Creatine Pyruvate, Pyruvate Creatine Complex, 55965-97-4

Creatine Pyruvate, Pyruvate Creatine Complex, 55965-97-4

(CAS No. 55965-97-4)

A) Physical and Chemical Properties

• Chemical Name: Creatine Pyruvate (Creatine + Pyruvic Acid salt)

• Molecular Formula: C₇H₁₃N₃O₅

• Molecular Weight: 219.20 g/mol

• Appearance: White crystalline powder

• Melting Point: >200 °C (decomposes)

• Boiling Point: ~271.6 °C (760 mmHg)

• Density: ~1.4 g/cm³ (estimated)

• Solubility: Soluble in water

• Storage: 2–8 °C, dry and sealed

B) Detailed Applications

• Sports Nutrition: Enhances muscle strength, endurance, and recovery

• Energy Metabolism: Supports ATP production via creatine and aerobic metabolism via pyruvate

• Antioxidant Role: May reduce oxidative stress from intense exercise

• Weight Management: Studied for fat metabolism and body composition benefits

• Neuroprotective Research: Explored for synergistic effects in brain energy metabolism

C) Synonyms

• Pyruvate-Creatine Complex

• 2-Oxo-propanoic acid Pyruvate-creatine mixt

• N-(Aminoiminomethyl)-N-methylglycine mixt. with 2-oxopropanoic acid

• Creatine Pyruvate Fusion

• CAS: 55965-97-4

D) Production Method

1. Reaction of Creatine with Pyruvic Acid:

Creatine+Pyruvic Acid→Creatine Pyruvate\text{Creatine} + \text{Pyruvic Acid} \rightarrow \text{Creatine Pyruvate}

2. Crystallization and drying

3. Typically formulated as 60% creatine + 40% pyruvate by weight

E) Alternative Products

• Creatine Monohydrate – Most studied and cost-effective

• Creatine Citrate – Better solubility, higher cost

• Calcium Pyruvate – Used in fat metabolism and weight loss

• Creatine HCl – High solubility, limited data

• Beta-Alanine, HMB – Non-creatine performance enhancers

F) Common Names

• Creatine-Pyruvate Blend

• Energy Complex

• Muscle Power Salt

• Endurance Creatine

G) Reactions

• In Acidic Stomach: Dissociates into creatine and pyruvic acid

• Creatine: Converts to phosphocreatine → ATP regeneration

• Pyruvate: Enters TCA cycle → aerobic energy production

• Antioxidant Action: May scavenge free radicals

• Plasma Creatine Uptake: Higher than monohydrate in some studies