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Chloroacetic Acid, Monochloroacetic Acid, Mono Chloro Acetic Acid, Chloro Acetate, Chloro Acetic Acid, 79-11-8

Chloroacetic Acid, Monochloroacetic Acid, Mono Chloro Acetic Acid, Chloro Acetate, Chloro Acetic Acid, 79-11-8

 

Monochloroacetic acid, MCA, or Sodium monochloroacetate is a versatile compound with the chemical formula C2HCl3O2. MCA is an essential ingredient used in various industrial applications. It is a colorless and odorless white crystalline powder used extensively in chemical synthesis. We offer this versatile compound in granules, powder, crystals, and flakes. It is a vital component in the synthesis of carboxymethylcellulose. We provide this versatile compound with exceptional purity (99.5%) for optimal performance and consistency. Opt for the most trusted suppliers of monochloroacetic acid for an excellent MCA that meets industrial needs with reliability and precision. With its precise chemical composition, our MCA serves as an essential ingredient in pharmaceuticals, herbicides, textiles, food processing, and dyes.

Our range of MCA exhibits unique properties, making it ideal for various industries seeking reliable and efficient chemical solutions. It has the ability to adjust pH levels and serve as a preservative in multiple personal care products like shampoos, cosmetics, and soaps. We have a proven track record of delivering high-quality MCA across the globe. With extensive production capacity, we ensure a consistent supply of monochloroacetic acid to meet your requirements.

Key Features of Monochloroacetic Acid

  • It is soluble in water and most solvents, making it perfect to be used as a raw material in various industries.
  • It reacts readily with bases, alcohol, and different organic compounds.
  • Its versatility and reactivity make it essential for synthesizing pharmaceutical and organic chemicals.
  • Its high purity allows efficient integration in other applications.

Applications of Monochloroacetic Acid

Stellar Exports ensures purity and adheres to required standards and regulations for safe production and handling. We comply with the industry's set safety protocols and regulations to maximize its potential application across different sectors. As prominent Monochloroacetic acid sellers, we prioritize quality and purity to provide customers with a reliable and versatile compound for their specific requirements. The primary application of Monochloroacetic acid is in the production of carboxymethyl cellulose (CMC), a vital component in manufacturing synthetic textile fibers, food additives, and pharmaceuticals. Other applications include:

  • Agricultural sector

    It is a critical ingredient in herbicides and pesticides. Its exceptional herbicidal properties prevent weed growth and promote sustainable agricultural practices.

  • Pharmaceutical

    Monochloroacetic acid is employed as the synthesis of drugs used to treat hypertension, infectious diseases, and others. It plays a pivotal role in drug formulation.

  • Chemical & textile

    The Monochloroacetic Acid manufacturers serve the chemical textile industries. It exhibits unique properties to modify polymers and works as raw material in the production of resins, dyes, and thickeners.

  • Personal care products

    They are used to produce facial cleaners, skin creams, and hair care products. It serves as a preservative, pH adjuster, and anti-microbial agent.

 

Why choose the leading Monochloroacetic Acid exporters?

Stellar Exports strives to provide the finest monochloroacetic acid for all your applications. Our global networks have enabled us to serve customers worldwide and deliver top-notch products. By choosing Stellar Exports, you are assured of top-quality chemicals, exceptional service, and technical support.

  • Extensive Experience

    We have years of experience in the production of monochloroacetic acid. This expertise and in-depth industry knowledge allow us to understand the intricacies of the manufacturing process, resulting in consistent, reliable, and high-quality products.

  • Application-Specific Solutions

    We understand that every industry is different, and so are their requirements. Hence, we customize our chemical compounds to cater to your specific requirements, providing you with chemicals that perfectly align with your unique application.

  • Compliance with Regulations

    We strictly comply with the industry-set regulations and guidelines during the production and transportation of MCA. This helps us to ensure adherence to safety and environmental regulations.

  • Customer Support

    We emphasize building strong relationships with our valued customers. We provide excellent technical assistance and sales support and cater to specific requirements to ensure a seamless experience from purchase to chemical utilization.

What is Monochloroacetic acid?

It is a versatile chemical compound with the chemical formula C2HCl3O2. It is a colorless, water-soluble organic compound. It is a strong acid extensively used in various chemical intermediates to produce multiple compounds.

