Do you have questions? Let's talk! Get in Contact
info@betakim.com.tr

Allulose, D-Psicose, Psicose, D-Allulose, D-Erythro-hexulose, 551-68-8

Allulose, D-Psicose, Psicose, D-Allulose, D-Erythro-hexulose, 551-68-8

 

ALLULOSE (D-PSICOSE)

1. PRODUCT IDENTIFICATION AND CHEMICAL IDENTITY

Parameter Information
Product Name Allulose
Chemical Name D-Psicose
CAS Number 551-68-8
Molecular Formula C₆H₁₂O₆
Molecular Weight 180.16 g/mol
Chemical Class Monosaccharide (Rare sugar / Ketose)
E Number Not assigned (Novel food ingredient)
Appearance White crystalline powder
Odor Odorless
Taste Similar to sucrose, mildly sweet
Physical State (20°C) Solid (crystalline powder)

2. CHEMICAL STRUCTURE

2.1. Molecular Structure

Allulose (D-psicose) is a monosaccharide and a ketohexose. It is a C-3 epimer of fructose, meaning the hydroxyl group at the third carbon is in a different spatial arrangement. This structural difference is what gives allulose its unique properties, including its extremely low caloric value and reduced sweetness compared to sucrose.

Structural Formula:

        CH₂OH
         |
         C = O
         |
    H — C — OH
         |
    H — C — OH
         |
    HO — C — H
         |
        CH₂OH

Chemical Structure Properties:

Property Description
Classification Ketohexose (Monosaccharide)
Epimer of Fructose (C-3 epimer)
Functional Groups 1 ketone group (C=O), 5 hydroxyl groups (-OH)
Chirality 4 chiral centers
Optical Rotation [α]D20 = -16.3° (c = 1.0 in water)
Cyclic Forms Exists as furanose and pyranose ring forms in solution

2.2. Structural Comparison

Sugar Chemical Name Sweetness (vs Sucrose) Calories (kcal/g)
Allulose D-Psicose ~70% ~0.2
Fructose D-Fructose ~120% ~4.0
Sucrose Table sugar 100% ~4.0
Glucose D-Glucose ~70% ~4.0
Erythritol Sugar alcohol ~70% ~0.2

3. PHYSICAL AND CHEMICAL PROPERTIES

Property Value / Description
Appearance White crystalline powder
Odor Odorless
Taste Similar to sucrose, mildly sweet
Molecular Formula C₆H₁₂O₆
Molecular Weight 180.16 g/mol
Melting Point 109 – 112 °C (decomposes)
Density ~1.6 g/cm³
Solubility in Water (25°C) ~700 g/L (Very high solubility)
Solubility in Ethanol Slightly soluble
Sweetness Intensity ~70% of sucrose (0.7x)
Caloric Value ~0.2 kcal/g (approx. 5% of sucrose)
Glycemic Index 0 (Does not raise blood glucose)
pH (1% solution) 5.0 – 7.0
Optical Rotation [α]D20 = -16.3° (c = 1.0 in water)
Bulk Density ~600 – 800 kg/m³
Moisture Content ≤ 1.0%
Ash Content ≤ 0.1%

4. PHYSIOLOGICAL AND METABOLIC PROPERTIES

Parameter Information
Caloric Value ~0.2 kcal/g (compared to 4 kcal/g for sucrose)
Glycemic Index 0 (Does not raise blood sugar)
Insulin Response No significant insulin response
Metabolic Pathway Mostly excreted unchanged in urine
Digestibility Poorly metabolized; does not contribute to dental caries
Prebiotic Effect Some studies suggest potential prebiotic benefits
Safety Generally recognized as safe (GRAS) by FDA
Daily Intake Well tolerated up to ~30-40 g/day

5. FUNCTIONAL PROPERTIES

5.1. Sweetness Profile

Parameter Sucrose Allulose
Sweetness 100% (Reference) ~70% of sucrose
Sweetness Onset Fast Fast
Sweetness Duration Medium Short
Aftertaste Neutral Clean, no bitter aftertaste
Synergy - Synergistic with high-intensity sweeteners

5.2. Bulking and Texture Properties

Property Description
Bulk Density 600 – 800 kg/m³
Water Binding Capacity High
Hygroscopicity Moderate (less than fructose)
Freezing Point Depression Similar to sucrose
Boiling Point Elevation Similar to sucrose

5.3. Thermal Stability

Parameter Information
Maillard Reaction More reactive than sucrose; provides browning
Caramelization Begins at ~160°C
Thermal Degradation Begins above 120°C
Acid Stability Relatively stable at acidic pH

6. APPLICATION AREAS

6.1. Food and Beverage Industry

Application Function Details
Sugar Replacement Bulking and sweetening Replaces sucrose in reduced-calorie formulations
Beverages Sweetener Carbonated and non-carbonated drinks; enhances mouthfeel
Baked Goods Browning and texture Provides color through Maillard reaction; retains moisture
Confectionery Sweetening Hard candies, chocolates, caramels
Dairy Products Sweetening and bulking Ice cream, yogurt, flavored milk
Dressings and Sauces Flavor modification Reduces calories while maintaining taste
Jams and Preserves Bulking Low-sugar preserves
Nutritional Bars Binding and sweetening Protein bars, nutrition bars
Tabletop Sweeteners Sugar substitute Sachets, bulk sweeteners

