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Send EmailEthylene Glycol Diacetate, Ethylene Diacetate, Glycol Diacetate, Ethanediol Diacetate, EDGA, 111-55-7
Product Name: Ethylene Glycol Diacetate (EGDA)
Chemical Name: Ethylene Glycol Diacetate
CAS No: 111-55-7
EC No (EINECS): 203-881-8
Chemical Formula: C₆H₁₀O₄
Molecular Weight: 146.14 g/mol
REACH Status: Registered
| Parameter | Description |
|---|---|
| Chemical Name (IUPAC) | Ethane-1,2-diyl diacetate |
| Other Names | Ethylene Glycol Diacetate, EGDA, Ethylene Glycol Diacetate, Ethylene Diacetate, Glycol Diacetate, 1,2-Ethanediol diacetate |
| CAS Number | 111-55-7 |
| EC Number (EINECS) | 203-881-8 |
| Molecular Formula | C₆H₁₀O₄ |
| Molecular Weight | 146.14 g/mol |
| Chemical Class | Diester, glycol diester |
| Appearance | Colorless liquid |
| Odor | Mild characteristic, ester-like |
| Taste | Not determined as technical product |
| REACH Status | Registered |
CHEMICAL STRUCTURE AND DESCRIPTION:
Ethylene Glycol Diacetate (EGDA) is a glycol diester formed by complete esterification of ethylene glycol with acetic acid. Its structure contains two ester (-COO-) groups; it does not contain a hydroxyl group. This structure gives EGDA high solvency power and chemical stability.
Structural Formula (Open Structure):
CH₃-COO-CH₂-CH₂-OOC-CH₃
(Ethane-1,2-diyl diacetate)
These structural features:
Give EGDA excellent solvent properties.
Provide a high boiling point and low volatility.
Find wide use in coatings, inks, adhesives, textiles, pharmaceuticals, cosmetics, and electronics.
Are used as an intermediate in the production of other esters in organic syntheses.
EGDA is a colorless, high-boiling diester solvent. It is widely used in many industrial fields such as coatings, inks, adhesives, textiles, pharmaceuticals, cosmetics, electronics, and plastics processing.
| Property | Value |
|---|---|
| Molecular Formula | C₆H₁₀O₄ |
| Molecular Weight | 146.14 g/mol |
| Appearance | Colorless liquid |
| Odor | Mild characteristic, ester-like |
| Purity (GC) | ≥ 99.0% |
| Diester Content | ≥ 99.0% |
| Color (Pt-Co) | ≤ 10 |
| Water Content | ≤ 0.1% |
| Acidity (NaOH) | ≤ 0.1 mg/g |
| Density (20 °C) | ~1.10 g/cm³ (typical) |
| Refractive Index (n20D) | ~1.415 (typical) |
| Boiling Point (760 mmHg) | ~190–191 °C (typical) |
| Flash Point (Closed Cup) | ~88 °C (typical) |
| Solubility | Miscible with water and most organic solvents |
| Stability | Stable under recommended storage conditions |
| Volatility | Low |
| Hygroscopicity | May absorb slight moisture; store in dry conditions |
EGDA is a colorless liquid. Its density is ~1.10 g/cm³ (20 °C), refractive index ~1.415. Its boiling point is ~190–191 °C, flash point ~88 °C (closed cup). It is miscible with water and most organic solvents. It has low volatility and good chemical stability.
| Solvent | Solubility | Conditions |
|---|---|---|
| Water | Miscible | 20 °C |
| Methanol | Miscible | - |
| Ethanol | Miscible | - |
| Isopropanol | Miscible | - |
| Acetone | Miscible | - |
| Ethyl acetate | Miscible | - |
| Ether | Miscible | - |
| Toluene | Miscible | - |
| Xylene | Miscible | - |
| Glycols | Miscible | - |
EGDA is miscible with a wide range of polar and non-polar solvents. It is completely miscible with water. This property makes it useful in various formulations.
| Property | Description |
|---|---|
| Chemical Class | Diester, glycol diester |
| Reactivity | Hydrolysis, transesterification, esterification |
| Hydrolytic Stability | Moderate; may hydrolyze under acidic/basic conditions |
| Thermal Stability | Good |
| Oxidation Resistance | Good |
| Polymerization | Does not undergo hazardous spontaneous polymerization |
| Compatibility | Carboxylic acids, anhydrides, isocyanates, esters |
| Substances to Avoid | Strong oxidizing agents, strong acids, strong bases |
| Hazardous Decomposition Products | Carbon monoxide (CO), carbon dioxide (CO₂), acetic acid vapor |
EGDA is a diester containing two ester groups. Since it does not contain a hydroxyl group, it does not undergo esterification reactions; however, it is prone to hydrolysis and transesterification. EGDA is generally used as a solvent and serves as an intermediate in organic syntheses.
