We unleash your business potential by maximize the business innovation.
Send EmailDiethylamine, N-Ethylethanamine, DEA, 109-89-7
Product Name: Diethylamine (DEA)
Chemical Name: Diethylamine
CAS No: 109-89-7
EC No (EINECS): 203-716-3
Chemical Formula: C₄H₁₁N
Molecular Weight: 73.14 g/mol
REACH Status: Registered
| Parameter | Description |
|---|---|
| Chemical Name (IUPAC) | N-Ethylethanamine |
| Other Names | Diethylamine, DEA, Diethylamine, N-Ethylethanamine, DEA |
| CAS Number | 109-89-7 |
| EC Number (EINECS) | 203-716-3 |
| Molecular Formula | C₄H₁₁N |
| Molecular Weight | 73.14 g/mol |
| Chemical Class | Secondary amine, aliphatic amine |
| Appearance | Colorless to pale yellow liquid |
| Odor | Sharp amine odor |
| Taste | Not determined as technical product |
| REACH Status | Registered |
CHEMICAL STRUCTURE AND DESCRIPTION:
Diethylamine (DEA) is a secondary amine in which two ethyl groups are attached to a nitrogen atom. Its structure contains one secondary amine (-NH-) group. This structure gives DEA strong basic character and high reactivity.
Structural Formula (Open Structure):
CH₃-CH₂-NH-CH₂-CH₃
(N-Ethylethanamine)
These structural features:
Give DEA one reactive secondary amine group.
Make it a building block in the synthesis of rubber chemicals, pesticides, dyes, and pharmaceutical intermediates.
Allow its use as a catalyst and intermediate in organic syntheses.
Enable it to form salts with acids due to its strong basic character.
Diethylamine is a secondary amine widely used in rubber chemicals production, pesticide and herbicide synthesis, dye and pigment industry, pharmaceutical intermediates, and as a catalyst and intermediate in organic syntheses.
| Property | Value |
|---|---|
| Molecular Formula | C₄H₁₁N |
| Molecular Weight | 73.14 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Odor | Sharp amine odor |
| Density (20 °C) | 0.707 g/cm³ |
| Boiling Point | ~55 °C |
| Melting Point | -50 °C |
| Flash Point | -20 °C (closed cup) |
| Vapor Pressure (20 °C) | 400 mmHg |
| Viscosity (20 °C) | ~0.3 mPa·s |
| Surface Tension | ~20 mN/m (20 °C) |
| Refractive Index (20 °C) | ~1.385 |
| Solubility | Completely miscible with water; compatible with organic solvents |
| Stability | Stable under recommended storage conditions |
| pH (aqueous solution) | Strongly basic (pH > 12) |
| Volatility | High |
| Hygroscopicity | May absorb moisture; store in dry conditions |
Diethylamine is a colorless to pale yellow liquid. Its boiling point is ~55 °C, melting point -50 °C. Its density is 0.707 g/cm³ (20 °C), flash point -20 °C. Its vapor pressure is 400 mmHg at 20 °C. It is completely miscible with water. It exhibits strong basic character. It has high volatility.
| Solvent | Solubility | Conditions |
|---|---|---|
| Water | Completely miscible | 20 °C |
| Methanol | Miscible | - |
| Ethanol | Miscible | - |
| Isopropanol | Miscible | - |
| Acetone | Miscible | - |
| Ethyl acetate | Miscible | - |
| Hexane | Miscible | - |
| Toluene | Miscible | - |
| Xylene | Miscible | - |
| Glycols | Miscible | - |
Diethylamine is miscible with a wide range of polar and non-polar solvents. It is completely miscible with water. This property makes it useful in various formulations.
| Property | Description |
|---|---|
| Chemical Class | Secondary amine, aliphatic amine |
| Reactivity | Neutralization, alkylation, amidation, urethane formation, Mannich reaction |
| Basicity | Strongly basic (pKa ~10.98) |
| Hydrolytic Stability | High |
| Thermal Stability | Good |
| Oxidation Resistance | Moderate; tendency to yellow in air |
| Polymerization | Does not undergo hazardous spontaneous polymerization |
| Compatibility | Acids, anhydrides, isocyanates, alkyl halides, epoxy resins |
| Substances to Avoid | Strong oxidizing agents, strong acids, carbon dioxide |
| Hazardous Decomposition Products | Nitrogen oxides (NOx), carbon monoxide (CO), carbon dioxide (CO₂), ammonia |
Thanks to its secondary amine group, diethylamine forms salts with acids, undergoes N-alkylation with alkyl halides, amidation with anhydrides, and urethane formation with isocyanates. It participates in the Mannich reaction. Due to its strongly basic character, it undergoes neutralization reactions in acidic media.