6.2. Pharmaceutical and Nutraceutical Applications

Application Function Details
Oral Solutions Sweetening Pediatric formulations
Chewable Tablets Bulking agent Sugar-free formulations
Nutritional Supplements Low-calorie sweetener Protein powders, meal replacements
Diabetic Formulations Sugar-free Safe for diabetic patients

6.3. Sports Nutrition

Application Function Details
Sports Drinks Sweetening and energy Low glycemic index
Protein Powders Flavor enhancement Clean taste profile
Energy Gels Sweetening Low-calorie energy gels
Recovery Drinks Flavor improvement No insulin spike

6.4. Other Applications

Application Function Details
Oral Care Products Sweetener Non-cariogenic; toothpaste, mouthwash
Chewing Gum Sweetening Sugar-free gum
Medicinal Syrups Sweetening Cough syrups
Vegan Products Natural sweetener Plant-based formulations

7. TYPICAL USAGE LEVELS BY APPLICATION

Application Typical Usage Level Note
Beverages 1 – 10% Based on total formulation weight
Baked Goods 5 – 30% Flour weight basis
Confectionery 10 – 50% Formula dependent
Dairy Products 2 – 15% Total weight basis
Tabletop Sweeteners 100% Pure allulose or blended
Nutritional Bars 5 – 20% Formula dependent
Dressings and Sauces 1 – 5% Total weight basis
Jams and Preserves 20 – 50% Solids basis

8. DOSAGE AND FORMULATION GUIDELINES

8.1. Sweetness Substitution

Allulose has approximately 70% the sweetness of sucrose. For taste and texture matching:

Sugar Type Conversion Factor
Sucrose to Allulose 1.0 g sucrose = 1.43 g allulose
Fructose to Allulose 1.0 g fructose = 1.71 g allulose
Glucose to Allulose 1.0 g glucose = 1.00 g allulose (approx.)
Erythritol to Allulose 1.0 g erythritol = 1.00 g allulose (approx.)

8.2. Important Formulation Considerations

Consideration Recommendation
Sweetness Adjust for 70% sweetness intensity
Bulking Add dietary fibers or polydextrose to replace lost bulk
Browning Increased Maillard reaction; adjust baking time/temperature
Moisture Retention Higher moisture retention; may require reformulation
Crystallization Similar to sucrose; may crystallize in certain formulations

9. REGULATORY STATUS

Region / Authority Status
USA (FDA) GRAS (Generally Recognized as Safe); GRN 400, GRN 469, GRN 498, GRN 528
European Union Novel food approved; EFSA positive opinion
Japan Approved as food ingredient
Korea Approved as food ingredient
Australia/New Zealand Novel food approval
Turkey Approved for use in food products
Canada Approved as novel food
Mexico Approved
Singapore Approved

10. QUALITY SPECIFICATIONS (TYPICAL)

Parameter Specification Unit
Purity (Dry Basis) ≥ 98.0 – 99.5 %
Loss on Drying ≤ 1.0 %
Residue on Ignition (Ash) ≤ 0.1 %
pH (10% solution) 5.0 – 7.0 -
Specific Rotation [α]D20 -16.3° ± 1° -
Heavy Metals (as Pb) ≤ 10 ppm
Lead (Pb) ≤ 2.0 ppm
Arsenic (As) ≤ 1.0 ppm
Total Plate Count ≤ 1000 CFU/g
Yeast and Mold ≤ 100 CFU/g
Salmonella Negative -
E. coli Negative -

11. TOXICOLOGICAL PROFILE

Parameter Value
Acute Oral Toxicity (LD50, Rat) > 2,000 mg/kg (low toxicity)
Skin Irritation Not an irritant
Eye Irritation Not an irritant
Inhalation Dust may cause respiratory irritation
Carcinogenicity Not classified as a carcinogen
Mutagenicity Not mutagenic
Reproductive Toxicity No adverse effects observed
Gastrointestinal Tolerance Well tolerated up to 30-40 g/day; higher doses may cause GI discomfort
Allergenicity No known allergenic effects

12. GHS CLASSIFICATION

Hazard Class Category H-Statement
Not classified as hazardous

Signal Word: None

Hazard Pictograms: None

Hazard Statements: No H-codes

13. FIRST AID MEASURES

Route of Exposure Action to Be Taken
Inhalation Move to fresh air. If symptoms persist, seek medical attention
Skin Contact Wash with plenty of soap and water
Eye Contact Rinse thoroughly with plenty of water for at least 15 minutes. If irritation persists, seek medical attention
Ingestion Rinse mouth. Drink plenty of water. If large amount is swallowed, seek medical attention

