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Gadolinium Acetate, Gadolinium Acetate Tetrahydrate, Gadolinium Acetate Hydrate, Gadolinium Acetate Anhydrous, 100587‑93‑7, 31298-16-5, 15280-53-2

Gadolinium Acetate, Gadolinium Acetate Tetrahydrate, Gadolinium Acetate Hydrate, Gadolinium Acetate Anhydrous, 100587‑93‑7, 31298-16-5, 15280-53-2

GADOLINIUM ACETATE (GADOLINIUM ACETATE / GADOLINIUM ACETATE TETRAHYDRATE)

PRODUCT IDENTIFICATION INFORMATION

Parameter Information
Product Name Gadolinium Acetate / Gadolinium Acetate
Other Technical Names Gadolinium Acetate Tetrahydrate, Gadolinium Acetate Hydrate, Gadolinium Acetate Anhydrous
CAS Numbers 31298-16-5 (Anhydrous); 15280-53-2 (Tetrahydrate); 100587-93-7 (Hydrate Variant)
Chemical Formula Gd(C₂H₃O₂)₃·4H₂O (Tetrahydrate); Gd(CH₃COO)₃ (Anhydrous)
Molecular Weight ~352.37 g/mol (Tetrahydrate); ~370.53 g/mol (Anhydrous)
EC Number (EINECS) 240-204-9
Product Family Rare Earth Acetate Salt
Appearance White crystalline solid (Tetrahydrate); White powder (Anhydrous)

CHEMICAL STRUCTURE

    Gadolinium Acetate Tetrahydrate [Gd(C₂H₃O₂)₃·4H₂O]
    
    Gadolinium Ions (Gd³⁺) and Acetate Ions (C₂H₃O₂⁻)
    in Tetrahydrate Form (with 4 H₂O Molecules)
    
         C₂H₃O₂⁻  Gd³⁺  C₂H₃O₂⁻
           \         |         /
            C₂H₃O₂⁻-Gd³⁺-C₂H₃O₂⁻
           /         |         \
         C₂H₃O₂⁻  Gd³⁺  C₂H₃O₂⁻
    
    Gadolinium Ions (Gd³⁺) with Acetate Ions (C₂H₃O₂⁻)
    Surrounded by 4 Water Molecules (H₂O)
    Rare Earth Acetate Salt
    White Crystalline Solid
    Used in Catalyst and Optical Applications

Molecular Formula: Gd(C₂H₃O₂)₃·4H₂O (Tetrahydrate)
Ionic Structure: Gd³⁺ and C₂H₃O₂⁻ ions
Hydrate State: Tetrahydrate (4 water molecules) or Anhydrous
Color: White

SECTION 1: CHEMICAL IDENTITY AND DEFINITION

Parameter Information
Product Name Gadolinium Acetate / Gadolinium Acetate
Other Technical Names (English) Gadolinium Acetate Tetrahydrate, Gadolinium Acetate Hydrate, Gadolinium Acetate Anhydrous
Other Technical Names (Turkish) Gadolinyum Asetat, Gadolinyum Asetat Tetrahydrat, Gadolinyum Asetat Hidrat, Gadolinyum Asetat Susuz
Other Technical Names (German) Gadoliniumacetat, Gadoliniumacetat Tetrahydrat, Gadoliniumacetat Hydrat
Other Technical Names (French) Acétate de Gadolinium, Acétate de Gadolinium Tétrahydraté, Acétate de Gadolinium Hydraté
Other Technical Names (Spanish) Acetato de Gadolinio, Acetato de Gadolinio Tetrahidratado, Acetato de Gadolinio Hidratado
CAS Numbers 31298-16-5 (Anhydrous); 15280-53-2 (Tetrahydrate); 100587-93-7 (Hydrate Variant)
EC Number (EINECS) 240-204-9
Chemical Formula Gd(C₂H₃O₂)₃·4H₂O (Tetrahydrate); Gd(CH₃COO)₃ (Anhydrous)
Molecular Weight ~352.37 g/mol (Tetrahydrate); ~370.53 g/mol (Anhydrous)
Chemical Class Rare Earth Acetate Salt
Appearance White crystalline solid (Tetrahydrate); White powder (Anhydrous)
Odor Slight acetic acid odor
Color White
Crystal Structure Crystalline solid

SECTION 2: PHYSICAL AND CHEMICAL PROPERTIES

Property Tetrahydrate Anhydrous Note
Chemical Formula Gd(C₂H₃O₂)₃·4H₂O Gd(CH₃COO)₃ -
CAS Number 15280-53-2 31298-16-5 -
Appearance White crystalline solid White powder -
Molecular Weight ~352.37 g/mol ~370.53 g/mol -
Density ~2.5-2.7 g/cm³ ~2.5-2.7 g/cm³ -
Melting Point Decomposes upon heating Decomposes upon heating -
Solubility Soluble in water; Soluble in acetic acid Soluble in water; Soluble in acetic acid -
Hygroscopic Slightly hygroscopic Slightly hygroscopic Absorbs moisture
pH Neutral to slightly acidic Neutral to slightly acidic -
Stability Stable under normal conditions Stable under normal conditions -