| Parameter | Specification |
|---|---|
| Purity (GC) | ≥ 99.0% |
| Diester Content | ≥ 99.0% |
| Appearance | Colorless liquid |
| Color (Pt-Co) | ≤ 10 |
| Water Content | ≤ 0.1% |
| Acidity (NaOH) | ≤ 0.1 mg/g |
| Density (20 °C) | ~1.10 g/cm³ (typical) |
| Refractive Index (20 °C) | ~1.415 (typical) |
| Boiling Range | ~190–191 °C |
| Flash Point | ~88 °C |
| Heavy Metals | ≤ 10 ppm |
| Shelf Life | 24 months (under proper storage) |
EGDA is produced in technical grade with high purity. In industrial applications, batch-to-batch consistency, color stability, and low impurity content are important.
| Application | Description |
|---|---|
| Coatings | Used as a solvent and flow modifier |
| Inks | Solvent and viscosity modifier |
| Adhesives | Solvent and adhesion promoter |
| Cleaners | Solvent in industrial cleaners |
EGDA is a widely used solvent in the coating, ink, and adhesive industries. Thanks to its high boiling point and low volatility, it provides controlled evaporation.
| Application | Description |
|---|---|
| Dye Carrier | Carrier solvent in textile dyeing processes |
| Softener | Used in textile softener formulations |
| Processing Solutions | Solvent in textile processing solutions |
EGDA is used as a dye carrier and softener in the textile industry.
| Application | Description |
|---|---|
| Intermediate | Intermediate in drug synthesis |
| Solvent | Solvent in cosmetic formulations |
| Fixative | Fixative in some cosmetic products |
EGDA is used as an intermediate, solvent, and fixative in the pharmaceutical and cosmetic industries.
| Application | Description |
|---|---|
| Circuit Cleaner | Solvent for cleaning electronic circuits |
| Photolithography Solvent | Solvent in photolithography processes |
| Precision Cleaning | Used for cleaning sensitive surfaces |
EGDA is used as a circuit cleaner and photolithography solvent in the electronics industry.
| Application | Description |
|---|---|
| Plastic Additive | Additive in plastics processing |
| Plasticizer | Ester derivatives used as plasticizers |
| Polymer Processing | Polymer processing aid |
EGDA is used as an additive and plasticizer in the plastics processing industry.
| Application | Description |
|---|---|
| Ester Production | Intermediate in the production of other esters |
| Transesterification | Used in ester exchange reactions |
| Chemical Intermediate | Intermediate in various organic syntheses |
EGDA is used as an intermediate in the production of other esters in organic syntheses.
| Property | Description |
|---|---|
| Structural Class | Diester, glycol diester |
| Functional Groups | Two ester (-COO-) groups |
| Hydroxyl Group | None |
| Solvency Power | High |
| Evaporation Profile | Low, controlled |
| Water Miscibility | Completely miscible |
| Polarity | Medium polarity |
| Polymer Contribution | Solvent, plasticizer, intermediate |
The structure of EGDA containing two ester groups makes it a strong solvent and chemical intermediate.
| Application | Description |
|---|---|
| Solvent Formulation | Solvent in coatings, inks, adhesives, and cleaners |
| Transesterification | Used in ester exchange reactions |
| Hydrolysis | Hydrolyzes under acidic/basic conditions |
| Polymer Processing | Additive in plastics processing |
| Electronic Cleaning | Solvent in circuit and photolithography cleaning |
| Organic Synthesis | Intermediate in the production of other esters |
| Parameter | Value |
|---|---|
| GHS Classification | Not classified as a hazardous substance |
| Oral LD50 (Rat) | > 2000 mg/kg (estimated) |
| Dermal LD50 (Rabbit) | > 2000 mg/kg (estimated) |
| Skin Irritation | May be mildly irritating |
| Eye Irritation | May be mildly irritating |
| Respiratory Irritation | Vapor inhalation may cause mild irritation |
| Skin Sensitization | Not expected |
| Mutagenicity | Not classified |
| Carcinogenicity | Not classified |
| Bioaccumulation | Not likely |
| WGK Germany | 1 (slightly hazardous to water) |
EGDA is a chemical with low toxicity. It may cause mild irritation on contact with eyes and skin. Vapor inhalation may cause mild respiratory discomfort. It is not classified as a hazardous substance, but appropriate PPE should be used in industrial handling.
