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Lutetium Chloride Hexahydrate, Lutetium Trichloride Hexahydrate, 15230-79-2

Lutetium Chloride Hexahydrate, Lutetium Trichloride Hexahydrate, 15230-79-2

LUTETIUM CHLORIDE HEXAHYDRATE (LUCL₃·6H₂O)
LUTETIUM CHLORIDE HEXAHYDRATE / LUTETIUM TRICHLORIDE HEXAHYDRATE
1. PRODUCT IDENTIFICATION AND CHEMICAL IDENTITY

Parameter Information
Product Name Lutetium Chloride Hexahydrate
Chemical Name Lutetium(III) Chloride Hexahydrate, Lutetium Trichloride Hexahydrate
Other Names LuCl₃·6H₂O
CAS Number 15230-79-2
EC Number (EINECS) 236-526-1 (anhydrous form)
Chemical Formula LuCl₃·6H₂O
Molecular Weight 384.31 g/mol
Appearance White crystalline solid, hygroscopic
Odor Odorless
Physical State (20°C) Solid (crystalline)

2. CHEMICAL STRUCTURE
2.1. Molecular Structure
Lutetium chloride hexahydrate is the hydrated form of the chloride salt of the rare earth element lutetium. Lutetium ions (Lu³⁺) and chloride ions (Cl⁻) are present in a 1:3 ratio. Each lutetium chloride unit contains six molecules of water of hydration. Due to its hygroscopic nature, it is sensitive to degradation in humid environments. It exhibits high solubility in water.

Structural Features:

                    LUTETIUM CHLORIDE HEXAHYDRATE [LuCl₃·6H₂O]
                          |
                Lu³⁺ - Cl⁻ Ionic Bonds + 6H₂O
                          |
        +----------------+----------------+
        |                |                |
    White Crystalline  High Solubility   Highly
                       in Water          Hygroscopic

2.2. Structural Properties

Parameter Value
Crystal Structure Monoclinic
Chemical Formula LuCl₃·6H₂O
Molecular Weight 384.31 g/mol
Density ~2.6 g/cm³
Appearance White crystalline solid
Melting Point ~95 °C (hydrated form, decomposes with water loss)
pH (1M solution) Slightly acidic (~5.0-6.0)

3. PHYSICAL AND CHEMICAL PROPERTIES

Property Value Description
Appearance White crystalline solid -
Odor Odorless -
Chemical Formula LuCl₃·6H₂O -
Molecular Weight 384.31 g/mol -
Density ~2.6 g/cm³ -
Melting Point ~95 °C Hydrated form
Solubility in Water (25°C) High solubility -
Solubility in Alcohol Soluble -
Solubility in Acids Soluble -
pH (1M solution) Slightly acidic (~5.0-6.0) -
Stability Hygroscopic Must be stored in moisture-free conditions
Hygroscopicity High Absorbs moisture from air

4. PURITY GRADES

Parameter Technical Grade High Purity Grade Analytical Grade
Purity (LuCl₃·6H₂O) ≥ 99.0% ≥ 99.5% ≥ 99.9%
Lutetium (Lu) Content ≥ 45.0% ≥ 45.5% ≥ 45.8%
Other Rare Earths ≤ 1.0% ≤ 0.5% ≤ 0.1%
Iron (Fe) ≤ 100 ppm ≤ 50 ppm ≤ 20 ppm
Calcium (Ca) ≤ 100 ppm ≤ 50 ppm ≤ 20 ppm
Sodium (Na) ≤ 100 ppm ≤ 50 ppm ≤ 20 ppm
Lead (Pb) ≤ 50 ppm ≤ 20 ppm ≤ 10 ppm
Sulfate (SO₄²⁻) ≤ 0.2% ≤ 0.1% ≤ 0.05%
Nitrate (NO₃⁻) ≤ 0.2% ≤ 0.1% ≤ 0.05%
Chloride (Cl⁻) ≥ 27.5% ≥ 28.0% ≥ 28.3%
Loss on Drying Variable Variable Variable
Particle Size (D50) 10-50 µm 5-20 µm 1-10 µm

5. STABILITY AND REACTIVITY

Parameter Information
Chemical Stability Hygroscopic; stable under dry, closed conditions.
Conditions to Avoid High humidity, exposure to open atmosphere, prolonged air contact, high temperatures.
Incompatible Materials Strong oxidizing agents, strong acids, alkali metals.
Hazardous Decomposition Products At high temperatures: hydrogen chloride (HCl) and lutetium oxychloride (LuOCl).
Hazardous Polymerization Will not occur.
Hygroscopicity High; when exposed to air, it absorbs moisture and tends to deliquesce (become liquid).

