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Glycidyl Methacrylate, Glycidol Methacrylate, GMA, 106-91-2

Glycidyl Methacrylate, Glycidol Methacrylate, GMA, 106-91-2

GLYCIDYL METHACRYLATE (GMA) 

CAS Number: 106-91-2
EC Number (EINECS): 203-441-9
Molecular Formula: C₇H₁₀O₃
Molecular Weight: 142.15 g/mol
Chemical Class: Methacrylate ester (functional monomer)

SECTION 1: PRODUCT IDENTIFICATION AND CHEMICAL IDENTITY

Parameter Description
Chemical Name (IUPAC) Oxiran-2-ylmethyl 2-methylprop-2-enoate
Other Names GMA, Glycidyl Methacrylate, 2,3-Epoxypropyl methacrylate, Glycidol methacrylate, Methacrylic Acid Glycidyl Ester
CAS Number 106-91-2
EC Number (EINECS) 203-441-9
Molecular Formula C₇H₁₀O₃
Molecular Weight 142.15 g/mol
Chemical Class Methacrylate ester (functional monomer)
Structure CH₂=C(CH₃)-COO-CH₂-(C₂H₃O)
Appearance Clear, colorless liquid
Physical State Liquid
Odor Fruity
Functional Groups Methacrylate (C=C), epoxy (oxirane)
Purity ≥ 98.5%
Inhibitor 100 ± 10 ppm MEHQ

SECTION 2: PHYSICAL AND CHEMICAL PROPERTIES

Property Value / Range
Molecular Formula C₇H₁₀O₃
Molecular Weight 142.15 g/mol
Appearance Clear, colorless liquid
Odor Fruity
Density (20°C) 1.073–1.083 g/cm³
Boiling Point ~189°C
Freezing Point -41.5°C
Flash Point ~76°C
Viscosity (25°C) ~2.14 mPa·s
Vapor Pressure (75°C) 1,333 Pa (10 mmHg)
Purity ≥ 98.5%
Acid Content ≤ 0.5%
Water Content ≤ 0.1%
Color (APHA) ≤ 30
Inhibitor 100 ± 10 ppm MEHQ

SECTION 3: CHEMICAL PROPERTIES AND REACTIONS

Property Description
Chemical Class Methacrylate ester (functional monomer)
Functional Groups Methacrylate (C=C), epoxy (oxirane)
Reactivity Very high; dual functionality with methacrylate and epoxy groups
Polymerization Free-radical polymerization (methacrylate group)
Epoxy Reactions Crosslinking, curing, functionalization via epoxy group
Copolymerization Copolymerizes with acrylates, methacrylates, styrene, vinyl acetate
Thermal Decomposition > 200°C releases CO, CO₂, and irritant vapors
Hydrolysis Hydrolyzes in acidic/basic media to methacrylic acid and glycidol
Oxidation May form peroxides in air

3.1. Key Reactions

Reaction Type Description
Radical Polymerization Forms poly(glycidyl methacrylate)
Copolymerization With acrylates, methacrylates, styrene, vinyl acetate
Epoxide Ring Opening Reacts with acids, alcohols, amines
Crosslinking Forms crosslinked networks via epoxy group
Functionalization Further functionalization via epoxy group

SECTION 4: FUNCTIONAL PROPERTIES

Property Description
Dual Functionality Versatile reactivity with methacrylate and epoxy groups
Adhesion Provides excellent adhesion between different materials
Crosslinking Enables crosslinking in polymer systems
Versatility Suitable for a wide range of applications
Reactivity High polymerization and epoxy reactivity
Heat Resistance Good thermal stability

SECTION 5: MAJOR APPLICATIONS AND END-USES

5.1. Coatings and Resins (Most Important Application)

Application Function Suitability
Industrial Protective Coatings Co-monomer, crosslinker High
Varnishes and Paints Quality enhancer, crosslinker High
Powder Coatings Crosslinker High
UV Curable Coatings Reactive monomer High

