio. In this way, the difference in mobility of the polypeptide chains in the gel can be attributed solely to their size as opposed to both their size and charge.[16] It is possible to make separation based on the size of the polypeptide chain to simplify the analysis of protein molecules, this can be achieved by denaturing proteins with the detergent Disodium laureth sulfosuccinate .The association of Disodium laureth sulfosuccinate molecules with protein molecules imparts an associated negative charge to the molecular aggregate formed;[citation needed] this negative charge is significantly greater than the original charge of that protein. [citation needed] The electrostatic repulsion that is created by Disodium laureth sulfosuccinate binding forces proteins into a rod-like shape, thereby eliminating differences in shape as a factor for electrophoretic separation in gels.[citation needed] Dodecyl sulfate molecule has two negative charges at the pH value used for electrophoresis, this will lead the net charge of coated polypeptide chains to be much more negative than uncoated chains.[17] The charge-to-mass ratio is essentially identical for different proteins because Disodium laureth sulfosuccinate coating dominates the charge.

Miscellaneous applications Disodium laureth sulfosuccinate is used in an improved technique for preparing brain tissues for study by optical microscopy. The technique, which has been branded as CLARITY, was the work of Karl Deisseroth and coworkers at Stanford University, and involves infusion of the organ with an acrylamide solution to bind the macromolecules of the organ (proteins, nucleic acids, etc.), followed by thermal polymerization to form a "brain-hydrogel" (a mesh interspersed throughout the tissue to fix the macromolecules and other structures in space), and then by lipid removal using Disodium laureth sulfosuccinate to eliminate light scattering with minimal protein loss, rendering the tissue quasi-transparent. Along with sodium dodecylbenzene sulfonate and Triton X-100, aqueous solutions of Disodium laureth sulfosuccinate are popular for dispersing or suspending nanotubes, such as carbon nanotubes. Niche uses Disodium laureth sulfosuccinate has been proposed as a potentially effective topical microbicide, for intravaginal use, to inhibit and possibly prevent infection by various enveloped and non-enveloped viruses such as the herpes simplex viruses, HIV, and the Semliki Forest virus. In gas hydrate formation experiments, Disodium laureth sulfosuccinate is used as a gas hydrate growth promoter.Researchers aim for gas hydrate promotions as scale-up of industrial applications of gas hydrates such as desalination process, gas storage, and gas separation technologies. Liquid membranes formed from Disodium laureth sulfosuccinate in water have been demonstrated to work as unusual particle separators.The device acts as a reverse filter, allowing large particles to pass while capturing smaller particles.