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Acetic Acid, Ethanoic Acid, Vinegar Acid, Ethanoic Acid, Methane Carboxylic Acid, E260, 64-19-7

Acetic Acid, Ethanoic Acid, Vinegar Acid, Ethanoic Acid, Methane Carboxylic Acid, E260, 64-19-7

ACETIC ACID (CH₃COOH - E260)

PRODUCT IDENTIFICATION INFORMATION

Parameter Information
Product Name Acetic Acid
Chemical Name Acetic Acid (Ethanoic Acid)
Synonyms (Turkish) Asetik Asit, Etanoik Asit, Sirke Asidi, Sirke Ruhu
Synonyms (English) Acetic Acid, Ethanoic Acid, Methanecarboxylic Acid, Vinegar Acid, Glacial Acetic Acid, Ethylic Acid, Pyroligneous Acid
E Number E260
CAS Number 64-19-7
EC Number 200-580-7
Molecular Formula CH₃COOH (C₂H₄O₂)
Molecular Weight 60.05 g/mol
Appearance Colorless liquid
Odor Sharp, pungent, vinegar-like odor

CHEMICAL STRUCTURE

Acetic Acid Structure:

        O
        ||
    CH₃—C—OH

Structure Description:

  • Simple carboxylic acid (organic acid).

  • Contains a carboxyl group (-COOH) attached to a methyl group (-CH₃).

  • Colorless liquid with a sharp, pungent odor.

  • Weak acid (pKa = 4.76).

  • Miscible with water in all proportions.

  • Corrosive and flammable.

SECTION 1: CHEMICAL IDENTITY AND DESCRIPTION

Parameter Information
Product Name Acetic Acid
Chemical Name Acetic Acid (Ethanoic Acid)
Synonyms (Turkish) Asetik Asit, Etanoik Asit, Sirke Asidi, Sirke Ruhu
Synonyms (English) Acetic Acid, Ethanoic Acid, Methanecarboxylic Acid, Vinegar Acid, Glacial Acetic Acid, Ethylic Acid, Pyroligneous Acid
E Number E260
CAS Number 64-19-7
EC Number 200-580-7
Molecular Formula CH₃COOH (C₂H₄O₂)
Molecular Weight 60.05 g/mol
Chemical Class Carboxylic acid; Organic acid; Food additive
Source Synthetic (methanol carbonylation) or natural (fermentation)
Physical State (20°C) Liquid
Odor Sharp, pungent, vinegar-like odor
Color Colorless
Taste Sour, acidic

SECTION 2: PHYSICAL AND CHEMICAL PROPERTIES

Property Value Test Method / Note
Appearance Colorless liquid Visual
Odor Sharp, pungent, vinegar-like Olfactometric
Molecular Weight 60.05 g/mol Calculated
Density (20°C) 1.049 g/cm³ ASTM D4052
Melting Point 16 – 17°C DSC
Boiling Point 118 – 119°C
Flash Point 37°C (closed cup)
Autoignition Temperature 463°C
Explosive Limits 4.0 – 19.9% (v/v in air)
Vapor Pressure (20°C) ~15 mmHg
Vapor Density (Air=1) 2.07
Solubility in Water Miscible (in all proportions) General Method
Solubility in Ethanol Miscible General Method
Solubility in Ether Miscible General Method
Solubility in Organic Solvents Miscible General Method
pH (1% Solution) ~2.4 (acidic) pH Meter
pKa 4.76
Stability Stable under normal conditions
Hygroscopicity Moderate
Corrosivity Corrosive to metals and tissues
Heavy Metals (as Pb) ≤ 10 ppm AAS / ICP
Arsenic (As) ≤ 2 ppm AAS / ICP
Lead (Pb) ≤ 2 ppm AAS / ICP
Chloride (Cl) ≤ 0.01% Titrimetric
Sulfate (SO₄) ≤ 0.01% Gravimetric
Residue on Evaporation ≤ 0.05% Gravimetric
Assay (CH₃COOH) ≥ 99.5% (glacial); 80% (technical) Titrimetric