14. STORAGE AND SHELF LIFE

Parameter Information
Storage Conditions Store in a cool, dry, well-ventilated area away from direct sunlight and moisture
Container Requirements Keep tightly closed in original packaging
Protect From Moisture, high humidity, strong odors
Shelf Life 24 months in unopened original packaging under proper storage conditions
After Opening Reseal tightly and protect from moisture

15. PACKAGING OPTIONS

Packaging Type Quantity Material
Kraft Bag 25 kg PE-lined kraft paper bag
Fiber Drum 25 kg, 50 kg PE-lined fiber drum
Big-Bag 500 kg, 1000 kg PE-lined PP woven bag
Small Containers 1 kg, 5 kg, 10 kg HDPE containers
Custom Packaging Upon request Various options available

16. TRANSPORT INFORMATION

Parameter Information
UN Number Not applicable (not dangerous goods)
Hazard Class Not applicable
Packing Group Not applicable
ADR/RID Not regulated
IMDG Not regulated
IATA Not regulated
Transport Temperature Ambient; protect from moisture and heat

17. ENVIRONMENTAL INFORMATION

Parameter Information
Biodegradability Readily biodegradable
Aquatic Toxicity Low toxicity
Bioaccumulation Not expected
Environmental Precautions Prevent large releases into water bodies

18. OTHER NAMES AND SYNONYMS

  • D-Psicose

  • Psicose

  • D-Allulose

  • Allulose (common name)

  • D-Erythro-hexulose

  • C-3 Epimer of Fructose

  • D-Ribo-2-hexulose

19. COMPARISON WITH OTHER SWEETENERS

Property Allulose Erythritol Stevia Monk Fruit Sucrose
Calories (kcal/g) 0.2 0.2 0 0 4.0
Sweetness (vs Sucrose) 70% 70% 200-300x 150-200x 100%
Glycemic Index 0 1 0 0 65
Dental Cavities No No No No Yes
Bulk Yes Yes No No Yes
Browning Yes No No No Yes
Taste Profile Clean Clean Bitter aftertaste Fruity Neutral
GI Tolerance Good (30-40g) Good (30-50g) Excellent Excellent Excellent
FDA Status GRAS GRAS GRAS GRAS GRAS

20. QUICK REFERENCE TABLE

Property Value
CAS Number 551-68-8
Molecular Formula C₆H₁₂O₆
Molecular Weight 180.16 g/mol
Appearance White crystalline powder
Melting Point 109-112 °C
Sweetness 70% of sucrose
Calories 0.2 kcal/g
Solubility ~700 g/L in water (25°C)
Shelf Life 24 months
Glycemic Index 0
FDA Status GRAS
GHS Signal Word None
UN Number Not applicable

21. CRITICAL NOTICES AND BEST PRACTICES

CRITICAL NOTICES:

  1. Sweetness Level: Allulose is only 70% as sweet as sucrose. Adjust usage levels accordingly to achieve desired sweetness.

  2. Browning Reactions: Allulose participates more readily in Maillard reactions than sucrose. Adjust baking times and temperatures to prevent over-browning.

  3. Moisture Retention: Allulose has high moisture retention properties. Formulations may need adjustment to account for increased moisture.

  4. Gastrointestinal Tolerance: While well tolerated, consumption of large amounts (exceeding 30-40 g/day) may cause gastrointestinal discomfort in some individuals.

  5. Crystallization: Under certain conditions, allulose can crystallize similarly to sucrose. Formulation should account for this.

  6. Caloric Claims: While allulose has ~0.2 kcal/g, it is not zero-calorie. Caloric content should be accurately labeled.

  7. Regulatory Status: While GRAS in the US, check local regulatory status before use in other countries.

BEST PRACTICE RECOMMENDATIONS:

Formulation:

  • Use 1.43 g allulose to replace 1.0 g sucrose

  • Combine with high-intensity sweeteners for full sweetness recovery

  • Add bulking agents (fibers, polydextrose) to replace lost bulk

  • Adjust water content to account for moisture retention

Baking:

  • Reduce oven temperature by 5-10°C to prevent over-browning

  • Add leavening agents to compensate for lower sugar content

  • Consider adding humectants to manage moisture

Beverages:

  • Allulose dissolves easily; no special handling required

  • Works well with acidic beverages

  • Stable across a wide pH range

Storage:

  • Store in a cool, dry place

  • Protect from moisture and high humidity

  • Keep tightly sealed in original packaging

Handling:

  • Use in well-ventilated areas

  • Avoid dust formation

  • Use food-grade handling equipment

LEGAL DISCLAIMER

This Technical Data Sheet (TDS) is for informational purposes only and is prepared based on available technical data. The user is solely responsible for determining the suitability of the product for their specific application and for complying with all local, national, and international regulations. For complete safety, storage, handling, transport, waste, and regulatory compliance information, the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier must be consulted. This document does not substitute professional advice. Dosage and application conditions should be optimized through product-specific trials. Regulatory status may vary by country; verify compliance before use.

Do you have questions? Let us help!

Effective Business Solutions? — Get in Contact
Scroll