SECTION 3: CHEMICAL PROPERTIES AND REACTIVITY

Parameter Information
Chemical Character Rare earth acetate salt; Derived from gadolinium element; MRI contrast agent; Catalyst; Optical materials
Stability Stable under normal conditions; Protect from moisture and light; Decomposes at high temperatures
Reactivity Soluble in water; Soluble in acetic acid; Reacts with strong bases and reducing agents
Incompatible Materials Strong bases, reducing agents, oxidizing agents, moisture
Thermal Decomposition Gd(C₂H₃O₂)₃·4H₂O → heat → Gd₂O₃ + CO₂ + H₂O (decomposes upon heating)
Solubility in Water Soluble in water; Dissociates into Gd³⁺ and C₂H₃O₂⁻ ions
Acid Solubility Soluble in acetic acid
Special Property Precursor for gadolinium oxide and other gadolinium compounds; MRI contrast agents; Catalysts; Optical materials

SECTION 4: GADOLINIUM ACETATE FORMS AND CAS NUMBERS

Type Chemical Formula CAS Number Explanation
Anhydrous Gd(CH₃COO)₃ 31298-16-5 Anhydrous form; Special synthesis in laboratories
Tetrahydrate Gd(C₂H₃O₂)₃·4H₂O 15280-53-2 Most common commercial form; White crystalline structure
Hydrate Variant Gd(C₂H₃O₂)₃·xH₂O 100587-93-7 Hydrated form; Sold as "trace metals basis"

SECTION 5: GADOLINIUM ACETATE GRADES

Grade Purity (%) Form Application Areas
GA-1 ≥ 99.99% Crystalline powder High-purity research, optical materials, MRI contrast
GA-2 ≥ 99.9% Crystalline powder Catalyst, ceramics, glass
GA-3 ≥ 99.5% Crystalline powder Industrial applications, general use

SECTION 6: FUNCTIONAL PROPERTIES AND MECHANISM OF ACTION

Property Explanation
Rare Earth Salt Derived from gadolinium element belonging to the lanthanide series. Consists of gadolinium ions (Gd³⁺) and acetate ions (C₂H₃O₂⁻).
MRI Contrast Agent Gadolinium compounds are used as contrast agents in magnetic resonance imaging (MRI). Gd³⁺ ions exhibit paramagnetic properties.
Catalyst Used as catalyst in automotive catalysts and organic synthesis.
Optical Materials Used in Gd³⁺-doped optical materials, phosphors and photonic materials.
Precursor Material Used as precursor for gadolinium oxide (Gd₂O₃) and other gadolinium compounds.
Hygroscopic Property Slightly hygroscopic, can absorb moisture from air. Should be stored in closed containers.

SECTION 7: MAIN APPLICATION AREAS

Industry / Application Function Typical Use
Medical Imaging MRI contrast agent Used as contrast agent in magnetic resonance imaging (MRI).
Catalyst Production Catalyst Used as catalyst in automotive catalysts and organic synthesis.
Optical Materials Optical dopant Used in Gd³⁺-doped optical materials, phosphors and photonic materials.
Ceramics and Glass Colorant and polishing Used in glass polishing and advanced ceramics.
Chemical Synthesis Precursor Precursor for gadolinium oxide and other gadolinium compounds.
Research Reagent Used as a reagent in rare earth chemistry research.

SECTION 8: MRI CONTRAST AGENT APPLICATIONS - DETAILED EXPLANATION

Parameter Explanation
Application Used as contrast agent in magnetic resonance imaging (MRI).
Operating Principle Gd³⁺ ions exhibit paramagnetic properties; Shortens T1 relaxation time, increasing image contrast.
Advantages High contrast; Good tolerance; Rapid elimination; Widespread use.
Application Areas Brain imaging; Cardiac imaging; Liver imaging; Oncological imaging.