SECTION 3: ACETIC ACID vs OTHER ORGANIC ACIDS

Property Acetic Acid (C2) Citric Acid (C6) Formic Acid (C1) Lactic Acid (C3)
CAS Number 64-19-7 77-92-9 64-18-6 50-21-5
Molecular Weight 60.05 g/mol 192.12 g/mol 46.03 g/mol 90.08 g/mol
pKa 4.76 3.13 3.75 3.86
Boiling Point 118-119°C 310°C (decomp.) 100.8°C 122°C
Density (20°C) 1.049 g/cm³ 1.665 g/cm³ 1.220 g/cm³ 1.206 g/cm³
Odor Vinegar-like Odorless Pungent Odorless
Flash Point 37°C 190°C 69°C 110°C
Primary Use Food additive, chemical intermediate Food acidulant Preservative, leather Food, cosmetics
E Code E260 E330 E236 E270

SECTION 4: MECHANISM OF ACTION

Property Description
Acidity Weak acid; Dissociates in water to form acetate (CH₃COO⁻) and hydrogen (H⁺) ions; Acts as a pH regulator; Provides acidic taste and preservation.
Preservation Lowers pH of food products; Inhibits bacterial growth; Creates an environment unfavorable for spoilage organisms; Effective against many bacteria and fungi.
Chemical Reactions Reacts with bases to form acetates (salts); Reacts with alcohols to form esters (flavors and fragrances); Reacts with metals (corrosive); Used in esterification reactions.
Solvent Dissolves many organic compounds; Used in chemical processes; Acts as a solvent for resins, dyes, and polymers.
Metabolism In the body, acetate is metabolized to CO₂ and H₂O; Used in the citric acid cycle as a carbon source; Converted to acetyl-CoA.
Disinfection Antimicrobial properties at high concentrations; Used as a disinfectant and sanitizer; Effective against bacteria and fungi.

SECTION 5: PRODUCTION PROCESS

Industrial Production Methods:

Method 1: Methanol Carbonylation (Monsanto Process)

Reaction: CH₃OH + CO → CH₃COOH

Description: Methanol and carbon monoxide are reacted in the presence of a rhodium or iridium catalyst and iodine promoter. The reaction is carried out at 150-200°C and 30-60 atm. The product is purified by distillation.

Method 2: Oxidation of Acetaldehyde

Reaction: 2CH₃CHO + O₂ → 2CH₃COOH

Description: Acetaldehyde is oxidized with air or oxygen in the presence of a catalyst (manganese acetate, cobalt acetate). The product is purified by distillation.

Method 3: Natural Fermentation

Process: Ethanol + O₂ → Acetic Acid + H₂O

Description: Ethanol is oxidized by acetic acid bacteria (Acetobacter) in aerobic fermentation. Used for vinegar production (typically 4-8% acetic acid).

SECTION 6: FUNCTIONAL PROPERTIES

Property Description
Acidulant (pH Regulator) Provides acidic taste; Adjusts and controls pH in food products; Acts as a buffering agent; Enhances flavor profiles.
Preservative Lowers pH to inhibit microbial growth; Extends shelf life of food products; Prevents spoilage; Used in pickling and sauces.
Chemical Intermediate Precursor for many industrial chemicals; Vinyl acetate production; Acetic anhydride production; Cellulose acetate production; Metal acetate production.
Solvent Dissolves resins, dyes, and polymers; Used in coatings, inks, and adhesives; Acts as a reaction solvent.
Flavoring Agent Provides sour taste (vinegar); Used in food products (sauces, dressings, pickles); Enhances overall flavor.
Disinfectant/Sanitizer Antimicrobial properties; Used in cleaning and sanitizing; Effective against bacteria and fungi.

