Magnesium Pyruvate, Magnesiumpyruvate, 81686-75-1

Magnesium Pyruvate, Magnesiumpyruvate, 81686-75-1

(CAS No. 81686-75-1)

A) Physical and Chemical Properties

• Chemical Name: Magnesium bis(2-oxopropanoate)

• Molecular Formula: C₆H₆MgO₆

• Molecular Weight: 198.41 g/mol

• Appearance: White to cream-colored crystalline powder

• Melting Point: >200 °C (decomposes)

• Boiling Point: ~165 °C at 760 mmHg

• Solubility: Soluble in water, slightly soluble in ethanol

• pH (1% solution): ~6.5–7.5

• Storage: Store in a dry, cool, inert atmosphere (e.g. nitrogen)

B) Detailed Applications

• Pharmaceuticals & Neurology: NMDA receptor modulation, migraine prevention, neuroprotection

• Sports Nutrition: Enhances lactate clearance, reduces cramps, supports mitochondrial ATP production

• Food Technology: Natural antioxidant (TBHQ alternative), meat color stabilizer, bakery shelf-life extender

• Acid Neutralization: Buffers gastric acid (pH 3.8–5.2) with minimal electrolyte disruption

• Industrial: Biodegradable polymer synthesis, NOx reduction, battery electrolyte enhancement

C) Synonyms

• Magnesium pyruvate

• Pyruvic acid magnesium salt

• Magnesium bis(2-oxopropanoate)

• Propanoic acid, 2-oxo-, magnesium salt (2:1)

• MAGNESIUM (2+) DIPYRUVATE

• Magnesiumpyruvate

D) Production Method

1. Neutralization of Pyruvic Acid with Magnesium Oxide:

2CH3COCOOH+MgO→(CH3COCOO)2Mg+H2O2CH₃COCOOH + MgO → (CH₃COCOO)₂Mg + H₂O

2. Followed by crystallization, filtration, and vacuum drying

3. Pyruvic acid may be sourced via microbial fermentation

E) Alternative Products

• Sodium Pyruvate – Common in cell culture

• Calcium Pyruvate – Used in sports supplements

• Magnesium Citrate / Glycinate – Alternative magnesium sources

• Magnesium Malate – Energy metabolism support

• Magnesium Oxide – Acid neutralizer with lower bioavailability

F) Common Names

• Energy Magnesium

• Fat-Burning Magnesium

• Magnesium Pyruvate Supplement

• Muscle Support Magnesium

G) Reactions

• Converts to pyruvic acid in acidic media

• Reduces to lactic acid under anaerobic conditions

• Decarboxylates to acetyl-CoA in mitochondria

• Scavenges ROS as an antioxidant

• Buffers pH in gastric and metabolic systems