Rhodiola Rosea Root Extract, Arctic Root Extract, Golden Root Extract, Roseroot Extract, 97404-52-9

RHODIOLA ROSEA ROOT EXTRACT 

1. PRODUCT IDENTIFICATION AND CHEMICAL IDENTITY

2. BOTANICAL DESCRIPTION AND NATURAL SOURCE

2.1. Plant Description

Rhodiola rosea (also known as Golden Root, Arctic Root) is a perennial plant belonging to the Crassulaceae family, growing in Arctic and mountainous regions. It is naturally found at altitudes of 2000-5000 meters in Siberia, Scandinavia, Iceland, Greenland, and the Himalayas. Traditionally, it has been used in Russia, Scandinavia, and Asia to combat fatigue, stress, and enhance mental performance.

2.2. Active Compounds

2.3. Chemical Structure

Rosavin (C₂₀H₂₈O₁₀):

        OH
         |
    CH₂ - CH - CH₂OH
         |
    C₆H₁₀O₅ (Glucose)

Salidroside (C₁₄H₂₀O₇):

text

    HO - CH₂ - CH₂ - C₆H₄ - OH
              |
         C₆H₁₁O₆ (Glucose)

3. PHYSICAL AND CHEMICAL PROPERTIES

4. BIOLOGICAL AND FUNCTIONAL PROPERTIES

4.1. Adaptogenic Mechanism of Action

Rhodiola rosea is known for its adaptogenic properties. It increases the body's resistance to physical, chemical, and biological stress factors. The mechanism of action involves modulation of the hypothalamic-pituitary-adrenal (HPA) axis, neurotransmitter regulation, and strengthening of antioxidant defense systems.

4.2. Biological Activities

4.3. Rosavin vs Salidroside Comparison

5. CLINICAL STUDIES AND EVIDENCE

5.1. Fatigue and Energy

5.2. Stress and Anxiety

5.3. Cognitive Function

6. APPLICATION AREAS

6.1. Dietary Supplements (Most Important Application)

6.2. Functional Foods and Beverages

6.3. Sports Nutrition

6.4. Cosmetics and Personal Care

7. DOSAGE AND USAGE RECOMMENDATIONS

7.1. Standard Dosage

7.2. Active Compound-Based Dosage

Note: Calculated based on 3% Rosavin, 1% Salidroside standardization. Clinical studies have used 200-600 mg/day. Medical conditions require physician consultation.

8. BIOAVAILABILITY AND METABOLISM

9. SAFETY AND TOXICOLOGY

Overdose Symptoms:

• Nausea (at high doses)

• Dizziness

• Sleep disturbances (at very high doses)

10. GHS CLASSIFICATION

Signal Word: None

Hazard Pictograms: None

Hazard Statements: No H-codes

11. PRECAUTIONARY STATEMENTS (P-CODES)

12. FIRST AID MEASURES

13. STORAGE AND SHELF LIFE

14. PACKAGING OPTIONS

15. TRANSPORT INFORMATION

16. REGULATORY STATUS

17. QUALITY SPECIFICATIONS

18. OTHER NAMES AND SYNONYMS

• Rhodiola Rosea Root Extract

• Arctic Root Extract

• Golden Root Extract

• Roseroot Extract

• Rhodiola Extract

• Golden Root Extract (Altın Kök Ekstresi)

• Arctic Root Extract (Kutup Kökü Ekstresi)

• Rhodiola rosea (INCI)

19. QUICK REFERENCE TABLE

20. CRITICAL NOTICES AND BEST PRACTICES

CRITICAL NOTICES:

1. Standardization: Rosavin and Salidroside content may vary by product. Always verify 3% Rosavin / 1% Salidroside standardization.

2. Moisture Sensitivity: Botanical extracts are sensitive to moisture. High humidity may cause caking and degradation. Store in moisture-proof packaging.

3. Light Sensitivity: Active compounds are light-sensitive. Store in light-proof packaging.

4. Dosage Caution: High doses may cause nausea, dizziness, and sleep disturbances. Use within recommended dosage range.

5. Onset of Action: Adaptogenic effects typically appear after 2-4 weeks of regular use. Immediate effects should not be expected.

6. Drug Interactions: May interact with antidepressants, anxiolytics, and blood pressure medications. Consult your physician before use.

7. Timing: Recommended to take in the morning or afternoon; avoid evening use due to potential effects on sleep.

BEST PRACTICE RECOMMENDATIONS:

Storage:

• Store in a cool, dry, light-protected environment

• Use light-proof, moisture-proof packaging

• Store at room temperature (15-25°C)

• Reseal tightly after opening

Formulation:

• Can be used in capsules, tablets, or powder formulations

• Partially soluble in water and ethanol

• Can be combined with other adaptogens (Ashwagandha, Panax Ginseng)

• Combination with B vitamins and Vitamin C for synergistic effects

Handling:

• Use dust mask, protective goggles, and gloves

• Avoid dust formation

• Use in well-ventilated areas

• Wash hands after handling

Dosage:

• Daily dose: 200-600 mg (standardized extract)

• Recommended to take in the morning or afternoon

• Medical conditions require physician consultation

Waste Management:

• Dispose in accordance with local regulations

• Avoid release into the environment

LEGAL DISCLAIMER

This Technical Data Sheet (TDS) is for informational purposes only and is prepared based on available technical data. The user is solely responsible for determining the suitability of the product for their specific application and for complying with all local, national, and international regulations. For complete safety, storage, handling, transport, waste, and regulatory compliance information, the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier must be consulted. This document does not substitute professional advice. Dosage and application conditions should be optimized through product-specific trials. Regulatory status of Rhodiola Rosea extract may vary by country; verify compliance before use. Medical conditions require consultation with a healthcare professional.