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Dodecyl Alcohol, Lauryl Alcohol, Dodecanol, 112-53-8

Dodecyl Alcohol, Lauryl Alcohol, Dodecanol, 112-53-8

Dodecyl Alcohol (Lauryl Alcohol, CAS: 112-53-8) 

1. Product Identity

Property Details
Product Name Dodecyl Alcohol / Lauryl Alcohol
CAS Number 112-53-8
Molecular Formula C₁₂H₂₆O
Molecular Weight 186.34 g/mol
Chemical Name n-Dodecanol, 1-Dodecanol
Common Names Lauryl alcohol, n-Dodecyl alcohol, Alcohol C-12, Dodecan-1-ol
Trade Names Epal 12, Adol 12, Nacol 12-96

2. Physical and Chemical Properties

Property Value
Appearance Colorless to pale yellow, oily liquid (solidifies below 24°C)
Odor Profile Mild, fatty, waxy odor
Density (20°C) 0.8309 g/mL
Melting Point 24 °C
Boiling Point 259 °C
Flash Point 127 °C
Refractive Index (nᵈ) 1.442
Solubility Very slightly soluble in water; soluble in ethanol and diethyl ether
Volatility Low vapor pressure; limited odor emission in processes and formulations
Stability Stable under normal conditions; may react with strong oxidizing agents

3. Production and Quality

Production Processes

Process Type Description
Natural Source-Based Hydrogenation of lauric acid derived from coconut oil and palm kernel oil
Synthetic Process Ziegler process (polymerization of ethylene to long-chain alkyls, followed by oxidation and reduction steps)

Typical Quality Parameters

Parameter Specification
Purity (GC) ≥ 98–99%
Acid Value Low (minimal free acid)
Water Content (Karl Fischer) ≤ 0.1–0.2%
Color (APHA/Hazen) Low color number, preferred for cosmetic grades
Odor Neutral to mild; suitable for perfumery and personal care

Supply Forms

  • Bulk liquid (IBC, drums)

  • Near-solid packaging (requires heating jackets during shipment in cold weather)

Certifications

  • Cosmetic grades: IFRA/Allergen compliance declarations

  • Industrial grades: COA, TDS, SDS

  • Limited food use: Compliance declarations as applicable

4. Synonyms and Other Names

Common Names

  • Lauryl alcohol

  • n-Dodecanol

  • n-Dodecyl alcohol

  • Alcohol C-12

  • Dodecan-1-ol

Trade Names / Brands

  • Epal 12

  • Adol 12

  • Nacol 12-96

5. Applications and Functions

5.1. Detergents and Surfactant Systems

Function Description
Precursor As a long-chain fatty alcohol, it is the precursor for sulfate/sulfonate derivatives such as SLS/SLES
Performance Positive effect on grease removal, foam formation, and foam stability
Formulation Role Co-surfactant, foam modulator, viscosity regulator

5.2. Cosmetics and Personal Care

Function Description
Emulsifier/Co-emulsifier Balances water-oil phases, improves texture
Moisturizer and Emollient Helps reduce transepidermal water loss
Rheology Modifier Thickens creams and lotions; adjusts hardness in balms and sticks
Fragrance Matrix Mild waxy profile serves as a fragrance carrier and odor blender

5.3. Pharmaceutical (Topical Focus)

Function Description
Excipient Emollient/carrier in ointments, creams, and lotions
Emulsion Agent Supports distribution of active ingredients and extends shelf life
Taste/Odor Masking Limited; oral use requires regulatory compliance

5.4. Lubricants and Industrial Applications

Function Description
Friction Reducer Added to base oils to provide a film-forming fatty phase
Corrosion Inhibitor Systems Passive protection additive in coatings and metalworking fluids
Polymer Processes Wetting agent/carrier in emulsion polymerization; stability support

5.5. Perfume and Fragrance Industry

Function Description
Precursor Compound Raw material for dodecanal synthesis (fatty alcohol to aldehyde conversion)
Fragrance Carrier Improves solubility and diffusion of essential oils

5.6. Food Industry (Limited)

Function Description
Carrier/Emulsion Agent Used in some aroma systems; no E-number, local regulatory compliance required