SECTION 7: MAIN APPLICATION AREAS

Industry / Application Function Typical Use
Food Industry (E260) Acidulant, preservative, flavoring agent Vinegar production (4-8%); Pickling; Salad dressings, sauces, ketchup, mayonnaise; Bakery products (dough conditioner); Food preservative; pH regulator; Dosage: 0.5-5% depending on product.
Chemical Industry Chemical intermediate, solvent Vinyl acetate production (paints, adhesives); Acetic anhydride production (pharmaceuticals); Cellulose acetate production (fibers, plastics); Metal acetates production; Solvent for organic reactions.
Plastics & Fibers Monomer precursor, solvent Polyvinyl acetate (PVA) production; Cellulose acetate (textile fibers, films); Plasticizers; Synthetic fibers.
Pharmaceutical Solvent, intermediate, reagent Drug synthesis (aspirin, paracetamol); Solvent for crystallization; Laboratory reagent; Antimicrobial solutions.
Cleaning Products Descaler, degreaser Household and industrial cleaners; Scale and stain removers; Glass cleaners; Surface disinfectants.
Textile & Leather Dyeing aid, tanning agent Textile dyeing and finishing; Leather tanning; Bleaching and treatment of leather.
Agriculture Herbicide, fungicide Agricultural chemicals (herbicides, fungicides); Plant protection products; Acidifying agent for irrigation water.
Paper & Printing Solvent, pH adjuster Printing inks; Paper coating; Pulp bleaching aid.
Cosmetics pH adjuster, preservative Skin care products; Hair care products; pH adjustment; Preservative for formulations.

SECTION 8: SAMPLE FORMULATIONS

Food Grade Dilution (5% Vinegar):

Component Amount
Acetic Acid (Glacial 99.5%) 5 mL
Water (Purified) To 100 mL

Instructions: Carefully add acetic acid to water with stirring; Use for food applications; Store in appropriate containers.

Descaling Solution (10% Acetic Acid):

Component Amount
Acetic Acid (Glacial 99.5%) 10 mL
Water To 100 mL

Instructions: Dilute acetic acid with water; Use for scale and limescale removal; Rinse surfaces thoroughly after use.

SECTION 9: QUALITY SPECIFICATIONS

Parameter Food Grade (E260) Technical Grade Pharmaceutical Grade Test Method
Appearance Colorless liquid Colorless liquid Colorless liquid Visual
Assay (CH₃COOH) ≥ 99.5% ≥ 99.0% ≥ 99.8% Titrimetric
Density (20°C) 1.049 – 1.051 g/cm³ 1.049 – 1.051 g/cm³ 1.049 – 1.051 g/cm³ ASTM D4052
Melting Point 16.2 – 16.7°C 16.0 – 16.7°C 16.2 – 16.7°C DSC
Residue on Evaporation ≤ 0.01% ≤ 0.05% ≤ 0.005% Gravimetric
Heavy Metals (as Pb) ≤ 5 ppm ≤ 10 ppm ≤ 5 ppm AAS / ICP
Arsenic (As) ≤ 1 ppm ≤ 1 ppm AAS / ICP
Lead (Pb) ≤ 1 ppm ≤ 1 ppm AAS / ICP
Chloride (Cl) ≤ 0.001% ≤ 0.01% ≤ 0.001% Titrimetric
Sulfate (SO₄) ≤ 0.001% ≤ 0.01% ≤ 0.001% Gravimetric
Formic Acid ≤ 0.05% ≤ 0.1% ≤ 0.05% HPLC

SECTION 10: TOXICOLOGICAL PROFILE

Parameter Value
Acute Oral Toxicity (LD50, Rat) ~ 3,300 mg/kg (moderate toxicity)
Acute Dermal Toxicity Low toxicity; May cause mild irritation
Skin Irritation Corrosive; Causes severe burns (H314)
Eye Irritation Severe; Causes serious eye damage (H318)
Inhalation Toxicity May cause respiratory irritation (H335); Vapors are irritating
Chronic Toxicity May cause skin sensitization; Repeated exposure may cause dermatitis
Carcinogenicity Not classified as carcinogenic
Mutagenicity Not mutagenic
Reproductive Toxicity No reproductive toxicity at normal levels
Environmental Toxicity Low toxicity; Biodegradable; Harmful to aquatic life at high concentrations
Special Toxicity Note Corrosive; Causes severe skin burns and eye damage (H314); Harmful if swallowed (H302); May cause respiratory irritation (H335); Vapors can cause eye and respiratory irritation; Use appropriate PPE; Avoid contact with skin and eyes.