| Parameter | Information |
|---|---|
| UN Number | Not applicable (not a hazardous substance) |
| Hazard Class | Not a hazardous substance |
| Packing Group | Not applicable |
| Proper Shipping Name | Ethylene Glycol Diacetate (EGDA) |
| Marine Pollutant | No |
| ADR/RID Label | Not applicable |
EGDA is not classified as a hazardous substance. There are no special restrictions for its transport by sea, land, or air.
| Region | Status |
|---|---|
| EU | REACH registered |
| USA (TSCA) | Listed |
| EINECS | 203-881-8 |
| Turkey (KKDİK) | Should be evaluated within compliance and registration requirements |
| Food Contact | Not suitable for technical grade; special grade required for food contact |
| Hazardous Substance | No |
| Parameter | Information |
|---|---|
| Storage Conditions | Cool, dry, well-ventilated area |
| Temperature | 15–25 °C (ideal); should not exceed 40 °C |
| Container Requirements | Tightly closed container |
| Moisture Control | Dry environment to prevent moisture absorption |
| Substances to Avoid | Strong oxidizing agents, direct sunlight, ignition sources |
| Shelf Life | 24 months (under proper storage) |
| Handling Notes | Avoid breathing vapor; use PPE |
| Packaging Options | 220 kg iron drum or IBC; custom packaging upon request |
Handling Notes:
Avoid breathing vapor.
Use appropriate personal protective equipment (gloves, goggles, mask).
Avoid contact with skin and eyes.
Keep away from ignition sources.
| Parameter | Information |
|---|---|
| Fire Hazard | Combustible liquid; vapor/air mixture may be flammable |
| Flash Point | ~88 °C (closed cup) |
| Extinguishing Media | Water spray, foam, CO₂, dry chemical powder |
| Special Hazards | Thermal decomposition may release CO, CO₂, and acetic acid vapor |
| Protective Equipment | Self-contained breathing apparatus (SCBA), full protective clothing |
EGDA is a combustible liquid. In case of fire, appropriate extinguishing media should be used, and firefighting personnel should wear protective equipment.
| Parameter | Information |
|---|---|
| Personal Protection | Respirator, protective goggles, gloves, protective clothing |
| Ventilation | Ventilate the area |
| Containment | Contain the spill |
| Cleaning Methods | Absorb with inert material; place in suitable disposal container |
| Environmental Precautions | Prevent entry into drains, sewers, and water sources |
| Waste Disposal | Dispose of according to local regulations |
In case of a spill, clean up while preventing vapor formation. Dispose of waste properly. Prevent environmental release.
| Exposure Route | Action |
|---|---|
| Inhalation | Move the person to fresh air. Seek medical attention if irritation persists. |
| Skin Contact | Wash with plenty of water and soap. Remove contaminated clothing. |
| Eye Contact | Rinse with plenty of water for at least 15 minutes. Seek medical attention if irritation persists. |
| Ingestion | Rinse mouth with water. Drink plenty of water. Do not induce vomiting. Seek medical attention. |
| Raw Material | Description |
|---|---|
| Ethylene Glycol | Precursor in EGDA synthesis |
| Acetic Acid | Used in esterification reaction |
| Acetic Anhydride | Used in esterification reaction |
| Catalyst | Acidic catalysts (sulfuric acid, p-toluenesulfonic acid) |
| By-Product | Application |
|---|---|
| Ethylene Glycol Monoacetate | Intermediate in EGDA production |
| Polyester Resins | Coatings, adhesives |
| Polyurethanes | Adhesives, elastomers |
| Plasticizers | Plastics and rubber industry |
| Industry | Application Area | Example Use | Suitability |
|---|---|---|---|
| Coatings | Solvent | Paints, inks, adhesives | High |
| Textiles | Dye carrier, softener | Textile dyeing and processing | High |
| Pharmaceuticals & Cosmetics | Intermediate, solvent, fixative | Drug synthesis, cosmetic products | Suitable |
| Electronics | Circuit cleaner, photolithography solvent | Electronic cleaning | High |
| Plastics Processing | Plastic additive | Plastics and polymer processing | Suitable |
| Organic Synthesis | Ester production | Synthesis of other esters | High |
EGDA can undergo many chemical reactions due to its two ester groups:
| Reaction | Description |
|---|---|
| Hydrolysis | Hydrolyzes under acidic/basic conditions |
| Transesterification | Reacts with esters to perform ester exchange |
| Esterification | Does not react with carboxylic acids (no hydroxyl group) |
| Aminolysis | Reacts with amines to form amides |
EGDA derivatives are widely used in coatings, adhesives, plastics, and pharmaceutical products.
