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L-Arginine Hydrochloride, L-Arginine HCL, 1119-34-2

L-Arginine Hydrochloride, L-Arginine HCL, 1119-34-2

Chemical Identity

  • Chemical Name: L-Arginine Hydrochloride

  • Molecular Formula: C₆H₁₄N₄O₂·HCl

  • Molecular Weight: 210.66 g/mol

  • CAS Number: 1119-34-2

  • IUPAC Name: (S)-2-amino-5-guanidinopentanoic acid hydrochloride

Physical Properties

  • Appearance: White crystalline powder

  • Solubility: Highly soluble in water (better than free base L-Arginine)

  • pH: Slightly acidic due to hydrochloride salt

  • Stability: More stable than free base form; longer shelf life

  • Storage: Keep sealed, dry, and away from heat; shelf life ~2 years

Functional Role

  • Nitric Oxide Precursor: Enhances vasodilation, blood flow, and oxygen delivery

  • Protein Metabolism: Incorporated into proteins as a coding amino acid

  • Hormonal Regulation: Stimulates pituitary gland to release growth hormone

  • Detoxification: Supports urea cycle, reducing ammonia levels in blood

Applications

Pharmaceutical / Medical

  • Used in formulations for cardiovascular support (blood pressure regulation, vascular health)

  • Intravenous testing of pituitary function (growth hormone release)

  • Wound healing and tissue regeneration

  • Supportive treatment in liver disorders and hyperammonemia

Sports Nutrition

  • Popular in pre-workout supplements for “pump” effect

  • Improves endurance and recovery by boosting nitric oxide synthesis

  • Often combined with creatine, BCAA, or citrulline

Food / Nutraceuticals

  • Added to functional foods, protein bars, and sports drinks

  • Immune-support supplements

Veterinary / Animal Nutrition

  • Amino acid source in specialized feed formulations

Research / Biotechnology

  • Used in cell culture media as a nitrogen source

  • Studied in nitric oxide pathway experiments

Commercial Formats

  • Pharma/Food Grade: 25 kg fiber drum or HDPE bag

  • Consumer Supplements: 300–500 g jars, capsules, tablets

  • Documentation: COA, TDS, GMP/ISO certificates required for compliance

Key Differences vs. L-Arginine (Base Form)

Property L-Arginine (CAS 74-79-3) L-Arginine HCl (CAS 1119-34-2)
Molecular Weight 174.20 g/mol 210.66 g/mol
Solubility Moderate in water High in water
Stability Less stable More stable
pH Strongly alkaline Slightly acidic
Common Use Medical, research Sports nutrition, food supplements

Images

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