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Methylolacrylamide, N-Methylolacrylamide, NMA, 924-42-5

Methylolacrylamide, N-Methylolacrylamide, NMA, 924-42-5

N-METHYLOL ACRYLAMIDE (NMA48) 

CAS Number: 924-42-5
EC Number (EINECS): 213-103-2
Molecular Formula: C₄H₇NO₂
Molecular Weight: 101.10 g/mol
Chemical Class: Acrylamide derivative (functional monomer)

SECTION 1: PRODUCT IDENTIFICATION AND CHEMICAL IDENTITY

Parameter Description
Chemical Name (IUPAC) N-(Hydroxymethyl)prop-2-enamide
Other Names NMA, N-Methylolacrylamide, Methylolacrylamide, N-Hydroxymethyl acrylamide, Uramin T 80
CAS Number 924-42-5
EC Number (EINECS) 213-103-2
Molecular Formula C₄H₇NO₂
Molecular Weight 101.10 g/mol
Chemical Class Acrylamide derivative (functional monomer)
Structure CH₂=CH-C(=O)-NH-CH₂OH
Appearance Colorless to pale yellow liquid
Physical State Liquid
Odor Ester-like
Active Content 40–44%
Functional Groups Vinyl (C=C), amide, hydroxyl (-OH)

SECTION 2: PHYSICAL AND CHEMICAL PROPERTIES

Property Value / Range
Molecular Formula C₄H₇NO₂
Molecular Weight 101.10 g/mol
Appearance Colorless to pale yellow liquid
Odor Ester-like
Active Content 40–44%
Boiling Point ~277°C
Freezing Point ~75°C
Vapor Pressure (25°C) 0.03 Pa
Solubility in Water Soluble
Solubility in Organic Solvents Soluble
Polymerization Inhibitor MEHQ (typically)

SECTION 3: CHEMICAL PROPERTIES AND REACTIONS

Property Description
Chemical Class Acrylamide derivative (functional monomer)
Functional Groups Vinyl (C=C), amide, hydroxyl (-OH)
Reactivity High; readily polymerizes and crosslinks
Crosslinking Self-crosslinks via hydroxymethyl groups or with other reactive groups
Polymerization Free-radical polymerization (solution, emulsion)
Copolymerization Copolymerizes with acrylates, methacrylates, styrene, vinyl acetate
Thermal Decomposition > 200°C releases nitrogen oxides (NOₓ), CO, CO₂
Hydrolysis Hydrolyzes in acidic/basic media
Oxidation Stable under normal conditions

3.1. Key Reactions

Reaction Type Description
Radical Polymerization Forms crosslinkable polymers
Copolymerization With acrylates, methacrylates, styrene, vinyl acetate
Self-Crosslinking Forms bonds between hydroxymethyl groups
Condensation Crosslinks under heat or acid catalysis

SECTION 4: FUNCTIONAL PROPERTIES

Property Description
Crosslinking Forms strong crosslinks in polymer systems
Adhesion Provides enhanced adhesion
Mechanical Strength Increases mechanical durability
Durability Enhances final product durability
Water Solubility High water solubility
Reactivity High polymerization and crosslinking reactivity

SECTION 5: MAJOR APPLICATIONS AND END-USES

5.1. Textile Industry (Most Important Application)

Application Function Suitability
Textile Finishing Agents Crosslinker High
Fabric Coatings Durability enhancer High
Nonwoven Binders Binder High

5.2. Adhesives and Binders

Application Function Suitability
Adhesives Crosslinker, adhesion enhancer High
Binders Polymeric binder High

5.3. Coatings and Paints

Application Function Suitability
Coatings Crosslinker, film former High
Paints Crosslinker High
Varnishes Crosslinker High

5.4. Polymerization and Resins

Application Function Suitability
Polymerization As monomer High
Resins Crosslinker High

5.5. Water Treatment

Application Function Suitability
Water Treatment Polymeric flocculants High

5.6. Personal Care and Cosmetics

Application Function Suitability
Personal Care Products Polymer components High
Cosmetics Formulation components High

5.7. Paper Industry

Application Function Suitability
Paper Strengtheners Strength enhancer High

SECTION 6: INDUSTRY SUITABILITY MATRIX

Industry Suitability Explanation
Textiles High Finishing agents, coatings, binders
Adhesives High Crosslinker, adhesion enhancer
Coatings High Crosslinker, film former
Polymers High Monomer, crosslinker
Water Treatment High Flocculants
Paper High Strengtheners
Personal Care High Polymer components
Cosmetics High Formulation components
Food Not suitable Not used as direct food additive

SECTION 7: OTHER NAMES AND IDENTIFIERS

Type Name / Description
IUPAC Name N-(Hydroxymethyl)prop-2-enamide
Commercial Names NMA, N-Methylolacrylamide, Uramin T 80
Synonyms N-Methylol Acrylamide, N-Hydroxymethyl acrylamide, Methylolacrylamide, N-Methanolacrylamide
CAS Number 924-42-5
EC Number 213-103-2
HS Code 29241900