SECTION 11: GHS CLASSIFICATION AND LABELING

GHS Classification (in accordance with CLP and UN GHS):

Hazard Class Category H-Statement
Flammable Liquids Category 3 H226
Acute Toxicity (Oral) Category 4 H302
Skin Corrosion/Irritation Category 1A H314
Serious Eye Damage Category 1 H318
Specific Target Organ Toxicity (Single) Category 3 H335

Signal Word: DANGER

Hazard Pictograms: GHS02 (Flame), GHS05 (Corrosive), GHS07 (Exclamation Mark)

Hazard Statements (H-Codes):

Code Statement
H226 Flammable liquid and vapor
H302 Harmful if swallowed
H314 Causes severe skin burns and eye damage
H318 Causes serious eye damage
H335 May cause respiratory irritation

NFPA 704 Hazard Classification:

Health Flammability Reactivity Special
3 2 0 -
(Severe health hazard - corrosive) (Moderate fire hazard) (Stable) (None)

SECTION 12: PRECAUTIONARY STATEMENTS (P-CODES)

Code Statement
P210 Keep away from heat/sparks/open flames/hot surfaces — No smoking
P233 Keep container tightly closed
P240 Ground/bond container and receiving equipment
P241 Use explosion-proof electrical/ventilating/lighting equipment
P242 Use only non-sparking tools
P243 Take precautionary measures against static discharge
P260 Do not breathe dust/fume/gas/mist/vapors/spray
P264 Wash hands thoroughly after handling
P280 Wear protective gloves/protective clothing/eye protection/face protection
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and continue rinsing
P310 Immediately call a POISON CENTER/doctor
P363 Wash contaminated clothing before reuse
P403+P233 Store in a well-ventilated place. Keep container tightly closed
P501 Dispose of contents/container in accordance with local/regional/national/international regulations

SECTION 13: FIRST AID MEASURES

Exposure Route Action to Take
Inhalation Remove to fresh air immediately. If respiratory irritation develops, seek medical attention.
Skin Contact Immediately remove contaminated clothing. Rinse with plenty of water for at least 15 minutes. Get immediate medical attention.
Eye Contact Immediately rinse with plenty of water for at least 15 minutes. Keep eyelids open. Remove contact lenses if present. Get immediate medical attention.
Ingestion DO NOT INDUCE VOMITING. Rinse mouth. Drink plenty of water (only if conscious). Get immediate medical attention.

SECTION 14: FIREFIGHTING MEASURES

Parameter Information
Fire Hazard Flammable liquid. Vapors may form explosive mixtures with air.
Hazards Arising from Fire Thermal decomposition produces carbon monoxide, carbon dioxide, and irritating fumes.
Suitable Extinguishing Media Water spray, CO₂, dry chemical powder, foam (alcohol-resistant).
Unsuitable Extinguishing Media Water jet (may spread burning liquid)
Special Protective Equipment Self-contained breathing apparatus (SCBA), full protective clothing, firefighting goggles.
Special Precautions Evacuate area; Prevent fire-fighting water from entering waterways; Cool fire-exposed containers with water spray; Stop leak if safe.

SECTION 15: STORAGE AND SHELF LIFE

Parameter Information
Storage Conditions Store in a cool, dry, well-ventilated area; PROTECT FROM LIGHT, HEAT, and MOISTURE; Keep away from direct sunlight and high temperatures.
Container Requirements Tightly closed containers (HDPE, stainless steel, glass, coated drums).
Materials to Protect From Heat, moisture, oxidizing agents, bases, metals
Shelf Life 24 – 48 months (in unopened original packaging, under proper storage conditions).
Stability Note Stable under recommended storage conditions; Can freeze at low temperatures; May corrode metals; Protect from moisture.
Special Storage Requirements Store in a cool, dry, well-ventilated area; Avoid exposure to air and moisture; Opened containers must be resealed immediately; Keep away from sources of ignition.