| Parameter | Specification |
|---|---|
| Purity (GC) | ≥ 99.0% |
| Appearance | Colorless to pale yellow liquid |
| Color (Pt-Co) | ≤ 20 Hazen |
| Water Content | ≤ 0.2% |
| Acid Value | ≤ 0.1 mg KOH/g |
| Density (20 °C) | 0.705–0.710 g/cm³ |
| Boiling Range | 54–56 °C |
| Flash Point | ≤ -20 °C |
| Refractive Index (20 °C) | 1.382–1.388 |
| Viscosity (20 °C) | 0.25–0.35 mPa·s |
| Heavy Metals | ≤ 10 ppm |
| Shelf Life | 12 months (under proper storage) |
Diethylamine is produced in technical grade with high purity. In industrial applications, batch-to-batch consistency, color stability, and low impurity content are important.
| Application | Description |
|---|---|
| Rubber Accelerators | In the production of vulcanization accelerators |
| Rubber Stabilizers | In the production of antioxidants and stabilizers |
| Vulcanization Agents | Chemicals used in rubber vulcanization |
Diethylamine is widely used in the rubber industry in the production of accelerators and stabilizers.
| Application | Description |
|---|---|
| Herbicides | In the synthesis of selective herbicides |
| Insecticides | In the production of certain insecticides |
| Fungicides | In the synthesis of agricultural chemicals |
| Pesticide Intermediates | Intermediate in active ingredient synthesis |
Diethylamine is used as an intermediate in the synthesis of pesticides and herbicides in agricultural chemicals.
| Application | Description |
|---|---|
| Dyestuffs | In the synthesis of azo dyes |
| Pigments | In the production of organic pigments |
| Textile Dyes | In the synthesis of textile dyes |
| Inks | In some ink formulations |
Diethylamine is used in the dye and pigment industry in dyestuff synthesis.
| Application | Description |
|---|---|
| Pharmaceutical Intermediates | In the synthesis of drug active ingredients |
| Local Anesthetics | In the production of certain local anesthetics |
| Antihistamines | In the synthesis of antihistamine drugs |
| Diuretics | In the production of certain diuretics |
Diethylamine is used in the pharmaceutical industry in the synthesis of various pharmaceutical intermediates.
| Application | Description |
|---|---|
| Catalyst | Base catalyst in organic reactions |
| Mannich Reaction | In the synthesis of Mannich bases |
| N-Alkylation | In the synthesis of N-alkyl amines |
| Amidation | In the synthesis of amides and imides |
Diethylamine is widely used as a catalyst and intermediate in organic syntheses.
| Application | Description |
|---|---|
| Corrosion Inhibitors | Corrosion prevention on metal surfaces |
| Surfactants | Cationic surfactant synthesis |
| Ion Exchangers | Anion exchange resins |
| Textiles | Softener and dye auxiliary |
| Property | Description |
|---|---|
| Structural Class | Secondary amine, aliphatic amine |
| Functional Groups | One secondary amine (-NH-) |
| Basicity | Strongly basic (pKa ~10.98) |
| Volatility | High |
| Evaporation Profile | High, fast |
| Water Miscibility | Completely miscible |
| Polarity | High polarity |
| Reactivity | High; neutralization, alkylation, amidation |
The secondary amine group of diethylamine gives it high reactivity and versatile functionality.
| Application | Description |
|---|---|
| Neutralization | Salt formation with acids |
| Alkylation | N-alkylation with alkyl halides |
| Amidation | Amide formation with acids |
| Urethane Formation | Reaction with isocyanates |
| Mannich Reaction | Synthesis of Mannich bases |
| Catalyst | Use as base catalyst |
| Parameter | Value |
|---|---|
| GHS Classification | Flam. Liq. 2 (H225), Acute Tox. 3 (H311, H331), Acute Tox. 4 (H302), Skin Corr. 1B (H314) |
| Oral LD50 (Rat) | ~540 mg/kg |
| Dermal LD50 (Rabbit) | ~580 mg/kg |
| Skin Irritation | Causes severe skin burns (H314) |
| Eye Irritation | Causes serious eye damage (H314) |
| Respiratory Irritation | Toxic if inhaled (H331); irritates respiratory tract |
| Skin Sensitization | Not expected |
| Mutagenicity | Not classified |
| Carcinogenicity | Not classified |
| Bioaccumulation | Not likely |
| WGK Germany | 2 (hazardous to water) |
Diethylamine is a highly flammable, toxic, and corrosive chemical. It causes severe burns on contact with skin and eyes. Inhalation and skin contact are toxic. It is harmful if swallowed. Appropriate PPE must be used in industrial handling.