What are the common applications of Monochloroacetic acid?

The Monochloroacetic acid Manufacturers in Gujarat provide this versatile chemical compound for various industrial applications. It is widely used in manufacturing products, including herbicides, surfactants, pharmaceuticals, etc. It is primarily used in the production of carboxymethyl cellulose (CMC), which is used in applications like food additives, pharmaceuticals, and textiles.

Is Monochloroacetic acid hazardous?

Yes. It can cause severe skin and eye irritation and be harmful if inhaled or swallowed. This is why it must be handled properly, and safety precautions must be taken while working with it.

CAS: 79-11-8

Molecular Formula: C2H3ClO2

Names and Identifiers

Name Chloroacetic acid
Synonyms chloroacetate
Chloroacetic acid
acidechloroacetique
Monochloroacetic acid
Acidomonocloroacetico
acidemonochloracetique
Mono Chloro Acetic Acid
alpha-Chloroacetic acid
Chloroacetic acid, mono-
acidechloroacetique(french)
acidemonochloracetique(solide)
acidemonochloracetique(french)
acidemonochloracetique(solutions)
CAS 79-11-8
EINECS 201-178-4
InChI InChI=1/C2H3ClO2/c3-1-2(4)5/h1H2,(H,4,5)/p-1

Physico-chemical Properties

Molecular Formula C2H3ClO2
Molar Mass 94.5
Density 1.58
Melting Point 60-63 °C (lit.)
Boling Point 189 °C (lit.)
Flash Point 126°C
Water Solubility SOLUBLE
Solubility Soluble in methanol, acetone, diethyl ether, benzene, chloroform and ethanol.
Vapor Presure 0.75 mm Hg ( 20 °C)
Vapor Density 3.26 (vs air)
Appearance Liquid
Color White
Odor Penetrating, burning odor
Merck 14,2112
BRN 605438
pKa 2.85(at 25℃)
Storage Condition Store below +30°C.
Stability Stable. Deliquescent. Incompatible with strong bases, alkalies, most common metals, strong oxidizing agents.
Sensitive Hygroscopic
Explosive Limit 8%
Refractive Index 1.4330
Physical and Chemical Properties Colorless or light yellow crystals, irritating odor, easy deliquescence. There is a strong corrosive.
melting point 63 ℃(α-type)
boiling point 187.85 ℃
freezing point relative density 1.4040
refractive index 1.4330
flash point solubility: soluble in water and ethanol, most organic solvents such as ether.
Use Dye Industry for the production of indigo dyes; Pharmaceutical industry for the synthesis of caffeine, barbiturate, epinephrine; Pesticide industry for the manufacture of dimethoate, herbicides

Risk and Safety

Risk Codes R25 - Toxic if swallowed
R34 - Causes burns
R50 - Very Toxic to aquatic organisms
R40 - Limited evidence of a carcinogenic effect
R36/37/38 - Irritating to eyes, respiratory system and skin.
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed.
R38 - Irritating to the skin
Safety Description S23 - Do not breathe vapour.
S37 - Wear suitable gloves.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. 
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S16 - Keep away from sources of ignition.
S63 -
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs UN 1751 6.1/PG 2
WGK Germany 2
RTECS AF8575000
FLUKA BRAND F CODES 3
TSCA Yes
HS Code 29154000
Hazard Class 6.1
Packing Group II

Upstream Downstream Industry

Raw Materials Acetic acid
Acetic acid
Sulfur(α)
Sulfur(α)
Chlorine
Downstream Products Ethylenediaminetetraacetic acid
Glycine
Ethyl cyanoacetate
Ethylenediaminetetraacetic acid disodium salt
Ethylenediaminetetraacetic acid tetrasodium salt
Ethyl malonate
dimethoate
Glyphosate
dimethylammonium 2,4-dichlorophenoxyacetate

Nature

colorless or light yellow crystals, irritating odor, easy deliquescence. Strong corrosive, can corrode the skin, damage all non-precious metals, rubber and wood. Soluble in water and ethanol, ether and other most organic solvents. There are four types of crystals.