SECTION 9: QUALITY SPECIFICATIONS

Parameter Specification (GA-1 - ≥99.99%) Test Method
Appearance White crystalline solid Visual
Purity (Gd(C₂H₃O₂)₃·4H₂O) ≥ 99.99% AAS / ICP / GDMS
Gadolinium Oxide (Gd₂O₃) ≥ 40.0% AAS / ICP
Iron (Fe) ≤ 0.001% AAS / ICP / GDMS
Calcium (Ca) ≤ 0.001% AAS / ICP / GDMS
Magnesium (Mg) ≤ 0.001% AAS / ICP / GDMS
Silicon (Si) ≤ 0.001% AAS / ICP / GDMS
Aluminum (Al) ≤ 0.001% AAS / ICP / GDMS
Other Rare Earths ≤ 0.01% ICP / GDMS
Chloride (Cl⁻) ≤ 0.01% Ion Chromatography
Sulfate (SO₄²⁻) ≤ 0.01% Ion Chromatography
Moisture ≤ 0.5% Karl Fischer
Form Crystalline powder Visual

SECTION 10: TOXICOLOGICAL PROFILE

Parameter Value
Acute Oral Toxicity Low toxicity
Acute Inhalation Toxicity Dust inhalation may cause irritation
Skin Irritation May be irritating
Eye Irritation May cause serious eye irritation
Chronic Toxicity Rare earth compounds may show health effects with prolonged exposure
Carcinogenicity Not classified as carcinogenic
Mutagenicity Not classified as mutagenic
Target Organs Respiratory system (dust irritation); Skin; Eyes
Special Toxicity Note Irritant; May cause irritation to skin, eyes and respiratory tract; Protect from moisture due to hygroscopic property

SECTION 11: GHS CLASSIFICATION AND LABELING

GHS Classification (in compliance with CLP and UN GHS):

Hazard Class Category H-Statement
Skin Irritation Category 2 H315
Serious Eye Damage/Irritation Category 1 H318
STOT - SE (Single Exposure) Category 3 H335 (optional)

Signal Word: DANGER

Hazard Pictograms: GHS05 (Corrosive), GHS07 (Irritant)

Hazard Statements (H-Codes):

Code Statement
H315 Causes skin irritation
H318 Causes serious eye damage
H335 May cause respiratory irritation

SECTION 12: PRECAUTIONARY STATEMENTS (P-CODES)

Code Statement
P261 Avoid breathing dust/fume/gas/mist/vapors/spray
P264 Wash hands thoroughly after handling
P271 Use only outdoors or in a well-ventilated area
P280 Wear protective gloves/protective clothing/eye protection/face protection
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses. Continue rinsing
P310 Immediately call a POISON CENTER/doctor
P312 Call a POISON CENTER/doctor if you feel unwell
P362+P364 Take off contaminated clothing and wash it before reuse
P403+P233 Store in a well-ventilated place. Keep container tightly closed
P501 Dispose of contents/container in accordance with local/regional/national/international regulations

SECTION 13: FIRST AID MEASURES

Exposure Route Action to Take
Inhalation Move to fresh air immediately. Keep at rest in a position comfortable for breathing. If symptoms persist, get medical attention.
Skin Contact Remove contaminated clothing immediately. Wash skin with plenty of soap and water. If skin irritation occurs, get medical advice/attention.
Eye Contact Rinse immediately with plenty of water for at least 15 minutes. Keep eyelids open. Remove contact lenses. Continue rinsing. Seek immediate medical attention.
Ingestion Rinse mouth with water. Do NOT induce vomiting. Drink plenty of water. Seek immediate medical attention.

SECTION 14: FIRE-FIGHTING MEASURES

Parameter Information
Fire Hazard Not flammable. May release toxic fumes at high temperatures.
Hazards During Fire May release gadolinium oxide and organic decomposition products at high temperatures
Suitable Extinguishing Media Dry chemical powder, CO₂, water spray, alcohol-resistant foam
Unsuitable Extinguishing Media Water jet
Special Protective Equipment Self-contained breathing apparatus (SCBA), full protective clothing
Special Precautions Prevent dust from entering sewers and waterways; Do not inhale fumes

SECTION 15: STORAGE AND SHELF LIFE

Parameter Information
Storage Conditions Cool, dry, well-ventilated area; Protect from moisture and light; In closed containers; Keep in original packaging
Container Requirements Airtight containers; Tightly closed due to hygroscopic property
Materials to Protect From Strong bases, reducing agents, oxidizing agents, moisture
Shelf Life 2-3 years (under proper storage conditions)
Stability Note Slightly hygroscopic; Absorbs moisture; Store in closed containers

SECTION 16: PACKAGING OPTIONS

Packaging Type Quantity Material
Plastic Drum 25-50 kg HDPE (airtight)
Plastic Bucket 5-25 kg HDPE (airtight)
Glass Bottle 100 g - 2 kg Glass (airtight)
Plastic Bag 1-10 kg PE (sealed)
Flexibag 100-500 kg PE lined

SECTION 17: TRANSPORT INFORMATION

Parameter Information
UN Number Not regulated (not dangerous)
Hazard Class Not applicable
Packing Group Not applicable
ADR/RID Not regulated
IMDG Code Not regulated
IATA (Air) Not regulated
Marine Pollutant No
Transport Temperature Ambient temperature; Protect from moisture