| Parameter | Information |
|---|---|
| UN Number | UN 1154 |
| Hazard Class | 3 (Flammable liquids) / 8 (Corrosive substances) |
| Packing Group | II |
| Proper Shipping Name | Diethylamine |
| Marine Pollutant | No |
| ADR/RID Label | Class 3 (8) |
| Transport Regulations | Must be transported in accordance with ADR/RID/IMDG/IATA rules |
Diethylamine is classified as a flammable and corrosive liquid. Transport must comply with ADR/RID/IMDG/IATA regulations.
| Region | Status |
|---|---|
| EU | REACH registered |
| USA (TSCA) | Listed |
| EINECS | 203-716-3 |
| Turkey (KKDİK) | Should be evaluated within compliance and registration requirements |
| Food Contact | Not suitable for technical grade |
| Hazardous Substance | Yes (flammable, toxic, corrosive) |
| Parameter | Information |
|---|---|
| Storage Conditions | Store in a cool, dry, well-ventilated area |
| Temperature | 15–25 °C |
| Container Requirements | Closed containers, away from moisture and heat sources |
| Moisture Control | Dry environment to prevent moisture absorption |
| Substances to Avoid | Strong oxidizing agents, strong acids, carbon dioxide, ignition sources |
| Shelf Life | 12 months (under proper storage) |
| Handling Notes | Avoid breathing vapor; use PPE |
| Packaging Options | 200 L steel drums, IBC tanks, bulk delivery; custom packaging upon request |
Handling Notes:
Avoid breathing vapor.
Use appropriate personal protective equipment (gloves, goggles, mask).
Avoid contact with skin and eyes.
Keep away from ignition sources.
| Parameter | Information |
|---|---|
| Fire Hazard | Highly flammable liquid; vapor/air mixture may ignite easily |
| Flash Point | -20 °C (closed cup) |
| Extinguishing Media | Water spray, foam, CO₂, dry chemical powder |
| Special Hazards | Thermal decomposition may release NOx, CO, CO₂, and ammonia |
| Protective Equipment | Self-contained breathing apparatus (SCBA), full protective clothing |
Diethylamine is a highly flammable liquid. In case of fire, appropriate extinguishing media should be used, and firefighting personnel should wear protective equipment.
| Parameter | Information |
|---|---|
| Personal Protection | Respirator, protective goggles, gloves, protective clothing |
| Ventilation | Ventilate the area |
| Containment | Contain the spill |
| Cleaning Methods | Absorb with inert material; place in suitable disposal container |
| Environmental Precautions | Prevent entry into drains, sewers, and water sources |
| Waste Disposal | Dispose of according to local regulations |
In case of a spill, clean up while preventing vapor formation. Dispose of waste properly. Prevent environmental release.
| Exposure Route | Action |
|---|---|
| Inhalation | Move to fresh air; seek medical attention if symptoms persist |
| Skin Contact | Wash with plenty of water, remove contaminated clothing, seek immediate medical attention |
| Eye Contact | Rinse with water for at least 15 minutes, seek immediate medical attention |
| Ingestion | Do not induce vomiting; seek immediate medical attention |
| Raw Material | Description |
|---|---|
| Ethanol | Precursor in diethylamine synthesis |
| Ammonia | Used in amination reaction |
| Ethylene | Used in alkylation reaction |
| Acetaldehyde | Intermediate |
| By-Product | Application |
|---|---|
| Diethylamine Salts | Pharmaceutical active ingredients |
| Rubber Accelerators | Rubber vulcanization |
| Pesticides | Agricultural chemicals |
| Dyestuffs | Dye and pigment industry |
| Pharmaceutical Intermediates | Drug synthesis |
| Industry | Application Area | Example Use | Suitability |
|---|---|---|---|
| Rubber | Accelerator, stabilizer | Vulcanization chemicals | High |
| Agriculture | Pesticide, herbicide | Agricultural chemicals | High |
| Dye and Pigment | Dyestuff synthesis | Azo dyes, pigments | High |
| Pharmaceutical | Intermediate | Pharmaceutical synthesis | High |
| Organic Synthesis | Catalyst, intermediate | Mannich reaction, N-alkylation | High |
| Corrosion | Inhibitor | Metal protection | Suitable |
Diethylamine can undergo many chemical reactions due to its secondary amine group:
| Reaction | Description |
|---|---|
| Neutralization | Salt formation with acids |
| Alkylation | N-alkylation with alkyl halides |
| Amidation | Amide formation with carboxylic acids |
| Urethane Formation | Urethane formation with isocyanates |
| Mannich Reaction | Synthesis of Mannich bases |
| Carbamate Formation | Carbamate formation with CO₂ |
Diethylamine derivatives are widely used in rubber, agriculture, dyes, pharmaceuticals, and organic synthesis.