Preparation Method

  1. acetic acid chlorination glacial acetic acid reacts with chlorine gas at about 95 ℃ under sulfur catalysis to obtain chloroacetic acid product, which is then cooled, crystallized and filtered to remove the mother liquor to obtain the final cyanacetic acid product. The tail gas is sent to the absorption tower to recover hydrochloric acid.
  2. hydrolysis of trichloroethylene
  3. glycolic acid chloride method

Use

This product is an organic chemical raw materials, mainly used as pesticides, pharmaceuticals and dyes intermediates. Pesticide industry for the production of dimethoate, herbicide 2,4-D and butyl ester, 2,4 ,5-T, thiocyanacetic acid and a naphthalene acetic acid; Pharmaceutical industry for the synthesis of caffeine, barbiturate, epinephrine, vitamin B. And glycine; Used in the dye industry for the production of indigo dyes. Chloroacetic acid can also be used in the production of carboxymethyl cellulose (CMC) and non-ferrous metal flotation agent 2-200#, can also be used as a chromatographic analysis reagent.

Safety

  • This product is highly toxic, has strong irritation and corrosiveness, can cause burns infected with the skin, long-term exposure to its vapor can lead to olfactory dysfunction, Chronic nasopharyngitis, skin itching, dryness and desquamation. The rats were gavage with 10% solution with an LDso of 55mg/kg. Production equipment should be closed to prevent leakage. Operators should wear protective equipment, and the skin or eyes should be washed with plenty of water.
  • woven bag lined with plastic bag, 25kg or 50kg net weight of each bag. It can also be packed in PVC plastic barrels. Store in a cool and dry place to prevent rain and humidity. According to the general provisions of the storage and transportation of chemicals.

Supplementary Information

category
High toxicity grade
Acute oral toxicity-rat LD50: 580 mg/kg; Subcutaneous-mouse LD50: 250 mg/kg
Explosive hazard characteristics and explosive properties of air mixture
Flammable hazard characteristics: when exposed to heat, open flame combustion; Toxic phosgene generated by thermal decomposition; Corrosive
Storage and Transportation characteristics the warehouse is ventilated and dried at low temperature; It is stored separately from oxidants and alkalis.
Fire extinguishing agent foam, water mist, carbon dioxide
Occupational Standards TLV-TWA 0.5 mg/m; PEL 1 mg/m

 Production method

There are three main methods for industrial production of chloroacetic acid

  1. The acetic acid chlorination method is obtained by directly chlorination of acetic acid with chlorine gas in the presence of a catalyst such as iodine, phosphorus, sulfur or a halide of phosphorus and sulfur. In addition to the formation of chloroacetic acid, there are deep chlorination by-products such as dichloroacetic acid, trichloroacetic acid. The process is simple and the yield of chloroacetic acid can reach 92%.
  2. The trichloroethylene hydration method uses 93% sulfuric acid as a catalyst, and the reaction temperature is about 160-180 °c. Chloroacetic acid with high purity can be obtained by this method, and the yield can reach 90%, but more hydrochloric acid is by-product.
  3. The chloroethanol oxidation method was performed at 60 ° C. With 60% nitric acid, and the yield of chloroacetic acid was more than 90%. In North America to acetic acid chloride method, Western Europe to trichloroethylene water law.

China's production by acetic acid chlorination method: the quantitative glacial acetic acid is added to the reaction pot, with 3.5% sulfur powder by weight of glacial acetic acid as the catalyst, preheating to more than 90 ℃, and the appropriate amount of chlorine gas is introduced, two reaction pots were connected to each other with chlorine. The main pot was controlled at 98±2 ℃, and the auxiliary pot was controlled at 85-90 ℃, when the relative density of the materials in the reaction pan is 1.350(80 ° C.), the end point of the reaction is reached. The reactant is pumped to the acid tank, cooled and crystallized, and the liquid phase is a small amount of acetic acid, dichloroacetic acid, sulfur chloride and a small amount of chloroacetic acid. The crystal is separated and the mother liquor is pumped down to 38 ℃. About 150 of mother liquor is produced per ton of product and can be further chlorinated to dichloroacetic acid, methyl dichloroacetate and chloroform. Trichloroethylene water method at the same time the addition of water and hydrolysis: the reaction temperature of 160-180 deg C, the reaction concentration of sulfuric acid should be maintained at 93%, control the ratio of trichloroethylene and water. The consumption of sulfuric acid is not more than 30%, and 2.57t hydrochloric acid is produced as by-product. Industrial chloroacetic acid is colorless or slightly yellowish crystals. Raw material consumption quota: glacial acetic acid (98%)730kg/t, chlorine 860kg/t, sulfur 26kg/t.