SECTION 8: TOXICOLOGY AND HEALTH EFFECTS

Parameter Value / Description
GHS Classification Warning
Hazard Statements H302 (Harmful if swallowed), H315 (Causes skin irritation), H317 (May cause allergic skin reaction), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation)
Precautionary Statements P261 (Avoid breathing dust/fume/gas/mist/vapors/spray), P280 (Wear protective gloves/protective clothing/eye protection/face protection), P302+P352 (IF ON SKIN: Wash with plenty of water), P305+P351+P338 (IF IN EYES: Rinse cautiously with water)
Skin Irritation Irritant
Eye Irritation Irritant
Skin Sensitization Positive (allergic contact dermatitis)
Mutagenicity Suspect
Carcinogenicity IARC Group 3 (not classifiable)
Target Organs Skin, eyes, respiratory system

SECTION 9: SAFETY AND STORAGE

Parameter Information
Storage Conditions Cool, dry, well-ventilated area
Temperature 15–30°C (protect from freezing)
Container Tightly closed, original packaging (IBC, 1000 kg)
Freeze Protection Freezing point ~75°C; freezing risk is low
Sunlight Protection Protect from direct sunlight
Polymerization Risk Keep away from heat and light; contains inhibitor
Shelf Life 12 months (under recommended conditions)
Packaging 1000 kg IBC

SECTION 10: TRANSPORT INFORMATION

Parameter Information
UN Number Not regulated (not classified as dangerous goods)
Hazard Class Not applicable
Packing Group Not applicable
Proper Shipping Name N-Methylol Acrylamide Solution
ADR/RID Not regulated
IMDG Code Not regulated
IATA (Air) Not regulated
Marine Pollutant No

SECTION 11: FIRE-FIGHTING MEASURES

Parameter Information
Fire Hazard Combustible liquid
Extinguishing Media Water fog, foam, CO₂, dry chemical
Special Hazards When heated, releases nitrogen oxides (NOₓ), CO, CO₂
Decomposition Products Nitrogen oxides, CO, CO₂
Protective Equipment Self-contained breathing apparatus (SCBA), full protective clothing

SECTION 12: ACCIDENTAL RELEASE AND CLEANUP

Parameter Information
Personal Protection Gloves, safety goggles, face shield, protective clothing
Ventilation Increase ventilation
Cleanup Methods Absorb with inert absorbent material; collect in sealed containers
Environmental Precautions Prevent entry into drains and water bodies
Waste Disposal According to local regulations; incineration (hazardous waste)

SECTION 13: FIRST AID MEASURES

Exposure Route Action
Inhalation Move to fresh air. Administer oxygen if breathing difficulty. Seek medical attention.
Skin Contact Remove contaminated clothing. Wash with soap and plenty of water for at least 15 minutes. Seek medical attention.
Eye Contact Rinse with plenty of water for at least 15 minutes. Seek medical attention.
Ingestion Do NOT induce vomiting. Drink plenty of water. Seek medical attention.

SECTION 14: REGULATORY INFORMATION

Region / Authority Status
EU REACH Registered
Turkey KKDİK Registration required
USA TSCA Listed
IARC Group 3 (not classifiable)
EINECS 213-103-2
WGK (Germany) 1 (slight hazard to water)
RoHS Compliant
California Prop 65 Not listed

SECTION 15: SUMMARY AND CRITICAL WARNINGS

Product Summary

Parameter Value
Product N-Methylol Acrylamide (NMA48)
CAS 924-42-5
Appearance Colorless to pale yellow liquid
Active Content 40–44%
Molecular Weight 101.10 g/mol
Key Industries Textiles, adhesives, coatings, polymers

CRITICAL WARNINGS

  1. Functional Monomer: NMA is a methylolacrylamide monomer with unique crosslinking properties. The hydroxymethyl group enables crosslinking reactions.

  2. Crosslinking Ability: Forms strong crosslinks in polymer systems. This property plays a critical role in enhancing product performance in adhesives, coatings, and textiles.

  3. Aqueous Solution Form: The product is supplied as a 40–44% active aqueous solution. This form facilitates direct use in water-based systems.

  4. Polymerization Risk: Readily polymerizable; contains inhibitor. Keep away from heat and light.

  5. Skin Sensitizer: NMA may cause allergic skin reactions (H317). Appropriate PPE required.

  6. IARC Group 3: Classified by IARC as Group 3 (not classifiable as to carcinogenicity to humans).

  7. Storage: Store in cool, dry, well-ventilated areas. Freezing point ~75°C; freezing risk is low.

  8. Shelf Life: 12 months. Inhibitor levels should be checked during long-term storage to prevent polymerization.

  9. Versatile Applications: Used in textiles, adhesives, coatings, water treatment, personal care, paper, and polymer industries.

  10. Regulatory Status: Registered under REACH. Not classified as dangerous goods.

IMPORTANT DISCLAIMER: This Technical Data Sheet (TDS) is for informational purposes only and is based on available technical data. The user is solely responsible for determining the product's suitability for their specific application and for complying with all applicable local, national, and international regulations. NMA is readily polymerizable and is a known skin sensitizer! For complete safety, storage, handling, transportation, disposal, and regulatory compliance information, always refer to the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier. Users are responsible for testing the product in their own processes and applications. All local, national, and international regulations must be followed when working with NMA.

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