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Hydroxypropyl Methacrylate, 2-Hydroxypropyl Methacrylate, Propylene Glycol Monomethacrylate, HPMA, 2-HPMA, 27813-02-1

Hydroxypropyl Methacrylate, 2-Hydroxypropyl Methacrylate, Propylene Glycol Monomethacrylate, HPMA, 2-HPMA, 27813-02-1

2-HYDROXYPROPYL METHACRYLATE (2-HPMA) 

CAS Number: 27813-02-1
EC Number (EINECS): 248-666-3
Molecular Formula: C₇H₁₂O₃
Molecular Weight: 144.17 g/mol
Chemical Class: Methacrylate ester (functional monomer)

SECTION 1: PRODUCT IDENTIFICATION AND CHEMICAL IDENTITY

Parameter Description
Chemical Name (IUPAC) 2-Hydroxypropyl 2-methylprop-2-enoate
Other Names 2-HPMA, Hydroxypropyl Methacrylate, HPMA, Propylene glycol monomethacrylate, 2-Hydroxypropyl methacrylate
CAS Number 27813-02-1
EC Number (EINECS) 248-666-3
Molecular Formula C₇H₁₂O₃
Molecular Weight 144.17 g/mol
Chemical Class Methacrylate ester (functional monomer)
Structure CH₂=C(CH₃)-COO-CH₂-CH(OH)-CH₃
Appearance Clear, colorless liquid
Physical State Liquid
Odor Mild acrylic
Functional Groups Methacrylate (C=C), hydroxyl (-OH)
Purity ≥ 97.0%
Inhibitor 200 ± 20 ppm MEHQ

SECTION 2: PHYSICAL AND CHEMICAL PROPERTIES

Property Value / Range
Molecular Formula C₇H₁₂O₃
Molecular Weight 144.17 g/mol
Appearance Clear, colorless liquid
Odor Mild acrylic
Density (20°C) ~1.029 g/cm³
Boiling Point ~87°C (under reduced pressure)
Freezing Point -58°C
Flash Point ~104°C
Viscosity (20°C) ~8.9 mPa·s
Vapor Pressure (20°C) 0.05 mmHg
Purity ≥ 97.0%
Acid Content ≤ 0.2%
Water Content ≤ 0.15%
Color (APHA) ≤ 30
Inhibitor 200 ± 20 ppm MEHQ
Solubility in Water Slightly soluble
Solubility in Organic Solvents Soluble in most organic solvents

SECTION 3: CHEMICAL PROPERTIES AND REACTIONS

Property Description
Chemical Class Methacrylate ester (functional monomer)
Functional Groups Methacrylate (C=C), hydroxyl (-OH)
Reactivity High; readily polymerizes
Polymerization Free-radical polymerization (bulk, solution, emulsion)
Copolymerization Copolymerizes with (meth)acrylic acid and salts, amides, esters, acrylonitrile, maleic esters, vinyl acetate, vinyl chloride, styrene, butadiene
Hydroxyl Reactivity Enables further functionalization via esterification, etherification, isocyanate reactions
Hydrophobicity Cyclic hydrophobic group provides hydrophobic character
Thermal Decomposition > 200°C releases CO, CO₂, and irritant vapors
Hydrolysis Hydrolyzes in acidic/basic media to methacrylic acid and propylene glycol
Oxidation May form peroxides in air

3.1. Key Reactions

Reaction Type Description
Radical Polymerization Forms homopolymers and copolymers
Copolymerization With acrylates, methacrylates, styrene, vinyl acetate, butadiene
Hydroxyl Reactions Esterification, etherification, isocyanate reaction
Hydrolysis Methacrylic acid + Propylene glycol

SECTION 4: FUNCTIONAL PROPERTIES

Property Description
Chemical Resistance Provides good chemical resistance
Hydrolytic Stability Good hydrolytic stability
Hydrophobicity Hydrophobic character due to cyclic group
Flexibility Provides flexibility in polymers
Adhesion Good adhesion properties
Impact Resistance Provides good impact resistance
Weather Resistance Good weather resistance
Hydroxyl Functionality Enables crosslinking and further modification