  • There are many synthetic methods of chloroacetic acid, such as acetic acid chlorination, acetic anhydride catalyzed chlorination, trichloroethylene hydrolysis, glycolic acid chlorination, tetrachloroethane hydrolysis, etc. Acetic acid chlorination is mainly used in domestic industrial production, the advantage of this method is that no sulfuric acid is used, and the raw material price is cheap, CH3COOH + Cl2 & rarr;ClCH2COOH + HCl
  • add quantitative glacial acetic acid into the reaction pan, use 3.5% sulfur powder of glacial acetic acid mass as catalyst, preheat to above 90 ℃, start feeding appropriate amount of chlorine gas, and connect the two reaction pans with each other, the temperature of the main pot was controlled at (98±2)℃, and the temperature of the auxiliary pot was 85-90 ℃, and the chlorine gas flow rate was about 70kg/h. When the relative density of the materials in the reaction pot is 1.350(80 ° C.), the end point of the reaction is reached. The reactants were pumped to the acid tank, cooled to crystallize, the crystals were separated, and the mother liquor was drained below 38 °c to obtain the finished chloroacetic acid. In addition, some experiments show that, in addition to sulfur powder, acetic anhydride can also play a good catalytic effect on the above chlorination reaction under the same conditions, and the effect is better than that of sulfur powder.
  • also trichloroethylene water legal. Trichloroethylene reacts with concentrated sulfuric acid, the reaction temperature is 160~180 ℃, the sulfuric acid content is maintained at 93%, the ratio of trichloroethylene to water is controlled, and the reaction process is added and hydrolyzed with sulfuric acid to obtain monochloroacetic acid.