| Compound | Description |
|---|---|
| Ethylene Glycol Monoacetate (EGMA) | Intermediate in EGDA production; monoester |
| Ethylene Glycol | Raw material in EGDA production |
| Acetic Acid | Raw material in EGDA production |
| Propylene Glycol Diacetate | Similar glycol diester |
| Diethylene Glycol Diacetate | Similar glycol diester |
SUMMARY:
Ethylene Glycol Diacetate (EGDA) is a colorless liquid with the formula C₆H₁₀O₄ and CAS number 111-55-7. It is a glycol diester containing two ester groups. It has a high boiling point and low volatility. It is widely used in coatings, inks, adhesives, textiles, pharmaceuticals, cosmetics, electronics, and plastics processing. It serves as an intermediate in the production of other esters in organic syntheses. It has low toxicity and is not classified as a hazardous substance. It should be stored in a cool, dry, and well-ventilated area in tightly closed containers.
Key Properties:
| Property | Value |
|---|---|
| Appearance | Colorless liquid |
| Chemical Formula | C₆H₁₀O₄ |
| Molecular Weight | 146.14 g/mol |
| CAS Number | 111-55-7 |
| Purity (GC) | ≥ 99.0% |
| Diester Content | ≥ 99.0% |
| Color (Pt-Co) | ≤ 10 |
| Water Content | ≤ 0.1% |
| Acidity (NaOH) | ≤ 0.1 mg/g |
| Chemical Class | Diester, glycol diester |
| Primary Use | Solvent, intermediate, plastic additive |
Main Applications:
| Industry | Applications |
|---|---|
| Coatings | Paints, inks, adhesives |
| Textiles | Dye carrier, softener |
| Pharmaceuticals & Cosmetics | Intermediate, solvent, fixative |
| Electronics | Circuit cleaner, photolithography solvent |
| Plastics Processing | Plastic additive |
| Organic Synthesis | Production of other esters |
Key Safety Points:
LOW TOXICITY: Not a hazardous substance; LD50 > 2000 mg/kg (estimated)
MILD IRRITATION: May cause mild irritation to eyes and skin
VAPOR CONTROL: Inhalation of vapor should be avoided
STORAGE: Cool, dry, well-ventilated; should not exceed 40 °C
PPE RECOMMENDED: Gloves, protective goggles, respirator
INCOMPATIBLE: Strong oxidizing agents, ignition sources
CRITICAL WARNINGS:
EGDA is a glycol diester containing two ester groups. It does not contain a hydroxyl group.
It has a high boiling point and low volatility; it offers a controlled evaporation profile.
It is widely used in coatings, inks, adhesives, textiles, pharmaceuticals, cosmetics, electronics, and plastics processing.
It is used as an intermediate in the production of other esters in organic syntheses.
It is a combustible liquid; it should be kept away from ignition sources.
It is not classified as a hazardous substance; however, appropriate PPE should be used in industrial handling.
Vapor inhalation may mildly irritate the respiratory tract; good ventilation should be provided.
It should be stored in tightly closed containers to prevent moisture absorption.
| Property / Parameter | EGMA (Monoacetate) | EGDA (Diacetate) |
|---|---|---|
| CAS No. | 542-59-6 | 111-55-7 |
| Molecular Formula | C₄H₈O₃ | C₆H₁₀O₄ |
| Molecular Weight | 104.11 | 146.14 |
| Purity (GC) | ≥99.0% (99.3) | ≥99% |
| Color (Pt-Co) | ≤15 (7) | ≤10 |
| Water Content | ≤0.10% (0.05) | ≤0.1% |
| Acidity | ≤0.03% (0.01) | ≤0.1 mg/g |
| Density (20℃) | 1.105–1.115 (1.110) | Not specified |
| Refractive Index (n20D) | 1.418–1.422 (1.420) | Not specified |
| Boiling Point (760 mmHg) | 178–184 (179.1–182.6) | High boiling point (not specified) |
| Flash Point | ≥100 (103) | Not specified |
| Packaging | 220 kg iron drum | 220 kg Drum / IBC |
| Primary Use | Intermediate, limited solvent | Very broad solvent and industrial use |
Important Statement: This Technical Data Sheet (TDS) is for informational purposes only. The information provided is based on available data and is believed to be accurate. However, the user is solely responsible for determining the suitability of the product for their own specific applications and for complying with all applicable regulations and safety requirements. For complete safety, use, storage, and regulatory compliance information, always refer to the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier. Users are obligated to test the product in their own processes and applications. All local, national, and international regulations must be followed when working with EGDA.