SECTION 5: MAJOR APPLICATIONS AND END-USES

5.1. Coatings (Most Important Application)

Application Function Suitability
Automotive Coatings Co-monomer, crosslinker High
Architectural Coatings Co-monomer, crosslinker High
Industrial Coatings Co-monomer, crosslinker High
Maintenance Coatings Co-monomer, crosslinker High
Acrylic Resins Co-monomer High

5.2. Adhesives and Sealants

Application Function Suitability
Adhesives Co-monomer, adhesion promoter High
Sealants Co-monomer, crosslinker High
Vacuum Impregnation Adhesives Hydrophobic hydroxyl monomer High
Chemical Anchors Co-monomer for vinyl ester formulations High

5.3. Textiles

Application Function Suitability
Textile Finishes Co-monomer High
Textile Coatings Co-monomer High

5.4. Plastics and Polymers

Application Function Suitability
Acrylic Sheets Co-monomer High
Unsaturated Polyesters Co-monomer High
Vinyl Ester Formulations Co-monomer High
Acrylic Rollers Co-monomer for automotive components High

5.5. Specialty Applications

Application Function Suitability
Photoresists Photosensitive material High
Hygiene Products Polymer components High
Oil Production Additives Additives for petroleum production and transport High
Modifications Polymer modification High
Casting Aluminum Components Vacuum impregnation adhesives High

SECTION 6: INDUSTRY SUITABILITY MATRIX

Industry Suitability Explanation
Coatings High Automotive, architectural, industrial coatings
Adhesives High Sealants, chemical anchors, vacuum impregnation
Textiles High Textile finishes and coatings
Plastics High Acrylic sheets, unsaturated polyesters
Automotive High Acrylic rollers, coatings
Electronics High Photoresists
Oil & Gas High Production and transport additives
Cosmetics Not suitable Not used in cosmetics
Food Not suitable Not used as food additive

SECTION 7: OTHER NAMES AND IDENTIFIERS

Type Name / Description
IUPAC Name 2-Hydroxypropyl 2-methylprop-2-enoate
Commercial Names 2-HPMA, HPMA, Hydroxypropyl Methacrylate, Blemmer P, Photomer 2317
Synonyms Propylene glycol monomethacrylate, beta-Hydroxypropyl methacrylate, Methacrylic acid 2-hydroxypropyl ester
CAS Number 27813-02-1
EC Number 248-666-3
HS Code 29161400

SECTION 8: TOXICOLOGY AND HEALTH EFFECTS

Parameter Value / Description
GHS Classification Warning
Hazard Statements H315 (Causes skin irritation), H317 (May cause allergic skin reaction), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation)
Precautionary Statements P261 (Avoid breathing dust/fume/gas/mist/vapors/spray), P280 (Wear protective gloves/protective clothing/eye protection/face protection), P302+P352 (IF ON SKIN: Wash with plenty of water), P305+P351+P338 (IF IN EYES: Rinse cautiously with water)
Oral LD50 (Rat) > 2,000 mg/kg
Dermal LD50 (Rabbit) > 2,000 mg/kg
Skin Irritation Irritant
Eye Irritation Irritant
Skin Sensitization Positive (allergic contact dermatitis)
Mutagenicity Negative
Carcinogenicity Not classified
Target Organs Skin, eyes, respiratory system

SECTION 9: SAFETY AND STORAGE

Parameter Information
Storage Conditions Cool, dry, well-ventilated area
Temperature 15–25°C (store under inert atmosphere)
Container Tightly closed, dark, stainless steel or HDPE containers
Special Requirements Must contain inhibitor (MEHQ); avoid extreme temperatures
Sunlight Protection Protect from direct sunlight
Moisture Sensitivity Protect from moisture
Shelf Life 12 months (under recommended conditions)
Packaging 200 kg drum, 1000 kg IBC

SECTION 10: TRANSPORT INFORMATION

Parameter Information
UN Number Not regulated (not classified as dangerous goods)
Hazard Class Not applicable
Packing Group Not applicable
Proper Shipping Name 2-Hydroxypropyl Methacrylate
ADR/RID Not regulated
IMDG Code Not regulated
IATA (Air) Not regulated
Marine Pollutant No