Reference Information

pH range of acid-base indicator discoloration < 1 at 800g/l at 20°C
Solvent Sterile water in sealed ampoule
Concentration 1 mCi/ml
Specific Activity 5-10 Ci/mmol
LogP 0.49 at 20℃
Use the dye industry is used for the production of indigo dyes, and the pharmaceutical industry is used for the synthesis of caffeine, barbiturate, epinephrine, etc, pesticide industry for the manufacture of dimethoate, herbicides, etc.
chloroacetic acid is an organic chemical raw materials, widely used in the production of pesticides, can be used for the synthesis of organophosphorus insecticides dimethoate, omethoate intermediate methyl chloroacetate, the intermediate of quetiapine, 2-hydroxyquinoline, herbicide 2,4-drop, 2,4-drop butyl ester, 2 methyl 4 chloride, glyphosate, imazol-Furon and plant growth regulator naphthylacetic acid, etc. Also used in dyes, pharmaceuticals, resins and other organic synthesis.
used in a wide range of organic synthesis materials. Dye Industry for the production of indigo, naphthalene amino acetic acid dyes; In the pharmaceutical industry for the synthesis of caffeine, barbiturate, epinephrine, vitamin B6, amino acetic acid, malonate and other drugs and intermediates; in the pesticide industry for the production of herbicides 2,4-D, butyl ester, 2,4,5-T, thiocyanacetic acid, α-naphthylacetic acid, glyphosate, alachlor, acetochlor, butachlor and insecticide dimethoate more than 20 kinds of pesticides; in the synthetic fiber industry for the production of carboxymethyl cellulose (CMC) and non-ferrous metal flotation agent Z-200#, can also be used as a color layer analysis reagent, can also be used for food additives, detergents, cold Red fine and other products. See the chloroacetic acid series products in the attached table of this article for details.
as an excellent flame retardant for polyamide, PVC can replace part of antimony trioxide in flame retardant and smoke suppression, and has good lubricity
production method There are three main methods for the industrial production of chloroacetic acid. (1) the acetic acid chlorination method is obtained by directly chlorination of acetic acid with chlorine gas in the presence of a catalyst such as iodine, phosphorus, sulfur or a halide of phosphorus and sulfur. In addition to the formation of chloroacetic acid, there are deep chlorination by-products such as dichloroacetic acid, trichloroacetic acid. The process is simple and the yield of chloroacetic acid can reach 92%. (2) trichloroethylene hydration method is based on 93% sulfuric acid as catalyst, reaction temperature is about 160-180 deg C. Chloroacetic acid with high purity can be obtained by this method, and the yield can reach 90%, but more hydrochloric acid is by-product. (3) the chloroethanol oxidation method is oxidation with 60% nitric acid at 60 ° C., and the yield of chloroacetic acid is more than 90%. In North America to acetic acid chloride method, Western Europe to trichloroethylene water law. China's production by acetic acid chlorination method: the quantitative glacial acetic acid is added to the reaction pot, with 3.5% sulfur powder by weight of glacial acetic acid as catalyst, preheating to more than 90 degrees Celsius, and the appropriate amount of chlorine gas is introduced, two reaction pots were connected to each other with chlorine. The main pot was controlled at 98±2 ℃, and the auxiliary pot was controlled at 85-90 ℃, the relative density of the materials in the reaction pan is 1.350(80 C). When, that is, the reaction reaches the end point. The reactant is pumped to the acid tank, cooled and crystallized, and the liquid phase is a small amount of acetic acid, dichloroacetic acid, sulfur chloride and a small amount of chloroacetic acid. The crystal is separated and the mother liquor is pumped down to 38 ℃. About 150 of mother liquor is produced per ton of product and can be further chlorinated to dichloroacetic acid, methyl dichloroacetate and chloroform. Trichloroethylene water method at the same time the addition of water and hydrolysis: the reaction temperature of 160-180 deg C, the reaction concentration of sulfuric acid should be maintained at 93%, control the ratio of trichloroethylene and water. The consumption of sulfuric acid is not more than 30%, and 2.57t hydrochloric acid is produced as by-product. Industrial chloroacetic acid is colorless or slightly yellowish crystals. Raw material consumption quota: glacial acetic acid (98%)730kg/t, chlorine 860kg/t, sulfur 26kg/t.
There are many synthetic methods of chloroacetic acid, such as acetic acid chlorination, acetic anhydride catalyzed chlorination, trichloroethylene hydrolysis, glycolic acid chlorination, tetrachloroethane hydrolysis, etc, the advantage of this method is that no sulfuric acid is used, and the raw material price is cheap, CH3COOH + Cl2 → ClCH2COOH + HCl quantitative glacial acetic acid is added to the reaction pot, 3.5% sulfur powder of glacial acetic acid mass is used as catalyst, after preheating to more than 90 ℃, the appropriate amount of chlorine gas is introduced, and the two reaction pots are connected with each other. The control temperature of the main pot is (98±2)℃, and the auxiliary pot is 85~90 ℃, the chlorine gas flow rate was about 70kg/h. The relative density of the materials in the reaction pan is 1.350(80 C). The end point of the reaction is reached. The reactants were pumped to the acid tank, cooled to crystallize, the crystals were separated, and the mother liquor was drained below 38 °c to obtain the finished chloroacetic acid. In addition, some experiments show that, in addition to sulfur powder, acetic anhydride can also play a good catalytic effect on the above chlorination reaction under the same conditions, and the effect is better than that of sulfur powder. Also trichloroethylene water legal. Trichloroethylene reacts with concentrated sulfuric acid, the reaction temperature is 160~180 ℃, the sulfuric acid content is maintained at 93%, the ratio of trichloroethylene to water is controlled, and the reaction process is added and hydrolyzed with sulfuric acid to obtain monochloroacetic acid.
category corrosive article
toxicity grade high toxicity
Acute toxicity oral-rat LD50: 580 mg/kg; Subcutaneous-mouse LD50: 250 mg/kg
explosive hazard characteristics explosive when mixed with air
flammability hazard characteristics when heated, open flame combustion; Thermal decomposition to produce toxic phosgene; corrosive
storage and transportation characteristics The warehouse is ventilated and dried at low temperature; It is stored separately from oxidants and alkalis.
fire extinguishing agent foam, water mist, carbon dioxide
Occupational Standard TLV-TWA 0.5 mg/m3; Tel 1 mg/m3

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