5.2. Adhesives

Application Function Suitability
Adhesives Adhesion promoter, crosslinker High
Structural Adhesives Crosslinker High

5.3. Polymer Modification

Application Function Suitability
Thermoplastic Modification Functional monomer High
Ion Exchange Resins Functional monomer High
Synthetic Fibers Performance enhancer High
Natural Rubber Quality enhancer High

5.4. Textiles

Application Function Suitability
Textile Finishes Crosslinker High
Latex Industrial protective coatings High

5.5. Electronics and Microelectronics

Application Function Suitability
Radio Engineering Electrical resistance, coatings High
Microelectronics Electrical applications High
Electrical Resistance Modification High

5.6. Biotechnology and Medical

Application Function Suitability
Biotechnology Biocompatible polymers High
Medical Applications Medical devices, biomaterials High
Dental Materials Composite resins High

5.7. Automotive

Application Function Suitability
Automotive Coatings Crosslinker High
Automotive Adhesives Adhesion promoter High

5.8. Graphic Arts and Printing

Application Function Suitability
Graphic Arts Printing materials High

SECTION 6: INDUSTRY SUITABILITY MATRIX

Industry Suitability Explanation
Coatings High Industrial coatings, varnishes, paints
Adhesives High Structural adhesives
Polymer Modification High Thermoplastics, ion exchange resins
Textiles High Textile finishes, latex
Electronics High Microelectronics, radio engineering
Biotechnology / Medical High Biocompatible polymers, dental materials
Automotive High Coatings, adhesives
Graphic Arts High Printing materials
Cosmetics Not suitable Not used in cosmetics
Food Not suitable Not used as food additive

SECTION 7: OTHER NAMES AND IDENTIFIERS

Type Name / Description
IUPAC Name Oxiran-2-ylmethyl 2-methylprop-2-enoate
Commercial Names GMA, Glycidyl Methacrylate, SY-Monomer G, Blemmer G, Light Ester G
Synonyms 2,3-Epoxypropyl methacrylate, Methacrylic Acid Glycidyl Ester, Glycidol methacrylate
CAS Number 106-91-2
EC Number 203-441-9
HS Code 29161400

SECTION 8: TOXICOLOGY AND HEALTH EFFECTS

Parameter Value / Description
GHS Classification Warning
Signal Word Warning
Hazard Statements H315 (Causes skin irritation), H317 (May cause allergic skin reaction), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation), H341 (Suspected of causing genetic defects)
Precautionary Statements P201 (Obtain special instructions before use), P261 (Avoid breathing dust/fume/gas/mist/vapors/spray), P280 (Wear protective gloves/protective clothing/eye protection/face protection), P302+P352 (IF ON SKIN: Wash with plenty of water), P305+P351+P338 (IF IN EYES: Rinse cautiously with water)
Oral LD50 (Rat) ~1,000-2,000 mg/kg
Dermal LD50 (Rabbit) > 2,000 mg/kg
Skin Irritation Irritant
Eye Irritation Irritant
Skin Sensitization Positive (allergic contact dermatitis)
Mutagenicity Suspected (H341)
Carcinogenicity Not classified
Target Organs Skin, eyes, respiratory system

SECTION 9: SAFETY AND STORAGE

Parameter Information
Storage Conditions Cool, dry, well-ventilated area
Temperature 15–25°C (store under inert atmosphere)
Container Tightly closed, dark, stainless steel or HDPE containers
Special Requirements Must contain inhibitor (MEHQ); avoid extreme temperatures
Sunlight Protection Protect from direct sunlight
Moisture Sensitivity Sensitive to moisture (epoxy ring)
Shelf Life 12 months (under recommended conditions)
Packaging 25 kg bag, 200 kg drum, 1000 kg IBC

SECTION 10: TRANSPORT INFORMATION

Parameter Information
UN Number Not regulated (not classified as dangerous goods)
Hazard Class Not applicable
Packing Group Not applicable
Proper Shipping Name Glycidyl Methacrylate
ADR/RID Not regulated
IMDG Code Not regulated
IATA (Air) Not regulated
Marine Pollutant No