SECTION 16: PACKAGING OPTIONS

Packaging Type Quantity Material
HDPE Canister 5 L, 10 L, 20 L HDPE (chemical-resistant)
HDPE Drum 25 kg, 50 kg, 60 kg HDPE (sealed, chemical-resistant)
Stainless Steel Drum 50 kg, 100 kg, 200 kg Stainless steel (304/316)
IBC Container 500 L, 1000 L HDPE or stainless steel IBC (returnable/non-returnable)
Tank Container 10,000 – 25,000 L Stainless steel (316L) – bulk transport
Glass Bottle 1 L, 2.5 L, 5 L Amber glass (light protection)

SECTION 17: TRANSPORT INFORMATION

Parameter Information
UN Number UN 2789 (Acetic Acid, Glacial) / UN 2790 (Acetic Acid, solution <80%)
Hazard Class Class 8 - Corrosive Substances / Class 3 - Flammable (Glacial)
Packing Group II
ADR/RID Class 8; UN 2789/2790; Packing Group II
IMDG Code Class 8; UN 2789/2790; Marine pollutant: No
IATA (Air) Class 8; UN 2789/2790; Packing Group II
Transport Label Corrosive, Flammable
Marine Pollutant No
Special Transport Requirements Segregation from oxidizing agents, bases, and combustibles; Protect from moisture; Secure from unauthorized access.

SECTION 18: REGULATORY STATUS

Region / Authority Status
European Union Food additive E260 approved by EFSA; REACH registered; Approved for food, pharmaceutical, and industrial use.
USA (TSCA) Listed (TSCA Inventory)
USA (FDA) GRAS (Generally Recognized as Safe) ; 21 CFR 184.1005; Approved for food use.
Turkey Food additive E260; Ministry of Agriculture approval required; KKDIK regulation compliance required; Approved for food and industrial use.
EFSA Approved; No ADI specified (safe).
JECFA Approved; No ADI specified (safe); Specifications included.
IARC Not classified (non-carcinogenic)
NTP Not listed
OSHA Regulated as corrosive and flammable; PEL: 10 ppm (TWA).
California (Prop 65) Not listed
Halal Yes (with certification)
Kosher Yes (with certification)
Vegan Yes (synthetic, non-animal source)

SECTION 19: OTHER NAMES AND SYNONYMS

Type Name
Turkish Names Asetik Asit, Etanoik Asit, Sirke Asidi, Sirke Ruhu
English Names Acetic Acid, Ethanoic Acid, Methanecarboxylic Acid, Vinegar Acid, Glacial Acetic Acid, Ethylic Acid, Pyroligneous Acid
E Number E260
CAS Number 64-19-7
EC Number 200-580-7
HS Code 2915.21

SECTION 20: SUMMARY TABLE

Parameter Value
Product Acetic Acid (E260)
CAS Number 64-19-7
E Number E260
Molecular Formula CH₃COOH (C₂H₄O₂)
Molecular Weight 60.05 g/mol
Appearance Colorless liquid
Odor Sharp, pungent, vinegar-like
Density (20°C) 1.049 g/cm³
Melting Point 16-17°C
Boiling Point 118-119°C
Flash Point 37°C
Solubility Miscible with water, ethanol, ether
Primary Functions Acidulant, preservative, solvent, chemical intermediate
Main Application Areas Food (E260), chemical, plastics, pharmaceuticals, cleaning, textiles, agriculture
Shelf Life 24 – 48 months
GHS Signal Word DANGER
UN Number 2789 (Glacial) / 2790 (Solution)
Hazard Class Class 8 (Corrosive) / Class 3 (Flammable)
Packing Group II
Special Properties Corrosive; Flammable; Weak acid; Miscible with water; GRAS; FDA approved; Vegan; Halal; Versatile.

SECTION 21: CRITICAL WARNINGS AND BEST PRACTICES

CRITICAL WARNINGS:

  • CORROSIVE (H314, H318): Causes severe skin burns and eye damage. PERSONAL PROTECTIVE EQUIPMENT IS MANDATORY.

  • FLAMMABLE LIQUID (H226): Flammable liquid and vapor. KEEP AWAY FROM SOURCES OF IGNITION.

  • HARMFUL IF SWALLOWED (H302): Avoid ingestion; Use appropriate safety measures.

  • MAY CAUSE RESPIRATORY IRRITATION (H335): Avoid inhalation of vapors.

  • FREEZES AT LOW TEMPERATURES: Melting point 16-17°C; May solidify in cold environments; Warm gently (do not apply direct heat).

  • CORROSIVE TO METALS: Reacts with many metals (Fe, Al, Zn) to produce hydrogen gas; Use appropriate materials (HDPE, stainless steel, glass).

  • REACTS WITH OXIDIZING AGENTS: Fire and explosion hazard; DO NOT MIX WITH OXIDIZERS.