6. Industry Suitability Tables

Lauryl Alcohol (Dodecanol) – Industry Suitability Overview

Industry Application Area Suitability Notes
Cosmetics Moisturizer, emulsion stabilizer, viscosity enhancer, hair shine High Considered safe, low irritation risk at low concentrations
Detergents Surfactant, foaming, cleaning power, SLS derivatives High Common in household cleaning products, provides foam control
Pharmaceutical Excipient, carrier solvent, formulation stabilizer Medium Controlled use required, subject to pharmaceutical regulations
Food Flavor and taste modifier, limited additive Limited Permitted as food additive but limited scope; no E-number
Polymer/Plastic Monomer production, industrial chemical applications High Used in polymer synthesis, critical in industrial-scale production
Agriculture Emulsion agent, adjuvant in pesticide formulations Medium Environmental effects must be considered; biodegradability is an advantage

Lauryl Alcohol (Dodecanol) – Cosmetics Industry Suitability Table

Application Area Function Suitability Notes
Moisturizer Prevents moisture loss by forming a barrier on skin High Common in dry skin products
Emulsion Stabilizer Balances water and oil phases, ensures homogeneous texture in creams High Critical role in creams, lotions, and makeup bases
Viscosity Enhancer Provides consistency, controls flow High Preferred in lotion, cream, and gel formulations
Hair Care Products Provides shine and softness, supports foaming effect High Common in shampoo and conditioner formulations
Fragrance/Fragrance Carrier Contributes to formulation with mild floral scent Medium Generally auxiliary component, not primary fragrance ingredient
Skin Safety Safe at low concentrations, may cause irritation at high doses Controlled Must be used at concentrations compliant with cosmetic regulations
Sustainability Biodegradable, environmentally friendly High Derived from natural sources, aligns with sustainable cosmetic trends

Lauryl Alcohol (Dodecanol) – Detergent Industry Suitability Table

Application Area Function Suitability Notes
Surfactant Dissolves dirt and grease, provides cleaning power High Critical role in household cleaning products
Foaming Effect Creates foam in shampoos, soaps, and liquid detergents High Enhances perception of cleanliness for consumers
Sodium Lauryl Sulfate (SLS) Most commonly used surfactant derived from lauryl alcohol High Standard ingredient in shampoos, dish detergents, and soaps
Foam Control Adjusts foam density, optimizes product performance Medium Used for foam balancing in industrial cleaning products
Grease Removal Power Dissolves oily dirt, enhances cleaning efficacy High Prominent in kitchen and industrial cleaning products
Environmental Compliance Biodegradable, environmentally friendly High Preferred in sustainable detergent formulations
Skin Safety Safe at low concentrations, may cause irritation at high doses Controlled Dermatological testing recommended for household cleaning products

Lauryl Alcohol (Dodecanol) – Pharmaceutical Industry Suitability Table

Application Area Function Suitability Notes
Excipient Carrier in tablet and capsule formulations, solubility enhancer High Increases stability in drug formulations
Solvent/Carrier Enhances solubility of active ingredients, ensures homogeneous distribution Medium Controlled use required, subject to pharmaceutical regulations
Emulsion Agent Balances water/oil phases in pharmaceuticals, ensures homogeneous structure High Preferred in oral and topical formulations
Topical Products Moisturizer and thickener in ointment and cream formulations High Strengthens skin barrier, functions as drug carrier
Flavor/Fragrance Modifier Aids in masking taste and odor in pharmaceuticals Limited Generally supporting role, not primary component
Safety Safe at low concentrations, may cause irritation at high doses Controlled Must be used at concentrations compliant with GMP and pharmaceutical regulations
Sustainability Biodegradable, environmentally friendly High Aligns with green pharmaceutical production trends

Lauryl Alcohol (Dodecanol) – Food Industry Suitability Table

Application Area Function Suitability Notes
Flavor Modifier Aids in masking taste and odor Limited Generally supporting role, not primary flavor component
Taste Masking Reduces undesirable tastes, provides balance in formulation Medium Limited use as food additive
Solvent/Carrier Enhances solubility of flavors and essential oils Medium Controlled use required, subject to food regulations
Emulsion Agent Balances oil-water phases, ensures homogeneous structure High Preferred in some beverage and flavor formulations
Food Additive Auxiliary agent in specific formulations Limited No E-number, limited permission depending on regulations
Sustainability Biodegradable, environmentally friendly High Derived from natural sources, aligns with green food trends
Safety Safe at low concentrations, may cause irritation at high doses Controlled Must be used at concentrations compliant with food regulations

