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Send EmailName | Tris(2-hydroxypropyl)amine |
Synonyms | AMIX TI NITRILOTRIPROPANOL TRIISOPROPANOLAMINE (Mixture of isoMer) TRIS(2-HYDROXYPROPYL)AMINE Tris(2-hydroxypropyl)amine 1,1',1''-NITRILOTRIPROPAN-2-OL 1,1',1''-NITRILOTRI-2-PROPANOL 1,1',1''-NITROLOTRIPROPAN-2-OL 1,1',1''-NITRILOTRIS(2-PROPANOL) 2-Propanol, 1,1',1''-nitrilotri- TriisopropanolaMine, Mixture of isoMers (2S,2'S,2''R)-1,1',1''-nitrilotripropan-2-ol 2-hydroxy-N,N-bis(2-hydroxypropyl)propan-1-aminium chloride (2S)-2-hydroxy-N,N-bis[(2R)-2-hydroxypropyl]propan-1-aminium (2R)-2-hydroxy-N,N-bis[(2R)-2-hydroxypropyl]propan-1-aminium (2S)-2-hydroxy-N-[(2R)-2-hydroxypropyl]-N-[(2S)-2-hydroxypropyl]propan-1-aminium |
CAS | 122-20-3 |
EINECS | 204-528-4 |
InChI | InChI=1/C9H21NO3/c1-7(11)4-10(5-8(2)12)6-9(3)13/h7-9,11-13H,4-6H2,1-3H3/p+1/t7-,8-,9-/m1/s1 |
Molecular Formula | C9H21NO3 |
Molar Mass | 191.27 |
Density | 1.0 |
Melting Point | 48-52 °C (lit.) |
Boling Point | 190 °C/23 mmHg (lit.) |
Flash Point | 160 °C |
Water Solubility | Soluble |
Solubility | Soluble in water (>1000 mg/ml at 25 °C), ethanol, diethyl ether, chloroform (slightly) |
Vapor Presure | 1 hPa (100 °C) |
Appearance | Pale yellow crystal |
Color | White to slightly yellow |
BRN | 1071570 |
pKa | 14.37±0.20(Predicted) |
PH | 10.8 (100g/l, H2O, 20℃) |
Storage Condition | Store below +30°C. |
Sensitive | Hygroscopic |
Explosive Limit | 0.8-5.8%(V) |
Refractive Index | 1.4200 (estimate) |
MDL | MFCD00004533 |
Physical and Chemical Properties | White crystalline solid, weakly alkaline. |
Use | It is mainly used in the synthesis of intermediates, as well as as as a chain extender on PU and as a neutralizing agent on daily chemicals. |
Hazard Symbols | Xi - Irritant |
Risk Codes | R36 - Irritating to the eyes R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN 3259 8/PG 2 |
WGK Germany | 1 |
RTECS | UB8750000 |
TSCA | Yes |
HS Code | 2922 19 00 |
Hazard Class | 8 |
Packing Group | III |
Toxicity | LD50 orally in Rabbit: 4000 mg/kg LD50 dermal Rabbit 10000 mg/kg |
Soluble in water, soluble in ethanol and ether.
freezing point | 52 ℃ |
LogP | -0.015 at 23℃ |
use | used as pharmaceutical raw materials, solvent for photo developer, solvent for paraffin oil in man-made fibers, emulsifier for cosmetics, etc. triisopropanolamine can be used as gas absorbent and antioxidant; Cement industry is used as grinding aid; Fiber industry is used as refining agent, antistatic agent, dyeing aid and fiber wetting agent; Used as antioxidant and plasticizer in lubricating oil and cutting oil; the plastic industry is used as a crosslinking agent; it can also be used as a dispersant for titanium dioxide, minerals, and a curing agent in the polyurethane industry. It is mainly used for the synthesis of intermediates, as a chain extender on PU and as a neutralizing agent on daily chemicals. |
production method | liquid ammonia and propylene oxide are used as raw materials, water is used as catalyst, materials are prepared according to the molar ratio of liquid ammonia to propylene oxide of 1: 3.00~3.05, deionized water is added at one time, and the dosage ensures that the concentration of ammonia water is 28 ~ 60%; Liquid ammonia and propylene oxide are divided into secondary feeding, and half of the amount of liquid ammonia is added first each time, keep the temperature at 20~50 ℃, then slowly add half of the amount of propylene oxide, fully stir, and keep the pressure in the kettle below 0.5MPa, the reaction temperature is 20~75 ℃, and maintain for 1.0~3.0 hours; After adding propylene oxide, control the temperature of the reaction kettle to 20~120 ℃, make it continue to react for 1.0~3.0 hours, dehydrate under reduced pressure until the water content is less than 5%, and obtain triisopropanolamine product. The method can effectively produce one isopropanolamine and diisopropanolamine, the process is simple, the investment cost is low. |
spontaneous combustion temperature | 275°C |
A Low Freeze Grade blend of Triisopropanolamine and 15% water to lower the freezing point for easier handling. A basic chemical used in many applications serving as an emulsifier, stabilizer, chemical intermediate and neutralizer that achieves basicity, buffering and alkalinity objectives.
TIPA is an effective emulsifier, stabilizer, neutralizer, and chemical intermediate for achieving the objectives of alkalinity, basicity