  • REACTS WITH BASES: Exothermic neutralization; Use caution.

  • MISCIBLE WITH WATER: Dilution is exothermic (heat release); Always add acid to water (not water to acid).

  • GRAS Status: FDA GRAS (21 CFR 184.1005); EFSA approved; Safe for food use.

BEST PRACTICE RECOMMENDATIONS:

  • Food Industry: Use as acidulant and preservative; Vinegar production, pickling, sauces, dressings; Dosage: 0.5-5% depending on product; Dilute with water before use; Food-grade material required.

  • Chemical Industry: Use as intermediate and solvent; Vinyl acetate, acetic anhydride, cellulose acetate production; Chemical synthesis; Use in appropriate reactors; Follow safety protocols for handling corrosive and flammable liquids.

  • Cleaning Products: Use as descaler and degreaser; Household and industrial cleaners; Dilute to 5-10% for descaling; Rinse surfaces thoroughly.

  • Handling: Use in well-ventilated areas; Avoid inhalation of vapors; Use explosion-proof equipment; Grounding and bonding required; Avoid static discharge; Use closed systems; Always add acid to water (never water to acid).

  • Personal Protective Equipment: MANDATORY: Chemical-resistant gloves (nitrile, neoprene, butyl), safety goggles or face shield, protective clothing (PVC or neoprene), chemical-resistant apron, vapor/gas respirator (organic vapor cartridge), fire-retardant clothing.

  • Hygiene: Wash hands thoroughly after handling; Do not eat, drink, or smoke while using; Remove contaminated clothing and wash before reuse.

  • Storage: Store in tightly closed, corrosion-resistant containers; Store in cool, dry, well-ventilated area; Protect from heat and sources of ignition; Keep away from oxidizing agents and bases; Prevent freezing (if possible); Opened containers must be resealed immediately; Shelf life: 24-48 months under proper conditions.

  • Spill Management: Eliminate all ignition sources; Use spark-proof equipment; Neutralize with soda ash or lime; Absorb with inert material (sand, vermiculite); Collect in suitable sealed container; Do not allow entry into drains or waterways.

  • Disposal: Dispose of in accordance with local, regional, and national regulations; Hazardous waste (corrosive, flammable); Neutralize before disposal; Use authorized disposal facilities.

DETECTION METHODS:

Method Description Advantages Disadvantages
Titrimetric (Acid-Base) Neutralization with NaOH Simple, accurate, standard method Requires indicator
GC (Gas Chromatography) Quantitative analysis High sensitivity, accurate High cost, requires expertise
HPLC High-performance liquid chromatography High sensitivity, specific High cost, requires expertise
FTIR Functional group identification Fast, non-destructive Requires reference spectra
Refractometry Refractive index measurement Simple, rapid Not specific
Density Measurement Specific gravity Simple, rapid Not specific

ACETIC ACID vs ALTERNATIVES COMPARISON:

Product Chemical Name / E Code Application Strength Weakness Status
Acetic Acid (E260) CH₃COOH Food, chemical, cleaning Versatile, cheap, GRAS, effective Corrosive, flammable, pungent odor Widely approved
Citric Acid (E330) C₆H₈O₇ Food, beverages Safe, natural, non-corrosive More expensive, lower acidity Widely approved
Lactic Acid (E270) C₃H₆O₃ Food, cosmetics Mild, natural More expensive, weaker acid Widely approved
Phosphoric Acid (E338) H₃PO₄ Food, fertilizers Strong acid, cheap Corrosive, environmental concerns Widely approved
Hydrochloric Acid HCl Industrial, cleaning Very strong acid, cheap Highly corrosive, toxic Widely used

LEGAL DISCLAIMER:
The information provided in this document is based on our current knowledge and experience and is presented in good faith. However, as all conditions of use are beyond our control, it does not constitute a binding specification or warranty. This Technical Data Sheet is for informational purposes only. Users are responsible for testing the suitability for their own applications and for complying with all local, regional, and national regulations. For complete safety, storage, use, handling, waste, and regulatory compliance information, please refer to the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier. Acetic acid is a corrosive and flammable substance; strict safety protocols must be followed at all times.

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