Lauryl Alcohol (Dodecanol) – Polymer/Plastic Industry Suitability Table

Application Area Function Suitability Notes
Monomer Production Used as starting component in polymer synthesis High Critical role in polyethylene and polypropylene derivatives
Plastic Additive Enhances flexibility and durability High Provides performance optimization in plastic formulations
Emulsion Agent Balances water/oil phases in polymerization processes Medium Controlled use required, depends on process conditions
Solvent/Carrier Enhances solubility of some components in polymer production Medium Preferred in industrial-scale production
Stabilizer Increases thermal and chemical stability of polymers High Advantageous especially in high-temperature processes
Sustainability Biodegradable, environmentally friendly High Aligns with green plastic and eco-friendly polymer production trends

Lauryl Alcohol (Dodecanol) – Agriculture Industry Suitability Table

Application Area Function Suitability Notes
Emulsion Agent Balances water/oil phases in pesticide and herbicide formulations High Provides homogeneous mixing, increases product efficacy
Wetting/Spreading Agent Facilitates droplet spreading on plant surfaces High Ensures better coverage on leaf surfaces
Carrier Solvent Enhances solubility of active ingredients, ensures homogeneous distribution Medium Controlled use required, subject to agrochemical regulations
Stabilizer Increases shelf life and efficacy of formulations High Critical role especially in liquid pesticides
Environmental Compliance Biodegradable, environmentally friendly High Advantageous for sustainable agricultural practices
Safety Safe at low concentrations, may affect plants and soil at high doses Controlled Must be used at concentrations compliant with agricultural regulations

7. Safety, Environment, and Storage

Safety

Parameter Details
Exposure May cause eye/skin irritation at high concentrations
First Aid Eye contact: Rinse with plenty of water; Skin contact: Wash with water and mild soap
Fire and Explosion Flash point 127 °C; classified as flammable liquid; use foam/dry chemical extinguishers

Environmental Impact

Parameter Details
Biodegradability Biodegradable due to natural origin and structure; generally not classified as hazardous to aquatic life
Spill Control Contain with soil/sorbent; avoid direct discharge into sewers

Storage and Handling

Parameter Details
Conditions Store in cool, dry, well-ventilated area in tightly closed containers
Compatibility Keep away from strong oxidizing agents; compatible with stainless steel/aluminum; risk of swelling in some elastomers
Thermal Management Viscosity increases/solidifies below 24°C; heating-jacketed IBC/drums ensure pumpability
Packaging 180–200 L drums, 1000 L IBC, bulk; minimize moisture and light exposure

8. Summary

Dodecyl Alcohol (Lauryl Alcohol, CAS: 112-53-8) is a long-chain fatty alcohol with the molecular formula C₁₂H₂₆O. It is a colorless to pale yellow oily liquid with a mild, waxy odor. It melts at 24°C, boils at 259°C, and is slightly soluble in water but soluble in ethanol and ether.

Key Advantages:

  • Biodegradable and environmentally friendly

  • Stable under normal conditions

  • Improves texture and performance in formulations

  • Versatile across multiple industries

Main Application Areas:

  • Cosmetics and Personal Care: Emollient, emulsifier, viscosity enhancer, hair shine agent

  • Detergents: Surfactant, foam booster, SLS precursor

  • Pharmaceuticals: Topical excipient, emulsion stabilizer

  • Industrial: Lubricant, corrosion inhibitor, polymer processing

  • Fragrance: Precursor for dodecanal synthesis, fragrance carrier

Production: Derived from natural sources (coconut oil, palm kernel oil) via hydrogenation of lauric acid, or synthetically via the Ziegler process.

Quality: Available in ≥99% purity with low color and water content; certified with IFRA, SDS, COA as required.

Safety: May be irritating at high concentrations; requires appropriate PPE, controlled storage, and fire safety measures.

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