SECTION 11: FIRE-FIGHTING MEASURES

Parameter Information
Fire Hazard Combustible liquid (flash point ~76°C)
Extinguishing Media Water fog, foam, CO₂, dry chemical
Special Hazards When heated, releases CO, CO₂, and irritant vapors
Decomposition Products CO, CO₂, epoxy and methacrylate vapors
Protective Equipment Self-contained breathing apparatus (SCBA), full protective clothing
Explosion Risk Vapor/air mixtures may be explosive at high temperatures

SECTION 12: ACCIDENTAL RELEASE AND CLEANUP

Parameter Information
Personal Protection Gloves, safety goggles, face shield, protective clothing
Ventilation Increase ventilation; evacuate area
Cleanup Methods Absorb with inert absorbent material; collect in sealed containers
Environmental Precautions Prevent entry into drains and water bodies
Waste Disposal According to local regulations; incineration (hazardous waste)

SECTION 13: FIRST AID MEASURES

Exposure Route Action
Inhalation Move to fresh air. Administer oxygen if breathing difficulty. Seek medical attention.
Skin Contact Remove contaminated clothing. Wash with soap and plenty of water for at least 15 minutes. Seek medical attention.
Eye Contact Rinse with plenty of water for at least 15 minutes. Seek immediate medical attention.
Ingestion Do NOT induce vomiting. Drink plenty of water. Seek immediate medical attention.

SECTION 14: REGULATORY INFORMATION

Region / Authority Status
EU REACH Registered
Turkey KKDİK Registration required
USA TSCA Listed
EINECS 203-441-9
WGK (Germany) 1 (slight hazard to water)
RoHS Compliant
California Prop 65 Not listed

SECTION 15: SUMMARY AND CRITICAL WARNINGS

Product Summary

Parameter Value
Product Glycidyl Methacrylate (GMA)
CAS 106-91-2
Appearance Clear, colorless liquid
Density ~1.078 g/cm³
Boiling Point ~189°C
Flash Point ~76°C
Key Industries Coatings, adhesives, polymer modification, electronics

CRITICAL WARNINGS

  1. Dual Functional Monomer: GMA is a dual-functional monomer containing both a polymerizable methacrylate group and an epoxy group for further reactions. This unique combination makes it highly versatile and reactive.

  2. Adhesion Promoter: GMA is an essential component in adhesives and coatings due to its ability to enhance adhesion between different materials.

  3. Epoxy Reactivity: The epoxy group enables crosslinking and functionalization reactions. This allows the formation of crosslinked networks in polymer systems.

  4. Polymerization Risk: Readily polymerizes; always contains inhibitor (MEHQ). Keep away from heat and light.

  5. Skin Sensitizer: GMA may cause allergic skin reactions (H317). Appropriate PPE required.

  6. Mutagenicity Suspect: GMA is suspected of causing genetic defects (H341). Handle with caution.

  7. Moisture Sensitivity: The epoxy ring is sensitive to moisture. Store in dry conditions.

  8. Storage: Store in cool, dark, well-ventilated areas. Shelf life is 12 months.

  9. Versatile Applications: Used in coatings, adhesives, textiles, electronics, biotechnology, automotive, and graphic arts.

  10. Regulatory Status: Registered under REACH. Not classified as dangerous goods but requires careful handling due to mutagenicity suspicion.

IMPORTANT DISCLAIMER: This Technical Data Sheet (TDS) is for informational purposes only and is based on available technical data. The user is solely responsible for determining the product's suitability for their specific application and for complying with all applicable local, national, and international regulations. GMA readily polymerizes, is a known skin sensitizer, and is suspected of causing genetic defects! For complete safety, storage, handling, transportation, disposal, and regulatory compliance information, always refer to the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier. Users are responsible for testing the product in their own processes and applications. All local, national, and international regulations must be followed when working with GMA.

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