SECTION 18: OTHER NAMES AND SYNONYMS

Type Name
Turkish Names Gadolinyum Asetat, Gadolinyum Asetat Tetrahydrat, Gadolinyum Asetat Hidrat, Gadolinyum Asetat Susuz
English Names Gadolinium Acetate, Gadolinium Acetate Tetrahydrate, Gadolinium Acetate Hydrate, Gadolinium Acetate Anhydrous
German Names Gadoliniumacetat, Gadoliniumacetat Tetrahydrat, Gadoliniumacetat Hydrat
French Names Acétate de Gadolinium, Acétate de Gadolinium Tétrahydraté, Acétate de Gadolinium Hydraté
Spanish Names Acetato de Gadolinio, Acetato de Gadolinio Tetrahidratado, Acetato de Gadolinio Hidratado
Chemical Names Gadolinium(3+) acetate; Gadolinium triacetate
CAS Numbers 31298-16-5 (Anhydrous); 15280-53-2 (Tetrahydrate); 100587-93-7 (Hydrate Variant)
EC Number 240-204-9
Chemical Formula Gd(C₂H₃O₂)₃·4H₂O

SECTION 19: SUMMARY TABLE

Parameter Tetrahydrate Anhydrous
Product Gadolinium Acetate Tetrahydrate Gadolinium Acetate Anhydrous
CAS Number 15280-53-2 31298-16-5
Chemical Formula Gd(C₂H₃O₂)₃·4H₂O Gd(CH₃COO)₃
Molecular Weight ~352.37 g/mol ~370.53 g/mol
Appearance White crystalline solid White powder
Common Use Most common commercial form Special synthesis
Solubility Soluble in water Soluble in water

SECTION 20: CRITICAL WARNINGS AND BEST PRACTICES

CRITICAL WARNINGS:

  1. May cause serious eye damage. Eye protection is mandatory. Seek immediate medical attention upon contact.

  2. Irritant. May cause irritation to skin and respiratory tract. Use appropriate protective equipment.

  3. Slightly hygroscopic (absorbs moisture). Store in closed containers in dry environment.

  4. Decomposes upon heating and may release organic decomposition products.

  5. Rare earth compound requires special handling and purity considerations.

  6. MRI contrast agent applications require high purity (≥99.99%).

  7. Incompatibilities: Strong bases, reducing agents, oxidizing agents, moisture.

  8. Hygiene Requirement: Wash hands thoroughly after use. Remove contaminated clothing.

BEST PRACTICE RECOMMENDATIONS:

9. MRI Contrast Agent Production:
Use high-purity (≥99.99%) GA-1 grade for magnetic resonance imaging (MRI).

10. Catalyst Production:
Use as catalyst in automotive catalysts and organic synthesis.

11. Optical Materials:
Use in Gd³⁺-doped optical materials, phosphors and photonic materials.

12. Chemical Synthesis:
Use as precursor for gadolinium oxide and other gadolinium compounds.

13. Research:
Use as a reagent in rare earth chemistry studies.

14. Form Selection:
For common use, prefer tetrahydrate form (15280-53-2). For special synthesis, prefer anhydrous form (31298-16-5).

15. Use:
Use in well-ventilated areas; Avoid dust formation; Wear protective gloves, safety goggles and appropriate respiratory protection.

16. Personal Protective Equipment:
Use protective gloves (nitrile, neoprene), chemical safety goggles, full face shield, protective clothing.

17. Hygiene:
Do not eat, drink or smoke while using; Wash hands thoroughly after use; Do not take contaminated work clothes home.

18. Storage:
Store in cool, dry, well-ventilated area; Protect from moisture and light; Store in closed, airtight containers.

19. Spill Response:
Avoid dust formation; Vacuum or sweep; Place in closed containers; Do not allow to enter drains or waterways.

20. Disposal:
Dispose in accordance with local, regional and national regulations; Contact licensed waste disposal services for rare earth compounds.

GADOLINIUM ACETATE SELECTION GUIDE:

Application Recommended Form Explanation
MRI contrast agent Tetrahydrate (≥99.99%) Highest purity required
Catalyst Tetrahydrate (≥99.9%) High purity required
Optical materials Tetrahydrate (≥99.99%) Highest purity required
Chemical synthesis Both forms Depends on application
Research Tetrahydrate (≥99.99%) High purity required

RECOMMENDED STORAGE CONDITIONS:

Parameter Requirement
Storage Temperature Room temperature (15-25°C)
Humidity <60% relative humidity
Container Airtight containers
Location Cool, dry, well-ventilated area

LEGAL DISCLAIMER:

The information provided in this document is based on our current knowledge and experience and is provided in good faith; however, since all conditions of use are beyond our control, it does not constitute a binding specification or warranty. This Technical Data Sheet is for informational purposes only. Users are responsible for testing suitability for their own applications. For complete safety, storage, use, handling, disposal and regulatory compliance information, reference should be made to the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier.

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