| Compound | Description |
|---|---|
| Diethylamine Salts | Pharmaceutical salts |
| N,N-Diethylaminoethanol | Pharmaceutical and cosmetic intermediate |
| Diethylhydroxylamine | Rubber stabilizer |
| Diethyldithiocarbamate | Rubber accelerator |
| Triethylamine | Similar amine; catalyst |
| Ethylamine | Similar amine; chemical intermediate |
SUMMARY:
Diethylamine (DEA) is a colorless to pale yellow liquid with the formula C₄H₁₁N and CAS number 109-89-7. It is a secondary amine. It is widely used in rubber chemicals production, pesticide and herbicide synthesis, dye and pigment industry, pharmaceutical intermediates, and as a catalyst and intermediate in organic syntheses. It exhibits strong basic character. It is completely miscible with water. It is a highly flammable, toxic, and corrosive chemical; it causes severe burns to skin and eyes. Inhalation and skin contact are toxic. It should be stored in a cool, dry, and well-ventilated area in tightly closed containers.
Key Properties:
| Property | Value |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Chemical Formula | C₄H₁₁N |
| Molecular Weight | 73.14 g/mol |
| CAS Number | 109-89-7 |
| Boiling Point | ~55 °C |
| Melting Point | -50 °C |
| Density | 0.707 g/cm³ (20 °C) |
| Flash Point | -20 °C (closed cup) |
| Vapor Pressure | 400 mmHg (20 °C) |
| Solubility | Completely miscible with water |
| Chemical Class | Secondary amine, aliphatic amine |
| Primary Use | Rubber chemicals, pesticides, dyes, pharmaceutical intermediates |
Main Applications:
| Industry | Applications |
|---|---|
| Rubber | Accelerator, stabilizer |
| Agriculture | Pesticide, herbicide |
| Dye and Pigment | Dyestuff synthesis |
| Pharmaceutical | Intermediate |
| Organic Synthesis | Catalyst, intermediate |
| Corrosion | Inhibitor |
Key Safety Points:
HIGHLY FLAMMABLE: Flam. Liq. 2 (H225)
TOXIC: Acute Tox. 3 (H311, H331), Acute Tox. 4 (H302)
CORROSIVE: Skin Corr. 1B (H314) – causes severe skin burns and eye damage
STORAGE: 15–25 °C, cool, dry, well-ventilated
PPE RECOMMENDED: Gloves, protective goggles, respirator, protective clothing
INCOMPATIBLE: Strong oxidizing agents, strong acids, carbon dioxide, ignition sources
CRITICAL WARNINGS:
Diethylamine is a secondary amine. It shows high reactivity.
It is used in the synthesis of rubber chemicals, pesticides, dyes, and pharmaceutical intermediates.
It acts as a catalyst and intermediate in organic syntheses.
It exhibits strong basic character; it undergoes neutralization reactions in acidic media.
It is a highly flammable liquid; it should be kept away from ignition sources.
It is a toxic and corrosive chemical; it causes severe burns to skin and eyes.
Inhalation and skin contact are toxic; breathing vapor should be avoided.
Environmental release must be prevented; it is hazardous to water.
It should be stored in tightly closed containers to prevent moisture absorption.
Important Statement: This Technical Data Sheet (TDS) is for informational purposes only. The information provided is based on available data and is believed to be accurate. However, the user is solely responsible for determining the suitability of the product for their own specific applications and for complying with all applicable regulations and safety requirements. For complete safety, use, storage, and regulatory compliance information, always refer to the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier. Users are obligated to test the product in their own processes and applications. All local, national, and international regulations must be followed when working with Diethylamine.