SECTION 11: FIRE-FIGHTING MEASURES

Parameter Information
Fire Hazard Combustible liquid (flash point ~104°C)
Extinguishing Media Water fog, foam, CO₂, dry chemical
Special Hazards When heated, releases CO, CO₂, and irritant vapors
Decomposition Products CO, CO₂, methacrylate vapors
Protective Equipment Self-contained breathing apparatus (SCBA), full protective clothing
Explosion Risk Vapor/air mixtures may be explosive at high temperatures

SECTION 12: ACCIDENTAL RELEASE AND CLEANUP

Parameter Information
Personal Protection Gloves, safety goggles, face shield, protective clothing
Ventilation Increase ventilation; evacuate area
Cleanup Methods Absorb with inert absorbent material; collect in sealed containers
Environmental Precautions Prevent entry into drains and water bodies
Waste Disposal According to local regulations; incineration (hazardous waste)

SECTION 13: FIRST AID MEASURES

Exposure Route Action
Inhalation Move to fresh air. Administer oxygen if breathing difficulty. Seek medical attention.
Skin Contact Remove contaminated clothing. Wash with soap and plenty of water for at least 15 minutes. Seek medical attention.
Eye Contact Rinse with plenty of water for at least 15 minutes. Seek medical attention.
Ingestion Do NOT induce vomiting. Drink plenty of water. Seek medical attention.

SECTION 14: REGULATORY INFORMATION

Region / Authority Status
EU REACH Registered
Turkey KKDİK Registration required
USA TSCA Listed
EINECS 248-666-3
WGK (Germany) 1 (slight hazard to water)
RoHS Compliant
California Prop 65 Not listed

SECTION 15: SUMMARY AND CRITICAL WARNINGS

Product Summary

Parameter Value
Product 2-Hydroxypropyl Methacrylate (2-HPMA)
CAS 27813-02-1
Appearance Clear, colorless liquid
Density ~1.029 g/cm³
Boiling Point ~87°C
Flash Point ~104°C
Key Industries Coatings, adhesives, textiles, plastics, automotive

CRITICAL WARNINGS

  1. Functional Monomer: 2-HPMA is a functional hydrophobic-hydroxyl monomer containing both methacrylate and hydroxyl groups. The cyclic hydrophobic group provides unique properties.

  2. Hydrophobic-Hydroxyl Balance: The combination of hydrophobic character and hydroxyl functionality enables versatile applications requiring both properties.

  3. Hydroxyl Reactivity: The hydroxyl group enables further chemical reactions such as esterification, etherification, and isocyanate reactions. This enables crosslinking and polymer modification.

  4. Versatile Copolymerization: Copolymerizes with (meth)acrylic acid and salts, amides, esters, acrylonitrile, maleic esters, vinyl acetate, vinyl chloride, styrene, butadiene, and other monomers.

  5. Polymerization Risk: Readily polymerizes; always contains inhibitor (MEHQ). Keep away from heat and light.

  6. Skin Sensitizer: 2-HPMA may cause allergic skin reactions (H317). Appropriate PPE required.

  7. Chemical Resistance: Provides good chemical resistance and hydrolytic stability.

  8. Storage: Store in cool, dark, well-ventilated areas under inert atmosphere. Shelf life is 12 months.

  9. Versatile Applications: Used in automotive coatings, architectural coatings, industrial coatings, textiles, adhesives, plastics, photoresists, and oil production additives.

  10. Regulatory Status: Registered under REACH. Not classified as dangerous goods.

IMPORTANT DISCLAIMER: This Technical Data Sheet (TDS) is for informational purposes only and is based on available technical data. The user is solely responsible for determining the product's suitability for their specific application and for complying with all applicable local, national, and international regulations. 2-HPMA readily polymerizes and is a known skin sensitizer! For complete safety, storage, handling, transportation, disposal, and regulatory compliance information, always refer to the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier. Users are responsible for testing the product in their own processes and applications. All local, national, and international regulations must be followed when working with 2-HPMA.

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