5.1. Chemical Reactions

  • Thermal Decomposition (Hydrated Form):
    LuCl₃·6H₂O → LuCl₃ + 6H₂O (~100-150°C)
    LuCl₃ + H₂O → LuOCl + 2HCl (hydrolysis at high temperature)

  • Behavior in Aqueous Solution:
    LuCl₃(aq) → Lu³⁺(aq) + 3Cl⁻(aq)

  • Precipitation with Alkali:
    LuCl₃ + 3NaOH → Lu(OH)₃↓ + 3NaCl

6. APPLICATION AREAS
6.1. Research

Application Function Details
Lutetium Compound Research Biomedical and catalytic studies Properties of lutetium compounds
Coordination Chemistry Starting material Coordination complexes
Standard Preparation Reference material Calibration and analysis studies

6.2. Optical Materials

Application Function Details
Laser Crystals Additive Special laser systems
Phosphor Production Additive Special phosphor formulations
Optical Glasses Rare earth additive Special optical applications

6.3. Catalyst Applications

Application Function Details
Organic Synthesis Catalyst Catalytic activity Various organic transformations
Polymerization Catalyst Polymerization initiator Some polymerization reactions
Lewis Acid Acid catalyst Friedel-Crafts and other acid-catalyzed reactions

6.4. Nuclear Industry

Application Function Details
Radiopharmaceutical Research With lutetium isotopes Nuclear medicine research
Nuclear Material Research Special nuclear applications Research and development

6.5. Sectoral Suitability Table

Sector Suitability Explanation
Electronics Suitable Optical materials, semiconductors
Optical Materials Suitable Laser crystals, phosphors
Ceramics/Glass Suitable Specialty glasses, ceramics
Catalyst Suitable Organic synthesis, polymerization
Research Suitable Biomedical, catalytic, nuclear studies
Nuclear Suitable Radiopharmaceutical research
Water Treatment Not Suitable Not suitable
Food Not Suitable Not suitable
Cosmetics Not Suitable Not suitable

7. PRODUCTION PROCESS

Stage Process Description
1. Raw Material Preparation Lutetium oxide (Lu₂O₃) High purity lutetium oxide obtained
2. Acid Dissolution Dissolution in hydrochloric acid (HCl) Lu₂O₃ + 6HCl → 2LuCl₃ + 3H₂O
3. Filtration Removal of impurities Insoluble impurities are filtered out
4. Concentration Evaporation Solution is concentrated
5. Crystallization Hydrated form LuCl₃·6H₂O crystallized
6. Drying Controlled conditions Crystals dried under appropriate conditions
7. Packaging Moisture-proof packaging Packaged in moisture-proof containers due to hygroscopic nature

7.1. Alternative Production Method

Method Description
Solvent Extraction Purification after solvent extraction from rare earth ores

7.2. Major Producing Countries

Country Description
China Major producer
USA Rare earth production (Sigma-Aldrich, Alfa Aesar)
Germany High purity production
Japan High purity production

8. ALTERNATIVE / SUBSTITUTE PRODUCTS

Alternative Description When to Use
Lutetium Oxide (Lu₂O₃) Lutetium source When oxide form is required
Lutetium Nitrate (Lu(NO₃)₃) Lutetium source When different anion is required
Lutetium Acetate Organic synthesis When organic solvent compatibility is required
Yttrium Chloride (YCl₃) Similar chemical properties When Y is required
Gadolinium Chloride (GdCl₃) Similar chemical properties When Gd is required

9. SAFETY AND TOXICOLOGY

Parameter Value
Acute Oral Toxicity (LD50, Rat) > 2,000 mg/kg (low toxicity)
Dermal Toxicity Low
Skin Irritation Mild to moderate irritant
Eye Irritation Serious irritant
Inhalation Dust inhalation may cause respiratory tract irritation.
Carcinogenicity Not classified as carcinogenic.
Mutagenicity Not mutagenic.
Chronic Effects Rare earth compounds have low bioavailability; however, high doses may cause liver effects.
Environmental Hazards Moderate aquatic toxicity; caution required due to chloride ion content.

9.1. GHS Classification

Hazard Class Category H-Statement
Skin Irritation Category 2 H315: Causes skin irritation.
Eye Irritation Category 2A H319: Causes serious eye irritation.
Specific Target Organ Toxicity Category 3 H335: May cause respiratory irritation.

Signal Word: WARNING

Hazard Pictograms: GHS07 (Exclamation Mark)

10. PRECAUTIONARY STATEMENTS (P-CODES)

Code Statement
P261 Avoid breathing dust.
P264 Wash thoroughly after handling.
P271 Use only in well-ventilated areas.
P280 Wear protective gloves/eye protection/face protection.
P302+P352 IF ON SKIN: Wash with plenty of soap and water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do.
P337+P313 If eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container in accordance with local regulations.

11. FIRST AID MEASURES

Exposure Route Action to Take
Inhalation Remove to fresh air. If symptoms persist, seek medical attention.
Skin Contact Wash with plenty of soap and water. Remove contaminated clothing. If irritation persists, seek medical attention.
Eye Contact Rinse thoroughly with plenty of water for at least 15 minutes. Remove contact lenses. If irritation persists, seek medical attention.
Ingestion Rinse mouth. Drink plenty of water. If large amount is swallowed, seek medical attention.

12. STORAGE AND SHELF LIFE

Parameter Condition
Storage Conditions Store in a cool, dry, and well-ventilated area. Ensure a moisture-free environment.
Container Requirements Moisture-proof, airtight, tightly closed containers. Glass bottle or PTFE-lined containers.
Temperature Room temperature (15-25°C).
Shelf Life 12-18 months under appropriate conditions (due to hygroscopic nature).
Stability Note Highly hygroscopic; rapidly degrades in humid environments. If left open, Lu(OH)₃ and Lu₂(CO₃)₃ may form.

13. PACKAGING OPTIONS

Packaging Type Quantity Material
Laboratory Packaging 1 g, 5 g, 10 g, 25 g Glass bottle, sealed cap, inert atmosphere
Laboratory Packaging 50 g, 100 g HDPE bottle, inert atmosphere
Industrial Packaging 25 kg PE-lined bag, moisture-proof
Drum 25 kg, 50 kg HDPE drum, moisture-proof

14. TRANSPORT INFORMATION

Parameter Information
UN Number Not classified (specific regulations apply for rare earth compounds)
Hazard Class -
Packing Group -
ADR/RID Not regulated
IMDG Not regulated
IATA Not regulated
HS Code 2846.90.00.00.19 (Other rare earth compounds)

15. REGULATORY STATUS

Region / Authority Status
European Union (REACH) Registered
Turkey (KKDIK) Compliance required
TSCA (USA) Registered
CLP/GHS Compliant
FDA/EFSA Not approved as a food additive
ISO 9001:2015 Production compliance

16. OTHER NAMES AND SYNONYMS

Name Description
Lutetium Trichloride Hexahydrate Chemical name
Lutetium(III) Chloride Hexahydrate Chemical name
LuCl₃·6H₂O Chemical abbreviation
Lutetium Chloride Hexahydrate English name
Lutetium Trichloride Hexahydrate English name

17. QUICK REFERENCE TABLE

Property Value
CAS Number 15230-79-2
EC Number 236-526-1
Chemical Formula LuCl₃·6H₂O
Molecular Weight 384.31 g/mol
Appearance White crystalline solid
Density ~2.6 g/cm³
Melting Point ~95 °C (hydrated form)
Solubility in Water High solubility
HS Code 2846.90.00.00.19
GHS Signal Word WARNING

18. CRITICAL WARNINGS AND BEST PRACTICES

CRITICAL WARNINGS:

  • Highly Hygroscopic Nature: Lutetium chloride hexahydrate has a very high moisture absorption capacity. When exposed to air, it rapidly absorbs moisture, begins to dissolve, and loses its quality. Extreme care must be taken to avoid moisture during storage and handling.

  • Thermal Decomposition: Above ~100-150°C, water loss begins; at higher temperatures, toxic hydrogen chloride (HCl) gas is released. Ventilation is essential.

  • Incompatibility: Contact with strong oxidizing agents creates a fire and explosion risk.

  • Eye and Skin Irritation: Due to its acidic nature, it causes irritation to skin and eyes. Protective equipment is mandatory during use.

  • High Value: Lutetium is a critical and valuable rare earth element for optical, laser, and nuclear applications; losses should be minimized and recycling options explored.

BEST PRACTICE RECOMMENDATIONS:

  • Storage:

    • Store in a cool, dry, and well-ventilated area.

    • Use moisture-proof, airtight containers.

    • Keep away from oxidizing agents.

    • Store at room temperature (15-25°C).

  • Handling:

    • Immediately close containers tightly when not in use.

    • Ensure a dry working environment during use (humidity control).

    • Use a dust mask (N95 or better), protective goggles, and chemically resistant gloves.

    • Avoid dust formation and inhalation.

    • Wash hands thoroughly after handling.

    • When preparing solutions, add slowly due to acidic character.

  • Waste Management:

    • Dispose of in accordance with local regulations as heavy metal waste.

    • Do not discharge into water sources or sewers.

    • For large quantities, rare earth recovery should be considered.

LEGAL DISCLAIMER
This Technical Data Sheet (TDS) is for informational purposes only and has been prepared based on available technical data. The user is solely responsible for determining the suitability of the product for their specific applications and for complying with all local, national, and international regulations. For complete safety, storage, handling, transport, disposal, and regulatory compliance information, the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier must be consulted. This document does not substitute professional advice. Lutetium chloride hexahydrate requires careful handling and storage due to its highly hygroscopic nature and value; it is an important raw material for research, optical, catalyst, and nuclear applications.

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